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Transgenic Mouse Jobs (NOW HIRING)

MD Anderson

Research Assistant I - Symptom Research

Houston, TX · On-site

$18.25 - $25.25/hr

They are organized, safety-conscious, and comfortable managing routine responsibilities such as transgenic mouse colony maintenance while maintaining thorough documentation of experimental procedures ...

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How much do transgenic mouse jobs pay per hour?

As of Jun 7, 2026, the average hourly pay for transgenic mouse in the United States is $29.85, according to ZipRecruiter salary data. Most workers in this role earn between $27.40 and $31.01 per hour, depending on experience, location, and employer.

What is a Transgenic Mouse job?

A Transgenic Mouse job typically involves working with genetically modified mice in a research setting. Scientists or technicians in this role create, maintain, and study mice with specific genetic modifications to understand gene functions and model human diseases. Responsibilities may include breeding, genotyping, performing procedures, and analyzing data. These roles are crucial in biomedical research, drug development, and genetics studies.

What are the key skills and qualifications needed to thrive as a Transgenic Mouse Technician, and why are they important?

To thrive as a Transgenic Mouse Technician, you need expertise in animal handling, knowledge of genetics and breeding, and often a scientific degree in biology or a related field. Familiarity with laboratory management systems, PCR, and genotyping tools is typically required, along with certification in animal care (e.g., AALAS certification). Strong attention to detail, problem-solving skills, and effective communication are essential soft skills for managing complex breeding programs and collaborating with research teams. These combined skills ensure accurate genetic experiments, animal welfare, and successful support of research objectives.

What are some common challenges faced by researchers working with transgenic mouse models, and how can they be addressed?

Researchers working with transgenic mouse models often encounter challenges related to genetic variability, breeding complexities, and maintaining colony health. Managing unexpected phenotypic outcomes or off-target genetic effects requires careful experimental planning and rigorous genotyping protocols. Collaboration with experienced animal care staff and geneticists, along with thorough documentation and adherence to ethical guidelines, can help ensure robust experimental results and animal welfare.

What is the difference between Transgenic Mouse vs Laboratory Animal Technician?

AspectTransgenic MouseLaboratory Animal Technician
Required CredentialsAdvanced degrees in genetics or molecular biology, specialized training in genetic modificationHigh school diploma or associate degree, training in animal care and handling
Work EnvironmentResearch laboratories focused on genetic engineering and biomedical researchAnimal care facilities, research labs, veterinary settings
Employer & IndustryBiotech companies, research institutions, universitiesResearch institutions, pharmaceutical companies, animal research facilities

Transgenic Mouse specialists focus on creating and maintaining genetically modified mice for research, requiring advanced genetics knowledge. Laboratory Animal Technicians provide daily care and handling of animals, including transgenic mice, but with less emphasis on genetic modification. Both roles are essential in biomedical research but differ in technical complexity and responsibilities.

What are transgenic mice?

Transgenic mice are laboratory mice that have had foreign genes deliberately inserted into their genome through genetic engineering techniques. These mice are commonly used in biomedical research to study gene function, model human diseases, and test potential treatments. By introducing specific genes, scientists can observe the effects and gain insights into genetic disorders, cancer, and other health conditions. Transgenic mice have become invaluable tools for advancing medical research and drug development.
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Transgenic Mouse jobs near you
Infographic showing various Transgenic Mouse job openings in the United States as of May 2026, with employment types broken down into 6% As Needed, 6% Full Time, 76% Part Time, 6% Temporary, and 6% Contract. Highlights an 22% Physical, and 78% Remote job distribution, with an average salary of $62,081 per year, or $29.8 per hour.

Scientist I or II, In Vivo Pharmacology, Drug Discovery

ALS TDI

Watertown, MA • On-site

$100K - $110K/yr

Full-time

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

About the ALS Therapy Development Institute

The ALS Therapy Development Institute (ALS TDI) is the world's leading nonprofit biotech focused exclusively on discovering and developing effective treatments for amyotrophic lateral sclerosis (ALS). Our multidisciplinary team integrates in vivo pharmacology, molecular biology, and clinical insights to accelerate ALS therapy development from bench to bedside.

Position Summary

We are seeking a highly motivated scientist to join our preclinical pharmacology team. The successful candidate will bring a broad and robust technical skill set largely focused on in vivo techniques. This position is responsible for developing new animal models of ALS and performing preclinical pharmacology studies to evaluate the safety, efficacy, and mechanism of action of experimental drugs.

Key Responsibilities

  • Design, execute, and interpret pharmacology studies including tolerability, PK/PD, and efficacy to evaluate therapeutic candidates.
  • Perform aseptic surgical procedures in rodents such as stereotaxic ICV and intrathecal injections and osmotic pump implantations.
  • Develop and conduct phenotypic, behavioral, and functional assays to assess drug efficacy and characterize disease progression.
  • Generate and characterize novel ALS models using transgenic approaches, viral vectors, and CRISPR-based genome editing
  • Design and manage transgenic mouse breeding strategies to investigate genetic interactions.
  • Write grant proposals, manuscripts, presentations, and reports to communicate experimental findings.
  • Prepare and maintain standard operating procedures (SOPs) and ensure all studies comply with IACUC, animal welfare, and biosafety requirements.
  • Mentor and train junior staff in experimental techniques, data analysis, and scientific problem solving.
  • Stay current with emerging scientific advances in the ALS field and proactively share insights and new methodologies with the team.

Qualifications

Required

  • PhD in neuroscience, pharmacology, molecular biology, or related field
  • Strong publication record with at least two first-author papers
  • Hands on experience with rodent models, behavioral assays, and stereotaxic surgery
  • Background in mouse model development, transgenic strategies, or genetic engineering
  • Strong foundation in experimental design and statistical analysis
  • Excellent written and verbal communication skills

Strongly Preferred

  • Postdoctoral or industry experience in drug discovery or translational research
  • Work in ALS or related neurodegenerative diseases
  • Experience with transgenic colony management, genotyping, and breeding strategies
  • Experience with histology, immunohistochemistry, or imaging-based analyses
  • Proficiency in standard molecular and biochemical techniques like Western blot, PCR, ELISA, etc.

Nice to Have

  • Work with non-rodent models (zebrafish, Drosophila, C. elegans)
  • Exposure to gene therapy, antisense oligonucleotides, or biologics
  • Familiarity with pharmacology studies and drug discovery workflows
  • Proficiency with coding and AI based tools
  • Experience mentoring junior scientists or supervising small teams.

What We Offer

  • A mission-driven environment focused on accelerating therapies for ALS patients.
  • A collaborative, cross-functional research setting with access to advanced technology platforms.
  • A competitive salary and benefits package commensurate with experience and level.
  • Opportunities for scientific growth and contribution to high-impact research.

Job Posted by ApplicantPro