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Enzyme Purification Jobs (NOW HIRING)

UAB

RESEARCHER II

Tampa, FL · On-site

$19.23/hr

Specifically, we focus on the DNA repair enzyme Tyrosyl-DNA phosphodiesterase I (Tdp1) and ... isolation/purification, cellular toxicity, growth assays and mitochondrial assays. General ...

UAB NOVA RENT

RESEARCHER II

Birmingham, AL · On-site

$19.23/hr

Specifically, we focus on the DNA repair enzyme Tyrosyl-DNA phosphodiesterase I (Tdp1) and ... isolation/purification, cellular toxicity, growth assays and mitochondrial assays. General ...

University of Utah

Research Technicians

Campus, IL

$18 - $20/hr

Hobbs Learn advanced recombinant protein expression and purification techniques. Maintain stocks of common laboratory proteins including polymerase and protease enzymes. Pursue an individual research ...

University of Utah

Research Technicians

Campus, IL

$18 - $20/hr

Hobbs Learn advanced recombinant protein expression and purification techniques. Maintain stocks of common laboratory proteins including polymerase and protease enzymes. Pursue an individual research ...

University of Utah

Research Technicians

Campus, IL

$18 - $20/hr

Hobbs Learn advanced recombinant protein expression and purification techniques. Maintain stocks of common laboratory proteins including polymerase and protease enzymes. Pursue an individual research ...

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Enzyme Purification information

What are the key skills and qualifications needed to thrive as an Enzyme Purification Specialist, and why are they important?

To thrive as an Enzyme Purification Specialist, you need a solid background in biochemistry or molecular biology, experience with protein purification techniques, and often a relevant bachelor's or advanced degree. Familiarity with chromatography systems (such as HPLC or FPLC), spectrophotometers, and analytical software is typically required. Attention to detail, problem-solving abilities, and effective communication are soft skills that help ensure accuracy and collaboration. These skills are crucial for producing high-purity enzymes efficiently, ensuring reproducible results, and supporting research or manufacturing objectives.

What are some common challenges faced in enzyme purification roles, and how can they be addressed?

Professionals in enzyme purification often encounter challenges such as maintaining enzyme stability during extraction and purification, optimizing yield without compromising activity, and troubleshooting issues like protein aggregation or contamination. These challenges can be addressed by staying current with the latest techniques, regularly calibrating equipment, and collaborating closely with analytical and upstream processing teams. Effective communication and documentation are also crucial for resolving issues quickly and ensuring reproducibility in large-scale or GMP environments.

What is enzyme purification?

Enzyme purification is the process of isolating a specific enzyme from a complex mixture, such as a cell extract, to obtain it in a highly pure form. This typically involves a series of steps like centrifugation, filtration, precipitation, and chromatography to separate the enzyme from other proteins and contaminants. Purified enzymes are essential for research, industrial applications, and the development of diagnostic or therapeutic products.

What is the difference between Enzyme Purification vs Protein Purification?

AspectEnzyme PurificationProtein Purification
CredentialsBiochemist, Molecular BiologistBiochemist, Molecular Biologist
Work EnvironmentLaboratories, biotech companiesLaboratories, biotech companies
Industry UsageEnzyme isolation for research and industrial useGeneral protein isolation for various applications
FocusIsolating and characterizing specific enzymesIsolating and analyzing diverse proteins

Enzyme Purification specifically involves isolating enzymes for research or industrial purposes, focusing on their activity and function. Protein Purification covers a broader range of proteins, including enzymes, structural proteins, and antibodies. While both roles require similar skills and work environments, enzyme purification emphasizes enzyme activity assays, whereas protein purification involves diverse techniques for different protein types.

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Enzyme Purification jobs near you
Infographic showing various Enzyme Purification job openings in the United States as of May 2026, with employment types broken down into 78% Full Time, 11% Part Time, and 11% Contract. Highlights an 92% In-person, 3% Hybrid, and 5% Remote job distribution.
RESEARCHER II

RESEARCHER II

UAB

Tampa, FL • On-site

$19.23/hr

Other

Posted 17 days ago

UAB Medicine rating

7.4

Company rating: 7.4 out of 10

Based on 181 frontline employees who took The Breakroom Quiz

248th of 864 rated healthcare providers

Job description

Position Summary

The University of Alabama at Birmingham, the Van Waardenburg lab in the Department of Biochemistry and Molecular Genetics, has an immediate opening for a Researcher II. We investigate enzyme mechanisms, at structural, biochemical and cellular levels using human and yeast cell models and eukaryotic enzyme orthologs. Specifically, we focus on the DNA repair enzyme Tyrosyl-DNA phosphodiesterase I (Tdp1) and cytosolic sulfotransferases (SULTs). The technician responsibilities will include biochemical and cellular assays, such as protein isolation/purification, cellular toxicity, growth assays and mitochondrial assays.

General Responsibilities

  • Under minimal supervision, to set up and perform routine and established lab procedures in support of lab goals.

  • To collect, enter and summarize data.

  • To monitor results and report unusual outcomes.

  • Performs other duties as assigned.

Hourly Range:   $ 15.50- $19.23

Qualifications

Bachelor's degree in related field OR Associate's degree in related field and two (2) years of related experience OR High School diploma or GED and four (4) years of related experience required. Work experience may NOT substitute for education requirement.

Preferences

  • Experience in mammalian cell culture, molecular biology and affinity for biochemical analysis are preferred. 

Key Skills

  • Written and verbal communication skills

  • Interpersonal skills

  • Ability to work as part of a team 
     

UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.

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