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Sub Investigator Jobs (NOW HIRING)

Care Access

Travel Sub-Investigator

Boston, MA

$50K - $51K/yr

How This Role Makes a Difference The Sub-Investigator will be responsible for travel mixed with remote tele-medicine work to support our clinical research studies.  Additionally, our Sub ...

Altasciences

Sub-Investigator I

Cypress, CA · On-site

$105K - $175K/yr

The Sub-Investigator I will promote Good Clinical Practices (GCP) during the conduct of clinical investigations by ensuring adherence to protocol requirements, protecting the rights and welfare of ...

Altasciences

Sub-Investigator I

Cypress, CA · On-site

$105K - $175K/yr

The Sub-Investigator I will promote Good Clinical Practices (GCP) during the conduct of clinical investigations by ensuring adherence to protocol requirements, protecting the rights and welfare of ...

Atlas Clinical Research

Sub-Investigator, PA

Buffalo, NY · On-site

$110K - $130K/yr

Job Summary The Sub-Investigator, under the supervision of the Principal Investigator, is responsible for both clinical and educational aspects of clinical trial studies while focused on interpreting ...

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$32K

$75.3K

$131K

How much do sub investigator jobs pay per year?

As of Jun 9, 2026, the average yearly pay for sub investigator in the United States is $75,325.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $98,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Sub Investigator position, and why are they important?

To thrive as a Sub Investigator, you need a background in clinical research, attention to detail, and knowledge of Good Clinical Practice (GCP) guidelines, often supported by a relevant healthcare or scientific degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification is beneficial. Strong organizational skills, teamwork, and clear written and verbal communication help set candidates apart. These capabilities are crucial for ensuring regulatory compliance, accurate study documentation, and effective coordination with principal investigators and research teams.

What are some typical responsibilities of a Sub Investigator during a clinical trial?

As a Sub Investigator, you will assist the Principal Investigator in overseeing the day-to-day conduct of clinical trials, which includes monitoring study participants, ensuring protocol adherence, and maintaining accurate study documentation. You may conduct physical exams, review laboratory results, and report adverse events while ensuring all regulatory and ethical guidelines are followed. Collaboration is frequent, both with study coordinators and other research staff, to maintain trial quality and participant safety. This hands-on involvement allows you to gain valuable experience in clinical research operations, often serving as a foundation for upward career mobility.

What is a Sub Investigator job?

A Sub Investigator (Sub-I) is a clinical research professional who assists the Principal Investigator (PI) in conducting clinical trials. They ensure that studies comply with regulatory requirements, oversee patient care, and manage data collection. Sub-Is may perform medical evaluations, review patient histories, and ensure study protocols are followed. Their role is essential in maintaining the integrity of a clinical trial while ensuring participant safety.

More about Sub Investigator jobs
What cities are hiring for Sub Investigator jobs? Cities with the most Sub Investigator job openings:
What are the most commonly searched types of Sub Investigator jobs? The most popular types of Sub Investigator jobs are:
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Sub Investigator jobs near you
Infographic showing various Sub Investigator job openings in the United States as of June 2026, with employment types broken down into 59% Full Time, 32% Part Time, 6% Contract, and 3% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $75,325 per year, or $36.2 per hour.
Travel Sub-Investigator

Travel Sub-Investigator

Care Access

Boston, MA

$50K - $51K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 27 days ago

Job description

About Care Access

Care Access is working to make the future of health better for all. With hundreds of research locations, mobile clinics, and clinicians across the globe, we bring world-class research and health services directly to communities that often face barriers to care. We are dedicated to ensuring that every person has the opportunity to understand their health, access the care they need, and contribute to the medical breakthroughs of tomorrow.

With programs like Future of Medicine, which makes advanced health screenings and research opportunities accessible to communities worldwide, and Difference Makers, which supports local leaders to expand their community health and wellbeing efforts, we put people at the heart of medical progress. Through partnerships, technology, and perseverance, we are reimagining how clinical research and health services reach the world. Together, we are building a future of health that is better and more accessible for all.

To learn more about Care Access, visit www.CareAccess.com.

How This Role Makes a Difference

The Sub-Investigator will be responsible for travel mixed with remote tele-medicine work to support our clinical research studies.  Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational product related reactions, among other duties beyond the standard clinical research Sub-Investigator role. Care Access is looking for highly motivated Nurse Practitioners or Physician's Assistants to support clinical trial related activities in states throughout the USA.

