CRA 2, Oncology, IQVIA Biotech
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
Durham, NC · On-site
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
New
CRA 2, Oncology, IQVIA Biotech
Durham, NC · On-site
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
New
Senior Clinical Research Associate, Early Clinical Development
Durham, NC · On-site
$87K - $169K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
Senior Clinical Research Associate, Early Clinical Development
Durham, NC · On-site
$87K - $169K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
Durham, NC · On-site
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA Biotech
Durham, NC · On-site
$74K - $175K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
CRA 2, Oncology, IQVIA
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
CRA 2, Oncology, IQVIA
Durham, NC · On-site
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
CRA 2, Oncology, IQVIA
Durham, NC · On-site
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
Senior Clinical Research Associate, Early Clinical Development
Durham, NC · On-site
$87K - $169K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
Senior Clinical Research Associate, Early Clinical Development
Durham, NC · On-site
$87K - $169K/yr
... TMF) and the Investigator Site File (ISF) in accordance with regulatory standards. * Document site management activities, visit outcomes, and follow-up actions through detailed reports and ...
CRA 2, Oncology, IQVIA
Durham, NC · On-site
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
CRA 2, Oncology, IQVIA
Durham, NC · On-site
$87K - $145K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Maintain governance and oversee TMF compliance. * Drive adoption of modern technologies, standards ... Collaborate cross‑functionally and manage data access appropriately. * Support regulatory ...
Maintain governance and oversee TMF compliance. * Drive adoption of modern technologies, standards ... Collaborate cross‑functionally and manage data access appropriately. * Support regulatory ...
Clinical Research Associate, Sponsor Dedicated
Durham, NC · On-site
$71K - $189K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Clinical Research Associate, Sponsor Dedicated
Durham, NC · On-site
$71K - $189K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Sr. Clinical Research Associate, IQVIA
$87K - $169K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Sr. Clinical Research Associate, IQVIA
$87K - $169K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Maintain governance and oversee TMF compliance. Strategy & Innovation * Drive adoption of modern ... Collaborate cross-functionally and manage data access appropriately. * Support regulatory ...
Maintain governance and oversee TMF compliance. Strategy & Innovation * Drive adoption of modern ... Collaborate cross-functionally and manage data access appropriately. * Support regulatory ...
Clinical Research Associate, Sponsor Dedicated
$71K - $189K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Clinical Research Associate, Sponsor Dedicated
$71K - $189K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Clinical Research Associate, Full Service
Durham, NC · On-site
$49K - $175K/yr
Job Overview Perform monitoring and site management work to ensure that sites are conducting the ... File (TMF) verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...
Clinical Research Associate, Full Service
Durham, NC · On-site
$49K - $175K/yr
Job Overview Perform monitoring and site management work to ensure that sites are conducting the ... File (TMF) verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...
Clinical Research Associate - Sponsor Dedicated
Durham, NC · On-site
$87K - $182K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Clinical Research Associate - Sponsor Dedicated
Durham, NC · On-site
$87K - $182K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Maintain governance and oversee TMF compliance. Strategy & Innovation * Drive adoption of modern ... Collaborate cross-functionally and manage data access appropriately. * Support regulatory ...
Maintain governance and oversee TMF compliance. Strategy & Innovation * Drive adoption of modern ... Collaborate cross-functionally and manage data access appropriately. * Support regulatory ...
Sr. Clinical Research Associate, IQVIA
Durham, NC · On-site
$87K - $169K/yr
Perform monitoring and site management work to ensure that sites are conducting the study(ies) and ... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and ...
Sr. Clinical Research Associate, IQVIA
Durham, NC · On-site
$87K - $169K/yr
Perform monitoring and site management work to ensure that sites are conducting the study(ies) and ... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and ...
Sr. Clinical Research Associate, IQVIA
$87K - $169K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Sr. Clinical Research Associate, IQVIA
$87K - $169K/yr
... TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP and local regulatory requirements. Create and maintain appropriate documentation regarding site management ...
Tmf Manager information
See Raleigh, NC salary details
$28.04 - $33.99
4% of jobs
$33.99 - $39.93
6% of jobs
$39.93 - $45.88
7% of jobs
$50.34 is the 25th percentile. Wages below this are outliers.
$45.88 - $51.83
9% of jobs
$51.83 - $57.78
15% of jobs
The median wage is $60.40 / hr.
$57.78 - $63.73
18% of jobs
$67.96 is the 75th percentile. Wages above this are outliers.
$63.73 - $69.67
21% of jobs
$69.67 - $75.62
7% of jobs
$75.62 - $81.57
6% of jobs
$81.57 - $87.52
3% of jobs
$87.52 - $93.46
2% of jobs
$28
$60
$93
How much do tmf manager jobs pay per hour?
As of Sep 14, 2026, the average hourly pay for tmf manager in Raleigh, NC is $60.77, according to ZipRecruiter salary data. Most workers in this role earn between $49.28 and $68.46 per hour, depending on experience, location, and employer.
What is a TMF Manager?
