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Sub Investigator Jobs (NOW HIRING)

Medix

Sub-Investigator

Plant City, FL · On-site

$65 - $80/hr

Job Summary Our client is seeking a Sub-Investigator to join their team. The primary responsibility of this role is to collaborate on clinical trials, conducting physical exams, medical histories ...

Ergclinical

Sub-Investigator

Rogers, AR · On-site

$75 - $85/hr

The Sub-Investigator acts as the secondary physician in charge of medical and clinical issues at the clinical research site, acting in place of the Principal Investigator, as requested, or required.

K2 Staffing LLC

Sub-Investigator

Tampa, FL · On-site

$43K - $44K/yr

The Sub Investigator promotes Good Clinical Practice in the conduct of clinical investigations by ensuring adherence to protocol requirements, protecting the rights and welfare of study subjects ...

Evolution Research Group

Sub-Investigator

Rogers, AR · On-site

$150K - $175K/yr

The Sub-Investigator acts as the secondary physician in charge of medical and clinical issues at the clinical research site, acting in place of the Principal Investigator, as requested, or required.

Evolution Research Group

Sub-Investigator

Rogers, AR · On-site

$75 - $85/hr

The Sub-Investigator acts as the secondary physician in charge of medical and clinical issues at the clinical research site, acting in place of the Principal Investigator, as requested, or required.

Ergclinical

$75 - $85/hr

The Sub-Investigator acts as the secondary physician in charge of medical and clinical issues at the clinical research site, acting in place of the Principal Investigator, as requested, or required.

Medix

Sub-Investigator

San Diego, CA · On-site

$62.50 - $72.12/hr

Job Summary Our client is seeking a dedicated Sub-Investigator to lead and oversee clinical trials, ensuring adherence to protocol requirements, regulatory standards, and ethical guidelines. The ...

Medix

Sub-Investigator

Austin, TX · On-site

$74.52 - $85.10/hr

Job Summary Our client is seeking a dedicated Sub-Investigator to join their team with an expertise in clinical trial assessments and psyciatric diagnostic. This role focuses on administering ...

Velocity-Clinical-Research,-Inc.

Sub Investigator

Norfolk, NE · On-site

$45K - $46K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

Medix

Sub-Investigator

La Vergne, TN · On-site

$76.92 - $144.23/hr

Job Summary Our client is seeking a Sub-Investigator responsible for conducting study visits, including medical assessments and ensuring compliance with study protocols. The focus will be on ...

Velocity Clinical Research, Inc.

Sub Investigator

Norfolk, NE · On-site

$45K - $46K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

Velocity Clinical Research, Inc.

Sub Investigator

Norfolk, NE · On-site

$45K - $46K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract - 6 months with the possibility to go perm We're seeking an ...

Care Access

Travel Sub-Investigator

$47K - $48K/yr

Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract - 6 months with the possibility to go perm We're seeking an ...

Pinnacle Clinical Research

Sub-Investigator

San Antonio, TX · On-site

$40K - $40K/yr

Summary: The Clinical Research Nurse Practitioner/Physician Associate will be listed as a sub-investigator on all ongoing study protocols. She/He will be a key member of the team and will be ...

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$32K

$75.3K

$131K

How much do sub investigator jobs pay per year?

As of Sep 15, 2026, the average yearly pay for sub investigator in the United States is $75,325.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $98,500.00 per year, depending on experience, location, and employer.

What is a sub investigator?

A Sub Investigator (Sub-I) is a clinical research professional who assists the Principal Investigator (PI) in conducting clinical trials. They ensure that studies comply with regulatory requirements, oversee patient care, and manage data collection. Sub-Is may perform medical evaluations, review patient histories, and ensure study protocols are followed. Their role is essential in maintaining the integrity of a clinical trial while ensuring participant safety.

What are the typical responsibilities of a sub investigator during a clinical trial?

As a Sub Investigator, you will assist the Principal Investigator in overseeing the day-to-day conduct of clinical trials, which includes monitoring study participants, ensuring protocol adherence, and maintaining accurate study documentation. You may conduct physical exams, review laboratory results, and report adverse events while ensuring all regulatory and ethical guidelines are followed. Collaboration is frequent, both with study coordinators and other research staff, to maintain trial quality and participant safety. This hands-on involvement allows you to gain valuable experience in clinical research operations, often serving as a foundation for upward career mobility.

What are the key skills and qualifications needed to thrive as a sub investigator?

To thrive as a Sub Investigator, you need a background in clinical research, attention to detail, and knowledge of Good Clinical Practice (GCP) guidelines, often supported by a relevant healthcare or scientific degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification is beneficial. Strong organizational skills, teamwork, and clear written and verbal communication help set candidates apart. These capabilities are crucial for ensuring regulatory compliance, accurate study documentation, and effective coordination with principal investigators and research teams.