How You'll Make An Impact
  • Work closely with the Principal Investigator to oversee the execution of study protocols, delegating study related duties to site staff, as appropriate, and ensuring site compliance with study protocols, study-specific laboratory procedures, standards of Good Clinical Practice (GCP), Standard Operating Procedures (SOPs), quality (QA/QC) procedures, OSHA guidelines, and other state and local regulations as applicable.
  • Attends and participates in meetings with the director, other managers, and staff as necessary.
  • Complies with regulatory requirements, policies, procedures, and standards of practice.
  • Read and understand the informed consent form, protocol, and investigator's brochure.
  • Be available to see subjects virtually or in-person as dictated by project design, answer their questions, and resolve medical issues during the study visit.
  • Sign and ensure that the study documentation for each study visit is completed.
  • Perform all study responsibilities in compliance with the IRB approved protocol.
  • Administration of Investigational Products (via subcutaneous, transdermal, intramuscular, intravenous, or oral routes).
  • Proficiency in starting, monitoring, and maintaining intravenous lines.
  • Proficiency in phlebotomy, proper blood collection practices, and laboratory processing practices (can be learned)
  • Contribute as an active member of clinician team involved in the management of infusion or other investigational product related reactions.
  • Maintain a clean, efficient clinical area to assure the highest standards of patient care.
  • Follow safety and PPE procedures as well as maintain proper documentation of infusion procedures.
  • Timely communications with internal teams, investigators, review boards, and study subjects
  • Perform trial procedures as per delegation which can include the following but not limited to:
  • Prescreen study candidates by telephone and review exclusionary conditions or medications prior to scheduling screening appointment.
  • Obtain informed consent per SOP.
  • Administer delegated study questionnaires, as appropriate.
  • Collect and evaluate medical records.
  • Complete visit procedures and ensure proper specimen collection, processing, and shipment in accordance with protocol.
  • Train others and complete basic clinical procedures, such as blood draws, vital signs, ECGs, etc.
  • Review screening documentation and approves subjects for admission to study.
  • Review admission documentation and approves subject for randomization.
  • Provide ongoing assessment of the study subject/patient to identify Adverse Events.
  • Ensure that serious and unexpected adverse events are reported promptly to the Pl.
  • Review and evaluates all study data and comments to the clinical significance of any out-of-range results.
  • Perform physical examinations as part of screening evaluation and active study conduct.
  • Provide medical management of adverse events as appropriate.
  • Dispense study medication per protocol and/or IVRS systems. Educate patient on proper administration and importance of compliance.
  • Monitor patient progress on study medication.
  • Other duties as assigned.
The Expertise Required
  • Ability to check, perform, and document vitals as well as EKG (ECG)
  • Phlebotomy and expert IV skills
  • Excellent working knowledge of medical and research terminology
  • Excellent working knowledge of federal regulations, good clinical practices (GCP)
  • Ability to communicate and work effectively with a diverse team of professionals.
  • Strong organizational skills: Able to prioritize, support, and follow through on assignments with good understanding of medical terminology.
  • Communication Skills: Strong verbal and written communication skills as evidenced by positive interactions with coworkers, management, clients and vendors.
  • Communication Skills: Strong verbal and written communication skills as evidenced by positive interactions with coworkers, management, clients and vendors.
  • Team Collaboration Skills: Work effectively and collaboratively with other team members to accomplish mutual goals. Bring positive and supportive attitude to achieving these goals.
  • Strong computer skills with demonstrated abilities using clinical trials database, IVR systems, electronic data capture, MS word and excel.
  • Ability to balance tasks with competing priorities.
  • Critical thinker and problem solver.
  • Curiosity and passion to learn, innovative, and able to take thoughtful risks while communicating concerns and mitigations.
  • Good management and organizational skills, understanding of medical procedures.
  • Exceptional interpersonal skills, willingness to the ability to work independently.
  • Ability to lift a minimum of 50 pounds.
  • Command of professional and Business English (written and spoken).
  • You must have the authorization to work in the US for any employer.
  • You must not need visa sponsorship, either now or in the future.
  • You must live in the USA and be willing and able to travel with 24–36-hour notice
Certifications/Licenses, Education, and Experience:
  • At least Master's Level Science Degree. Nurse Practitioner or Physician Assistant with 5+ years of clinical experience.
  • Clinical practice experience desired with infusion skillset.
  • Currently licensed in good standing in one or more states.
  • A minimum of 1 year of relevant work experience as Sub-Investigator (preferred) in a Clinical Research setting.
  • Preferred at least one (1) year of experience as a Clinical Research Coordinator or willingness to learn.
How We Work Together
  • Location: Remote within the United States. This is an on-site mixed with remote tele-medicine work position.
  • Travel: Regional and nationwide travel requirements up to 100% dependent on project design and business need. Regularly planned travel will be required as part of the role.
  • Physical demands associated with this position Include: The ability to use keyboards and other computer equipment.

The expected salary range for this role is $130,000 - $165,000 USD per year for full time team members.

Benefits & Perks (US Full Time Employees)
  • Paid Time Off (PTO) and Company Paid Holidays
  • 100% Employer paid medical, dental, and vision insurance plan options
  • Health Savings Account and Flexible Spending Accounts
  • Bi-weekly HSA employer contribution
  • Company paid Short-Term Disability and Long-Term Disability
  • 401(k) Retirement Plan, with Company Match

Diversity & Inclusion

We work with and serve people from diverse cultures and communities around the world. We are stronger and better when we build a team representing the communities we support. We maintain an inclusive culture where people from a broad range of backgrounds feel valued and respected as they contribute to our mission.

We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to, and will not be discriminated against on the basis of, race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.

Care Access is unable to sponsor work visas at this time.

If you need an accommodation to apply for a role with Care Access, please reach out to: TalentAcquisition@careaccess.com

Mandatory Employer Disclosures:
Notice to Illinois applicants: Applicants are not obligated to disclose expunged juvenile records or adjudication, arrest, or conviction.
Notice to Connecticut applicants: Care Access may require applicants to submit to a urinalysis drug test in connection with an application for employment.
Notice to Arizona, Georgia, Indiana, and North Dakota applicants: Care Access complies with applicable laws prohibiting smoking in and around places of employment.
Notice to Massachusetts applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Notice to Rhode Island applicants: Care Access complies with Rhode Island law prohibiting smoking in enclosed areas within places of employment. Care Access is also subject to is subject to Chapters 29–38 of Title 28 of the Rhode Island General Laws.
Notice to Maryland applicants: UNDER MARYLAND LAW, AN EMPLOYER MAY NOT REQUIRE OR DEMAND, AS A CONDITION OF EMPLOYMENT, PROSPECTIVE EMPLOYMENT, OR CONTINUED EMPLOYMENT, THAT AN INDIVIDUAL SUBMIT TO OR TAKE A LIE DETECTOR OR SIMILAR TEST. AN EMPLOYER WHO VIOLATES THIS LAW IS GUILTY OF A MISDEMEANOR AND SUBJECT TO A FINE NOT EXCEEDING $100.