A TMF (Trial Master File) Manager is responsible for overseeing the management, maintenance, and compliance of clinical trial documentation. They ensure that the TMF is accurate, complete, and inspection-ready in accordance with regulatory requirements, such as ICH-GCP and FDA guidelines. TMF Managers collaborate with clinical teams, quality assurance, and regulatory authorities to support audit and inspection activities. Their role is critical in ensuring data integrity and regulatory compliance throughout the clinical trial lifecycle.
What are the key skills and qualifications needed to thrive as a TMF Manager?
To excel as a TMF Manager (Trial Master File Manager), you need a solid understanding of clinical trial documentation, GCP (Good Clinical Practice) guidelines, and regulatory requirements—typically supported by a degree in life sciences or a related field. Familiarity with electronic TMF (eTMF) systems, document management software, and relevant industry certifications such as RAC or DIA TMF certificates is important. Exceptional attention to detail, organizational skills, and the ability to communicate effectively across cross-functional teams distinguish top TMF Managers. These competencies are essential for ensuring the integrity, completeness, and audit-readiness of clinical trial documentation throughout the study lifecycle.
What are some typical challenges a TMF Manager might face in their role?
TMF Managers often encounter challenges such as ensuring consistent TMF document quality across multiple studies, meeting tight regulatory submission deadlines, and facilitating communication among global project teams. Keeping the TMF up to date and audit-ready requires strong organizational skills and proactive problem-solving, as studies can involve large volumes of documentation and frequent protocol amendments. Effective TMF Managers routinely collaborate with clinical, regulatory, and quality assurance teams to ensure document accuracy and regulatory compliance. Overcoming these challenges is key to maintaining smooth clinical trial operations and supporting successful regulatory inspections.
What are the most commonly searched types of Tmf jobs in Raleigh, NC?
The most popular types of Tmf jobs in Raleigh, NC are:
What are popular job titles related to Tmf Manager jobs in Raleigh, NC?
For Tmf Manager jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Tmf Manager jobs in Raleigh, NC look for?
The top searched job categories for Tmf Manager jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Tmf Manager jobs?
Cities near Raleigh, NC with the most Tmf Manager job openings:
CRA 2, Oncology, IQVIA Biotech
Durham, NC
IQVIA
• Health Care and Social Assistance • 10K+ employees10,000+ employees
$74K - $175K/yr
Full-time
Posted 10 days ago
IQVIA rating
8.1
Based on 53 frontline employees who took The Breakroom Quiz
Job description
IQVIA Biotech is expanding our Clinical Monitoring team and is seeking CRA 2 professionals with a minimum of 1 year of on-site monitoring experience and oncology solid tumor monitoring experience.
IQVIA Biotech is a full-service CRO purpose-built to serve biotech sponsors. With over 25 years of experience, we offer agile, therapeutically aligned solutions and trusted partnerships that help bring breakthrough treatments to patients faster.
Job Overview
We are seeking a dedicated Clinical Research Associate (CRA) to join our team and play a key role in ensuring the successful execution of clinical trials. In this position, you will be responsible for monitoring and managing clinical sites to ensure compliance with study protocols, regulatory requirements, and sponsor expectations. Your work will directly contribute to the integrity and quality of clinical research data.
Key Responsibilities
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Conduct all types of site visits-selection, initiation, monitoring, and close-out in alignment with the contracted scope of work, Good Clinical Practice (GCP), and ICH guidelines.
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Collaborate with site staff to implement and track subject recruitment strategies that align with project timelines and enrollment goals.
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Deliver protocol and study-specific training to site personnel and maintain consistent communication to manage expectations and resolve issues.
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Assess site performance and adherence to the protocol, escalating quality concerns as needed to ensure compliance and data integrity.
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Monitor study progress by tracking regulatory submissions, subject enrollment, case report form (CRF) completion, and resolution of data queries.
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Ensure that essential documents are collected and maintained in both the Trial Master File (TMF) and the Investigator Site File (ISF) in accordance with regulatory standards.
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Document site management activities, visit outcomes, and follow-up actions through detailed reports and correspondence.
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Work closely with cross-functional project teams to support study execution and ensure alignment with project goals.
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Depending on the project, you may also support site-level recruitment planning and financial management, including invoice collection and budget tracking.
Qualifications
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Bachelor's degree in life sciences or health-related field (or equivalent experience).
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Requires at least 1 year of on-site monitoring experience.
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Strong understanding of GCP, ICH guidelines, and regulatory requirements.
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Ability to travel as required by the project.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more athttps://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $74,500.00 - $175,100.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.
About IQVIA
Sourced by ZipRecruiter
At IQVIA, we are passionate about helping customers and partners improve results and patient outcomes. Everything we do contributes to this vision for creating a healthier world. In today’s healthcare environment, it’s not only about how much data, information, and technology you have at your fingertips – it’s what you do with it. IQVIA is focused on making intelligent connections for customers across the entire healthcare ecosystem to help you drive healthcare forward. Whether that means partnering with novel technology companies to boost patient engagement, leveraging AI & machine learning to accelerate results, or using decentralized trials to reach the right patients wherever they are – we are always looking for smarter ways to move you forward.
Industry
Health care and social assistance
Company size
10,000+ Employees
Headquarters location
Durham, NC, US