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Enzyme Purification Jobs (NOW HIRING)

Cascade Bio

Laboratory Analyst

Denver, CO · On-site

$50K - $60K/yr

Response for enzyme expression, purification, and characterization using standard systems, including E. coli and IMAC. Assist with maintenance of laboratory-scale bioreactor and scale up activities ...

Cascade Biocatalysts

Laboratory Analyst

Denver, CO · On-site

$50K - $60K/yr

Response for enzyme expression, purification, and characterization using standard systems, including E. coli and IMAC. Assist with maintenance of laboratory-scale bioreactor and scale up activities ...

Cascade Bio

Laboratory Analyst

Denver, CO

Response for enzyme expression, purification, and characterization using standard systems, including E. coli and IMAC. Assist with maintenance of laboratory-scale bioreactor and scale up activities ...

AA2IT

Protein Engineer I , II

Richmond, VA

$34/hr

Experience working with protein purification • Recombinant protein production and purification ... Experience working with enzymes and peptides * Experience in method development and method transfer

New

AA2IT

Protein Engineer I , II

Elkton, VA

$34/hr

Experience working with protein purification • Recombinant protein production and purification ... Experience working with enzymes and peptides * Experience in method development and method transfer

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Enzyme Purification information

What are the key skills and qualifications needed to thrive as an Enzyme Purification Specialist, and why are they important?

To thrive as an Enzyme Purification Specialist, you need a solid background in biochemistry or molecular biology, experience with protein purification techniques, and often a relevant bachelor's or advanced degree. Familiarity with chromatography systems (such as HPLC or FPLC), spectrophotometers, and analytical software is typically required. Attention to detail, problem-solving abilities, and effective communication are soft skills that help ensure accuracy and collaboration. These skills are crucial for producing high-purity enzymes efficiently, ensuring reproducible results, and supporting research or manufacturing objectives.

What are some common challenges faced in enzyme purification roles, and how can they be addressed?

Professionals in enzyme purification often encounter challenges such as maintaining enzyme stability during extraction and purification, optimizing yield without compromising activity, and troubleshooting issues like protein aggregation or contamination. These challenges can be addressed by staying current with the latest techniques, regularly calibrating equipment, and collaborating closely with analytical and upstream processing teams. Effective communication and documentation are also crucial for resolving issues quickly and ensuring reproducibility in large-scale or GMP environments.

What is enzyme purification?

Enzyme purification is the process of isolating a specific enzyme from a complex mixture, such as a cell extract, to obtain it in a highly pure form. This typically involves a series of steps like centrifugation, filtration, precipitation, and chromatography to separate the enzyme from other proteins and contaminants. Purified enzymes are essential for research, industrial applications, and the development of diagnostic or therapeutic products.

What is the difference between Enzyme Purification vs Protein Purification?

AspectEnzyme PurificationProtein Purification
CredentialsBiochemist, Molecular BiologistBiochemist, Molecular Biologist
Work EnvironmentLaboratories, biotech companiesLaboratories, biotech companies
Industry UsageEnzyme isolation for research and industrial useGeneral protein isolation for various applications
FocusIsolating and characterizing specific enzymesIsolating and analyzing diverse proteins

Enzyme Purification specifically involves isolating enzymes for research or industrial purposes, focusing on their activity and function. Protein Purification covers a broader range of proteins, including enzymes, structural proteins, and antibodies. While both roles require similar skills and work environments, enzyme purification emphasizes enzyme activity assays, whereas protein purification involves diverse techniques for different protein types.

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Enzyme Purification jobs near you
Infographic showing various Enzyme Purification job openings in the United States as of May 2026, with employment types broken down into 78% Full Time, 11% Part Time, and 11% Contract. Highlights an 92% In-person, 3% Hybrid, and 5% Remote job distribution.

Laboratory Analyst

Cascade Bio

Denver, CO • On-site

$50K - $60K/yr

Full-time

Posted 9 days ago

Job description

Job Description:

Cascade Bio is a fast-moving early-stage startup seeking a motivated and detail-oriented Laboratory Analyst to support enzyme purification, quality control, and laboratory operations. This is an exciting opportunity to work at the intersection of biocatalysis, materials science, and sustainable technology while contributing directly to the development of next-generation enzyme immobilization.
We are looking for an analyst who embodies our core values: an obsession with delivering top-caliber products to customers, active curiosity, consistent communication, and an inherent assumption of goodwill. The ideal candidate shares Cascade's vision of empowering enzymes to disrupt the chemical industry and is motivated to translate our science into impactful, sustainable technology. This is an on-site position at our laboratory in Denver, CO.

Key Responsibilities:

  • Biocatalysis: Perform routine biochemical assays, including enzyme activity and protein concentration measurements.
  • Protein expression: Response for enzyme expression, purification, and characterization using standard systems, including E. coli and IMAC. Assist with maintenance of laboratory-scale bioreactor and scale up activities as needed.
  • Data collection and analysis: Accurately record experimental procedures, observations, and results.
  • Attention to detail: Follows standard operating procedures (SOPs) to ensure consistency, traceability, and data integrity. Maintain accurate inventory of chemicals, enzymes, and supplies.
  • Teamwork: Collaborate with cross-functional teams, including our Associate Director of Chemistry and Enzyme Scientists.
  • Communication: Communicates project status, results, and technical issues clearly and promptly to supervisor and team.
  • Laboratory maintenance: Maintain cleanliness and organization of the laboratory space. Assist with maintenance and calibration of laboratory equipment.

Qualifications:

Required:

  • Bachelor's degree in Biological Engineering, Chemical Engineering, Biology, Chemistry, or a related scientific field
  • 12 years of hands-on wet lab experience in academic or industry settings
  • Proficiency in fundamental laboratory techniques and good laboratory practices
  • Strong attention to detail and commitment to accurate documentation
  • Excellent organizational and time management skills
  • Commitment to laboratory safety and maintaining a safe working environment
  • Proactive approach to troubleshooting experimental issues and proposing innovative solutions
  • Strong teamwork skills with the ability to collaborate with multidisciplinary teams

Preferred:

  • Experience with protein purification or enzyme-related workflows
  • Familiarity with chromatography systems and biochemical assays
  • Knowledge of process development or protein expression scale-up
  • Previous experience in a fast-paced startup environment

Cascade Bio is an equal opportunity employer. We welcome and encourage diversity in the workplace and strongly encourage candidates from all backgrounds to apply.

At Cascade Biocatalysts, we are commercializing our Body Armor for Enzymes, a polymer science innovation that makes enzymes rugged and reliable for cost-effective biomanufacturing. Our platform unlocks the power of enzymes to replace traditional, unsustainable chemical processes and supports the buildout of a resilient and clean chemical industry.

We are a small and growing team, passionate about bridging biology and chemistry to build the future of manufacturing. If you're excited to bring enzymes out of the lab and into the world we'd like to meet you.

Salary Range: $50,000 - $60,000