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Sub Investigator jobs near you
Infographic showing various Sub Investigator job openings in the United States as of September 2026, with employment types broken down into 2% As Needed, 86% Full Time, 9% Part Time, 2% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $75,325 per year, or $36.2 per hour.

Sub-Investigator

Plant City, FL • On-site

Medix
Recruiting and Staffing Services • 1 - 5K employees
Learn more about Medixexternal

$65 - $80/hr

Part-time

Medical, Dental, Vision, Retirement

Re-posted 17 days ago

Key responsibilities

  • Perform protocol-specified physical exams, medical histories, and study visits.

  • Assess eligibility criteria and co-sign source documentation with the Principal Investigator (PI).

  • Order and interpret labs and diagnostics per study requirements.

Job description

You are applying for a position through Medix, a staffing agency. The actual posting represents a position at one of our clients.
Job Summary
Our client is seeking a Sub-Investigator to join their team. The primary responsibility of this role is to collaborate on clinical trials, conducting physical exams, medical histories, and study visits. The position involves ordering and interpreting labs, counseling participants, and maintaining compliance with Good Clinical Practice (GCP).
Key Responsibilities
  • Perform protocol-specified physical exams, medical histories, and study visits.
  • Assess eligibility criteria and co-sign source documentation with the Principal Investigator (PI).
  • Order and interpret labs and diagnostics per study requirements.
  • Counsel participants on study procedures, investigational products, and adverse-event reporting.
  • Manage and document adverse events (AEs) and serious adverse events (SAEs), escalating them to PI and sponsor as required.
  • Maintain GCP-compliant source notes.
  • Participate in investigator meetings, site initiation visits (SIVs), monitoring visits, and audits.

Qualifications
  • Currently, unrestricted Florida license as NP or PA-C.
  • Excellent communication and interpersonal abilities.
  • Prior experience as a Sub-Investigator or treating provider in clinical trials is preferred.
  • Spanish-speaking (or other community language) is a plus.
  • Phlebotomy and IV skills are preferred.

Schedule/Shift
Monday: Afternoon shift ~ noon - 5pm
Tuesday: 8-5
Wednesday: Off
Thursday: 8-5
Friday: 8-5
Benefits
  • Paid Sick Leave (Medix provides paid sick leave according to state and local sick leave ordinances).
  • Health Benefits / Dental / Vision (Medix offers 6 different health plans: 3 Major Medical Plans, 2 Fixed Indemnity Plans (Standard and Preferred), and 1 Minimum Essential Coverage (MEC) Plan. Eligibility for health benefits is based on verifying that an average of 30 hours per week during the first 4 weeks of the work assignment has been met. If you meet eligibility requirements and take action to enroll, you will be covered no earlier than 60 days into your assignment, depending on plan selection(s)).
  • 401k (Eligible on the first 401k open enrollment date following 6 consecutive months on assignment. 401k Open Enrollment dates are 1/1, 4/1, 7/1, and 10/1).
  • Short Term Disability Insurance.
  • Term Life Insurance Plan.

Required Employment / Compliance Language
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
* We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable federal, state, and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance (FCIHO), Los Angeles Fair Chance Ordinance for Employers (ULAC), The San Francisco Fair Chance Ordinance (FCO), and the California Fair Chance Act (CFCA).
Medix Overview:
With over 20 years of experience connecting organizations with highly qualified professionals, Medix is a leading provider of workforce solutions for clients and candidates across the healthcare, scientific, technology, and government industries. Through our core purpose of positively impacting lives, we're dedicated to creating opportunities for job seekers at some of the nation's top companies. As an award-winning career partner, Medix is committed to helping talent find fulfilling and meaningful work because our mission is to help you achieve yours.
* This position is subject to a background check based on its job duties, which may include patient care, working with vulnerable populations, access to financial and confidential information, driving, working with heavy machinery, or working in a warehouse or laboratory environment. Due to these job duties, this position has a significant impact on the business operations and reputation, as well as the safety and well-being of individuals who may be cared for as part of the job position or who may interact with staff or clients.
Medix Staffing Solutions logo

About Medix Staffing Solutions

Sourced by ZipRecruiter

Since 2001, we’ve been dedicated to helping you achieve your goals. Medix was created to become a leading provider of workforce solutions for clients and candidates across the healthcare and life sciences industries. Today, we are that leader. Headquartered in Chicago, we have 23 offices across the United States, and staff talent around the world. Medix is committed to fulfilling our core purpose as an organization: to positively impact the lives of our talent, clients, and teammates through employment, philanthropy, and opportunity. The combination of purpose and values has nurtured our thriving culture that encourages our internal team to excel at work and in everyday life.

Industry

Recruiting and staffing services

Company size

1,001 - 5,000 Employees

Headquarters location

Chicago, IL, US

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