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Upstream Manufacturing Jobs (NOW HIRING)

Raya Workforce

Process Engineer

Lincoln, NE · On-site

Drive improvements across upstream manufacturing and downstream packaging * Support line trials, startup activities, and project engineering (FAT/SAT) What we're looking for: * 7-10+ years in FDA ...

Arcadis

Process Engineer

Holly Springs, NC · On-site

Arcadis is seeking a Process Engineer - Upstream Manufacturing to support large-scale biologics production at its Holly Springs facility. This role will focus on upstream operations including cell ...

Kenvue

Manufacturing Operator Upstream

Las Piedras, PR · On-site

$17.50 - $21/hr

Manufacturing Operator Upstream What we do At Kenvue, we realize the extraordinary power of everyday care. Built on over a century of heritage and rooted in science, we're the house of iconic brands ...

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How much do upstream manufacturing jobs pay per hour?

As of Jun 29, 2026, the average hourly pay for upstream manufacturing in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What is upstream manufacturing?

Upstream manufacturing refers to the initial stages of the production process in industries like biotechnology and pharmaceuticals, where raw materials such as cells, bacteria, or yeast are cultivated to produce a desired product. This stage typically includes activities like cell culture, fermentation, and media preparation. The goal is to optimize the growth and productivity of the biological system to ensure efficient production before moving to downstream processing, which involves purification and formulation of the final product.

What are some common challenges faced in upstream manufacturing, and how are they typically addressed by teams?

In upstream manufacturing, one of the main challenges is maintaining consistent cell culture conditions to optimize yield and product quality. Teams often face issues such as contamination, variability in raw materials, and equipment malfunctions. To address these challenges, upstream teams implement rigorous standard operating procedures (SOPs), utilize real-time monitoring systems, and collaborate closely with quality assurance and process engineering teams. Regular team meetings and cross-functional communication are key to quickly identifying and solving problems, ensuring smooth production runs.

What are the key skills and qualifications needed to thrive in Upstream Manufacturing, and why are they important?

To thrive in Upstream Manufacturing, you need a solid understanding of bioprocessing, cell culture techniques, and process engineering, often supported by a degree in biotechnology, chemical engineering, or a related field. Familiarity with bioreactors, process control systems, and cGMP regulations is typically required, along with certifications like Six Sigma or Lean Manufacturing being advantageous. Strong analytical thinking, attention to detail, and effective teamwork are essential soft skills for excelling in this field. These capabilities ensure efficient production, product quality, and compliance with industry standards in a highly regulated environment.

What is the difference between Upstream Manufacturing vs Downstream Manufacturing?

AspectUpstream ManufacturingDownstream Manufacturing
FocusRaw material extraction and initial processingFinal product assembly and packaging
Work EnvironmentFactories, extraction sitesAssembly lines, packaging facilities
CredentialsTechnical certifications, safety trainingQuality control, packaging certifications
Industry UsageOil & gas, chemicals, miningPharmaceuticals, food production, consumer goods

Upstream Manufacturing involves the extraction and initial processing of raw materials, while Downstream Manufacturing focuses on transforming these materials into finished products. Both roles are essential in the supply chain but differ in their processes, environments, and required skills.

More about Upstream Manufacturing jobs
What are the most commonly searched types of Upstream Manufacturing jobs? The most popular types of Upstream Manufacturing jobs are:
What states have the most Upstream Manufacturing jobs? States with the most job openings for Upstream Manufacturing jobs include:
What job categories do people searching Upstream Manufacturing jobs look for? The top searched job categories for Upstream Manufacturing jobs are:
Upstream Manufacturing jobs near you
Infographic showing various Upstream Manufacturing job openings in the United States as of June 2026, with employment types broken down into 89% Full Time, 6% Part Time, 3% Contract, and 2% Nights. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $51,890 per year, or $24.9 per hour.
Additive Manufacturing Technician

Additive Manufacturing Technician

Lockheed Martin Corporation

Grand Prairie, TX

Other

Posted 2 days ago

Lockheed Martin rating

8.2

Company rating: 8.2 out of 10

Based on 387 frontline employees who took The Breakroom Quiz

30th of 60 rated aerospace companies

Job description

You will be the Additive Manufacturing Technician for the Advanced Manufacturing Technologies team. Our team is responsible for operating and optimizing highperformance additivemanufacturing processes.


What You Will Be Doing


As the Additive Manufacturing Technician you will be responsible for running, maintaining, and improving critical furnace and machine operations that enable largescale metaladditive production.


Your responsibilities will include, but are not limited to:



  • Run and maintain the solar vacuum furnace, including stressrelief and aging profiles.

  • Run and maintain the AIP HIP furnace for multiple material sets.

  • Build and resurface largescale additive build plates, including EDM, surface grinding, and full inspection.

  • Operate and service two largescale additive machines across two material families.

  • Provide job, consumable, and cost updates to customers and leadership while partnering with downstream and upstream manufacturing functions.


Why Join Us


The ideal candidate is a handson problemsolver who thrives in fastpaced, highimpact environments. You will work directly with crossfunctional manufacturing teams, see your work translate into tangible production outcomes, and grow within a culture that rewards technical mastery.


We are committed to supporting your worklife balance and overall wellbeing, offering flexible scheduling options. Learn more about Lockheed Martin's comprehensive benefits package here.


Further Information About This Opportunity


This position is in Dallas. Discover more about our Dallas, Texas location.


MUST BE A U.S. CITIZEN - This position is located at a facility that requires special access.

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About Lockheed Martin

Sourced by ZipRecruiter

As a global security and aerospace company, the majority of Lockheed Martin's business is with the U.S. Department of Defense and U.S. federal government agencies.The remaining portion of Lockheed Martin's business is comprised of international government and commercial sales of products, services and platforms.

Industry

Manufacturing

Company size

10,000+ Employees

Headquarters location

Bethesda, MD, US

Year founded

1912

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