1

Upstream Manufacturing Jobs (NOW HIRING)

The ideal candidate has deep handson experience with optical glass and crystalline materials, strong knowledge of upstream manufacturing processes, and a proven ability to build and manage a ...

Upstream Process Engineer II Location: Redmond, WA Reports to: Senior Manager, Upstream Process ... Partner with Manufacturing to develop high-quality batch records, robust processes and innovative ...

Leverage deep expertise in upstream manufacturing processes (including mammalian cell culture and gene therapy platforms) to troubleshoot and resolve complex manufacturing issues across internal ...

Upstream Process Engineer II Location: Redmond, WA Reports to: Senior Manager, Upstream Process ... Partner with Manufacturing to develop high-quality batch records, robust processes and innovative ...

PR · On-site

Proven experience as a Validation Engineer in a manufacturing environment. * Strong knowledge of upstream equipment and processes, including but not limited to: fermenters, bioreactors, centrifuges ...

Proven experience as a Validation Engineer in a manufacturing environment. * Strong knowledge of upstream equipment and processes, including but not limited to: fermenters, bioreactors, centrifuges ...

Proven experience as a Validation Engineer in a manufacturing environment. * Strong knowledge of upstream equipment and processes, including but not limited to: fermenters, bioreactors, centrifuges ...

next page

Showing results 1-20

Upstream Manufacturing information

See salary details

$13

$24

$34

How much do upstream manufacturing jobs pay per hour?

As of Jun 5, 2026, the average hourly pay for upstream manufacturing in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What is upstream manufacturing?

Upstream manufacturing refers to the initial stages of the production process in industries like biotechnology and pharmaceuticals, where raw materials such as cells, bacteria, or yeast are cultivated to produce a desired product. This stage typically includes activities like cell culture, fermentation, and media preparation. The goal is to optimize the growth and productivity of the biological system to ensure efficient production before moving to downstream processing, which involves purification and formulation of the final product.

What are some common challenges faced in upstream manufacturing, and how are they typically addressed by teams?

In upstream manufacturing, one of the main challenges is maintaining consistent cell culture conditions to optimize yield and product quality. Teams often face issues such as contamination, variability in raw materials, and equipment malfunctions. To address these challenges, upstream teams implement rigorous standard operating procedures (SOPs), utilize real-time monitoring systems, and collaborate closely with quality assurance and process engineering teams. Regular team meetings and cross-functional communication are key to quickly identifying and solving problems, ensuring smooth production runs.

What are the key skills and qualifications needed to thrive in Upstream Manufacturing, and why are they important?

To thrive in Upstream Manufacturing, you need a solid understanding of bioprocessing, cell culture techniques, and process engineering, often supported by a degree in biotechnology, chemical engineering, or a related field. Familiarity with bioreactors, process control systems, and cGMP regulations is typically required, along with certifications like Six Sigma or Lean Manufacturing being advantageous. Strong analytical thinking, attention to detail, and effective teamwork are essential soft skills for excelling in this field. These capabilities ensure efficient production, product quality, and compliance with industry standards in a highly regulated environment.

What is the difference between Upstream Manufacturing vs Downstream Manufacturing?

AspectUpstream ManufacturingDownstream Manufacturing
FocusRaw material extraction and initial processingFinal product assembly and packaging
Work EnvironmentFactories, extraction sitesAssembly lines, packaging facilities
CredentialsTechnical certifications, safety trainingQuality control, packaging certifications
Industry UsageOil & gas, chemicals, miningPharmaceuticals, food production, consumer goods

Upstream Manufacturing involves the extraction and initial processing of raw materials, while Downstream Manufacturing focuses on transforming these materials into finished products. Both roles are essential in the supply chain but differ in their processes, environments, and required skills.

More about Upstream Manufacturing jobs
What are the most commonly searched types of Upstream Manufacturing jobs? The most popular types of Upstream Manufacturing jobs are:
What states have the most Upstream Manufacturing jobs? States with the most job openings for Upstream Manufacturing jobs include:
Infographic showing various Upstream Manufacturing job openings in the United States as of May 2026, with employment types broken down into 50% Full Time, 17% Part Time, and 33% Nights. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $51,890 per year, or $24.9 per hour.
Additive Manufacturing Technician

Additive Manufacturing Technician

Lockheed Martin

Grand Prairie, TX • On-site

$61K - $107K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 10 days ago


Lockheed Martin rating

8.2

Company rating: 8.2 out of 10

Based on 378 frontline employees who took The Breakroom Quiz

30th of 59 rated aerospace companies


Job description

Job Description
You will be the Additive Manufacturing Technician for the Advanced Manufacturing Technologies team. Our team is responsible for operating and optimizing high-performance additive-manufacturing processes.
What You Will Be Doing
As the Additive Manufacturing Technician you will be responsible for running, maintaining, and improving critical furnace and machine operations that enable large-scale metal-additive production.
Your responsibilities will include, but are not limited to:
  • Run and maintain the solar vacuum furnace, including stress-relief and aging profiles.
  • Run and maintain the AIP HIP furnace for multiple material sets.
  • Build and resurface large-scale additive build plates, including EDM, surface grinding, and full inspection.
  • Operate and service two large-scale additive machines across two material families.
  • Provide job, consumable, and cost updates to customers and leadership while partnering with downstream and upstream manufacturing functions.

