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Sub Investigator Jobs (NOW HIRING)

Flourish Research

Sub-Investigator

Walnut Creek, CA · On-site

$72 - $82/hr

We are actively hiring a Sub-Investigator to support our Walnut Creek site. Shift: Monday-Friday day shift (40 hours per week) Location: Onsite FLSA Classification: Exempt Compensation: $72.00-$82.00 ...

Flourish Research

Sub-Investigator

Walnut Creek, CA · On-site

$72 - $82/hr

We are actively hiring a Sub-Investigator to support our Walnut Creek site. Shift: Monday-Friday day shift (40 hours per week) Location: Onsite FLSA Classification: Exempt Compensation: $72.00-$82.00 ...

Medix

Sub-Investigator

Garden City, MI · On-site

$67.31 - $81.73/hr

Job Summary Our client is seeking a Sub-Investigator to play a critical role in the execution of clinical trials. The primary responsibilities include supporting the Principal Investigator in ...

Medix

Sub-Investigator

Austin, TX · On-site

$74.52 - $85.10/hr

Job Summary Our client is seeking a dedicated Sub-Investigator to join their team with an expertise in clinical trial assessments and psyciatric diagnostic. This role focuses on administering ...

Velocity Clinical Research, Inc.

Sub Investigator

Norfolk, NE · On-site

$45K - $46K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

Velocity Clinical Research, Inc.

Sub Investigator

Norfolk, NE · On-site

$45K - $46K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

Medix

Sub-Investigator

La Vergne, TN · On-site

$76.92 - $144.23/hr

Job Summary Our client is seeking a Sub-Investigator responsible for conducting study visits, including medical assessments and ensuring compliance with study protocols. The focus will be on ...

Care Access

Travel Sub-Investigator

Boston, MA

$50K - $51K/yr

How This Role Makes a Difference The Sub-Investigator will be responsible for travel mixed with remote tele-medicine work to support our clinical research studies.  Additionally, our Sub ...

Pinnacle Clinical Research

Sub-Investigator

San Antonio, TX · On-site

$40K - $40K/yr

Summary: The Clinical Research Nurse Practitioner/Physician Associate will be listed as a sub-investigator on all ongoing study protocols. She/He will be a key member of the team and will be ...

Care Access

Travel Sub-Investigator

$47K - $48K/yr

Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract - 6 months with the possibility to go perm We're seeking an ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract -6 months with the possibility to go perm Overview The Sub ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract -6 months with the possibility to go perm Overview The Sub ...

System One

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract - 6 months with the possibility to go perm We're seeking an ...

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How much do sub investigator jobs pay per year?

As of Aug 23, 2026, the average yearly pay for sub investigator in the United States is $75,325.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $98,500.00 per year, depending on experience, location, and employer.

What is a sub investigator?

A Sub Investigator (Sub-I) is a clinical research professional who assists the Principal Investigator (PI) in conducting clinical trials. They ensure that studies comply with regulatory requirements, oversee patient care, and manage data collection. Sub-Is may perform medical evaluations, review patient histories, and ensure study protocols are followed. Their role is essential in maintaining the integrity of a clinical trial while ensuring participant safety.

What are the typical responsibilities of a sub investigator during a clinical trial?

As a Sub Investigator, you will assist the Principal Investigator in overseeing the day-to-day conduct of clinical trials, which includes monitoring study participants, ensuring protocol adherence, and maintaining accurate study documentation. You may conduct physical exams, review laboratory results, and report adverse events while ensuring all regulatory and ethical guidelines are followed. Collaboration is frequent, both with study coordinators and other research staff, to maintain trial quality and participant safety. This hands-on involvement allows you to gain valuable experience in clinical research operations, often serving as a foundation for upward career mobility.

What are the key skills and qualifications needed to thrive as a sub investigator?

To thrive as a Sub Investigator, you need a background in clinical research, attention to detail, and knowledge of Good Clinical Practice (GCP) guidelines, often supported by a relevant healthcare or scientific degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification is beneficial. Strong organizational skills, teamwork, and clear written and verbal communication help set candidates apart. These capabilities are crucial for ensuring regulatory compliance, accurate study documentation, and effective coordination with principal investigators and research teams.

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Cities with the most Sub Investigator job openings:

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Sub Investigator jobs near you
Infographic showing various Sub Investigator job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 86% Full Time, 9% Part Time, 2% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $75,325 per year, or $36.2 per hour.

Sub-Investigator

Flourish Research

Walnut Creek, CA • On-site

$72 - $82/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 12 days ago

Job description

About Us:
Flourish Research is where clinical trials thrive. Flourish Research is one of the industry's most progressive and diversified clinical trial organizations, with strong capabilities across cardiology, metabolic disorders, renal, oncology, CNS, pulmonology, and vaccine research. At Flourish Research, we strive toward excellence. In clinical trials and healthcare, excellence means everyone deserves the best care, regardless of their race, color, gender identity, religion, ethnicity, physical abilities, age, sexual orientation, or veteran status. We embrace employees, customers, and patients from these underrepresented groups to help make this vision a reality. Flourish is committed to a safe work environment where all employees, customers, and patients are included, and treated with dignity and respect. The more diversity we have in our team, the more unique perspectives, and ideas we share, and the better prepared we are to serve our communities. WE SEE YOU. WE ARE YOU. WE EMBRACE YOU. WE CELEBRATE YOU!
Flourish Research is looking for motivated, talented, creative individuals who want to learn and grow in their careers while contributing to research that changes lives! We offer an excellent comprehensive benefits package, a supportive and collaborative work environment, and endless growth opportunities.
About the Job:
We are actively hiring a Sub-Investigator to support our Walnut Creek site.
Shift: Monday-Friday day shift (40 hours per week)
Location: Onsite
FLSA Classification: Exempt
Compensation: $72.00-$82.00 per hour
Requirements
Essential Job Function:
  • Represent Flourish Research in a professional and courteous manner (verbal, written, and in appearance) during all interactions with sponsors, physicians, physicians' office personnel, participants, Flourish Research employees, Flourish Research contract personnel, as well as any other person(s) when carrying out tasks and responsibilities.
  • Ensure the maintenance of confidentiality of participant information by team members as appropriate and as bound by Confidentiality Agreements with Flourish Research, between Flourish Research and sponsors/CROs, and between Flourish Research and other entities while abiding by HIPAA regulations.
  • Possess a thorough knowledge and understanding of the requirements of each study protocol including any amendment changes, as applicable.
  • Work closely under the Primary Investigator to manage the safety of study participants, assess inclusionary and exclusionary study criteria, monitor laboratory results, ensure appropriate follow up as necessary, and maintain adherence to study protocol and procedures.
  • Perform study-related procedures, injections, physical examinations, clinical interviews, clinical rating scales, psychological testing, and neurological assessments. Interpret laboratory results, facilitate participant care, and ensure appropriate follow up per protocol.
  • Maintain protocol compliance, including following schedule of assessments, implementing only protocol deviations or changes approved by the sponsor/CRO and IRB (except to eliminate immediate hazards to the participant).
  • Acquire thorough knowledge of the inclusion/exclusion criteria, procedures, scheduled visits, end point criteria, and investigational article use and share relevant information with the research team to include information in the current investigator's brochure, product insert, or other source information, as well as other information about the investigational product(s).
  • Assess participant compliance to investigational product. Evaluate adverse experiences and determine severity and relationship to the investigational product.
  • Ensure that medical care is provided to a participant for any adverse event(s) as needed.
  • Document and report all serious adverse events to the sponsor/CRO and IRB within 24 hours of the site's knowledge of the event.
  • Obtain signed and dated informed consent from the study participant or participant's legal representative prior to initiating any study-related procedures.
  • Inform the participant or legal representative about all aspects of the clinical trial.
  • Document that informed consent has been obtained from the participant or legal representative.
  • Always consider participant safety and welfare the priority.
  • Ensure the accuracy, completeness, legibility, and timeliness of source documentation and case report forms (CRFs) as applicable.
  • Review and sign data management queries and case report forms (CRFs) in a timely manner as applicable.
  • Document and explain premature unblinding of the investigational product(s) when necessary.
  • Evaluate results and documented findings in participants' medical records and Flourish Research CTMS, eDocs, Source.
  • Ensure validity and reliability when administering tests/scales/assessments by complying with established standards for administering psychometric testing and per sponsors' protocols.
  • Ascertain the reason for a participant's premature study withdrawal.

Physical Requirements and/or Environmental Factors:
  • Work is normally performed in a typical interior clinical/office work environment.
  • Participant Care

Minimum Requirements:
  • Medical (M.D.) degree, Doctor of Osteopathy (D.O.), Doctor of Nursing Practice (D.N.P.), Advanced Practice Registered Nurse (A.P.R.N.), Physician's Assistant (P.A.), Doctor of Psychology (PsyD).
  • A minimum of 2 years' experience in performing physicals, assessing, and treating patients. 1-3+ years' experience within the field of clinical research or biological research preferred; however, is not required.

Knowledge and Skills:
  • Possess strong supervision, interpersonal and communication skills.
  • Be able to make good, sound decisions under stress and time constraints.
  • Be able to make sound medical judgments on the health and safety of subjects during their participation in a clinical research study.
  • Maintain professional and technical knowledge by attending educational workshops in other activities to maintain continuing medical education requirements.
  • Review professional publications.
  • Possess exceptional organizational and planning skills and good documentation skills.
  • Have good conflict resolution skills and be committed to quality and honesty.
  • Possess in-depth knowledge of the clinical research process, including Good Clinical Practices.

Benefits
Health, dental, and vision insurance plans, 401(k) with a 100% employer match on the first 4% of employee contributions, tuition reimbursement, parental leave, employee referral program, employee assistance program, life insurance, disability insurance, and a generous PTO plan covering vacation, sick, personal days and 8 paid holidays.
Flourish Research is an equal employment opportunity employer. Employment decisions are based on merit and business needs, and not on race, color, sex, (including pregnancy and gender identity), citizenship status, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, genetic information, marital status, veteran status, political affiliation, or any other factor protected by law. Flourish Research complies with the law regarding reasonable accommodation for handicapped and disabled employees.

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