Why Join Us
The ideal candidate is a hands-on problem-solver who thrives in fast-paced, high-impact environments. You will work directly with cross-functional manufacturing teams, see your work translate into tangible production outcomes, and grow within a culture that rewards technical mastery.
We are committed to supporting your work-life balance and overall well-being, offering flexible scheduling options. Learn more about Lockheed Martin's comprehensive benefits package here.
Further Information About This Opportunity
This position is in Dallas. Discover more about our Dallas, Texas location.
MUST BE A U.S. CITIZEN - This position is located at a facility that requires special access.
Basic Qualifications
• Ability to obtain a Secret level clearance
• Experience in heat treatment, either vacuum furnaces or HIP furnaces, additive experience a plus.
• Strong problem-solving and independent thinking skills
• Ability to learn quickly on HMIs and manufacturing process documentation.
• Comfortable with flexibility in work scope and requirements and good attitude.
Desired skills
• Certifications in furnaces through Solar or AIP
• Experience with heat treatment programs and outcomes
• Experience with Aluminum and/or Inconel additive manufacturing or heat treatment
• CNC programming and EDM experience
• Bachelor's degree in Mechanical Engineering or similar engineering degree, or equivalent experience
EEO
Lockheed Martin is an equal opportunity employer. Qualified candidates will be considered without regard to legally protected characteristics.
The application window will close in 90 days; applicants are encouraged to apply within 5 - 30 days of the requisition posting date in order to receive optimal consideration.
*
At Lockheed Martin, we use our passion for purposeful innovation to help keep people safe and solve the world's most complex challenges. Our people are some of the greatest minds in the industry and truly make Lockheed Martin a great place to work.
With our employees as our priority, we provide diverse career opportunities designed to propel, develop, and boost agility. Our flexible schedules, competitive pay, and comprehensive benefits enable our employees to live a healthy, fulfilling life at and outside of work. We place an emphasis on empowering our employees by fostering an inclusive environment built upon integrity and corporate responsibility.
If this sounds like a culture you connect with, you're invited to apply for this role. Or, if you are unsure whether your experience aligns with the requirements of this position, we encourage you to search on Lockheed Martin Jobs, and apply for roles that align with your qualifications.
Other Important Information
By applying to this job, you are expressing interest in this position and could be considered for other career opportunities where similar skills and requirements have been identified as a match. Should this match be identified you may be contacted for this and future openings.
Work Schedule Information
Lockheed Martin supports a variety of alternate work schedules that provide additional flexibility to our employees. Schedules range from standard 40 hours over a five day work week while others may be condensed. These condensed schedules provide employees with additional time away from the office and are in addition to our Paid Time off benefits.
National Pay Statement
Pay Rate: The annual base salary range for this position in California, Massachusetts, and New York (excluding most major metropolitan areas), Colorado, Hawaii, Illinois, Maryland, Minnesota, New Jersey, Vermont, Washington or Washington DC is $61,200 - $107,985. For states not referenced above, the salary range for this position will reflect the candidate's final work location. Please note that the salary information is a general guideline only. Lockheed Martin considers factors such as (but not limited to) scope and responsibilities of the position, candidate's work experience, education/ training, key skills as well as market and business considerations when extending an offer.
Benefits offered: Medical, Dental, Vision, Life Insurance, Short-Term Disability, Long-Term Disability, 401(k) match, Flexible Spending Accounts, EAP, Education Assistance, Parental Leave, Paid time off, and Holidays.
(Washington state applicants only) Non-represented full-time employees: accrue at least 10 hours per month of Paid Time Off (PTO) to be used for incidental absences and other reasons; receive at least 90 hours for holidays. Represented full time employees accrue 6.67 hours of Vacation per month; accrue up to 52 hours of sick leave annually; receive at least 96 hours for holidays. PTO, Vacation, sick leave, and holiday hours are prorated based on start date during the calendar year.
Premium Pay Statement
Pay Rate: The annual base salary range for this position in most major metropolitan areas in California, Massachusetts, and New York is $70,400 - $117,415. For states not referenced above, the salary range for this position will reflect the candidate's final work location. Please note that the salary information is a general guideline only. Lockheed Martin considers factors such as (but not limited to) scope and responsibilities of the position, candidate's work experience, education/ training, key skills as well as market and business considerations when extending an offer.
Benefits offered: Medical, Dental, Vision, Life Insurance, Short-Term Disability, Long-Term Disability, 401(k) match, Flexible Spending Accounts, EAP, Education Assistance, Parental Leave, Paid time off, and Holidays.

What Lockheed Martin employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Lockheed Martin logo

About Lockheed Martin

Sourced by ZipRecruiter

As a global security and aerospace company, the majority of Lockheed Martin's business is with the U.S. Department of Defense and U.S. federal government agencies.The remaining portion of Lockheed Martin's business is comprised of international government and commercial sales of products, services and platforms.

Industry

Manufacturing

Company size

10,000+ Employees

Headquarters location

Bethesda, MD, US

Year founded

1912