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Sub Investigator Jobs (NOW HIRING)

Johnson County Clin Trials

Sub-Investigator

Houston, TX · On-site

$52/hr

The purpose of the Sub-Investigator role is to ensure the safe, ethical, and effective medical oversight of volunteers participating in clinical research studies at Johnson County Clin-Trials. This ...

Johnson County Clintrials

Sub-Investigator

Houston, TX · On-site

Sub-Investigator (CRC) Purpose: The purpose of the Sub-Investigator role is to ensure the safe, ethical, and effective medical oversight of volunteers participating in clinical research studies at ...

DM Clinical Research

Sub-Investigator

Plymouth, MA

$50K - $51K/yr

Sub-Investigator (Nurse Practitioner) The Sub-Investigator is accountable and responsible for ensuring adherence to protocol requirements, protecting the rights and welfare of subjects, assuring the ...

Velocity Clinical Research, Inc.

Sub Investigator

Omaha, NE · On-site

$39K - $39K/yr

The Sub Investigator has responsibility for the clinical safety of the patients partaking in the clinical trial, collecting, and recording accurate clinical data while also ensuring that the well ...

Medix

Sub-Investigator

Chesterfield, MO · On-site

$62.50 - $72.12/hr

Job Summary Our client is seeking a Sub-Investigator to join their team at a laid-back site with a strong midwestern vibe. The position requires an NP, preferably someone with 3 years of practicing ...

System One Holdings, LLC

Sub-Investigator/PA

Kenmore, NY · On-site

$45 - $65/hr

Sub-Investigator/PA Location: Buffalo, New York Onsite Hours: 40 hours per week Compensation: $45.00 - $65.00 per hour Type: Contract -6 months with the possibility to go perm Overview The Sub ...

Pinnacle Clinical Research

Sub-Investigator

San Antonio, TX · On-site

$40K - $40K/yr

Summary: The Clinical Research Nurse Practitioner/Physician Associate will be listed as a sub-investigator on all ongoing study protocols. She/He will be a key member of the team and will be ...

Pinnacle Clinical Research

Sub Investigator

Bellaire, TX · On-site

$41K - $42K/yr

Summary: The Clinical Research Nurse Practitioner/Physician Associate will be listed as a sub-investigator on all ongoing study protocols. She/He will be a key member of the team and will be ...

Care Access

OR · On-site

$46K - $47K/yr

Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational ...

Care Access

Travel Sub-Investigator

$47K - $48K/yr

Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational ...

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How much do sub investigator jobs pay per year?

As of Jun 8, 2026, the average yearly pay for sub investigator in the United States is $75,325.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $98,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Sub Investigator position, and why are they important?

To thrive as a Sub Investigator, you need a background in clinical research, attention to detail, and knowledge of Good Clinical Practice (GCP) guidelines, often supported by a relevant healthcare or scientific degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification is beneficial. Strong organizational skills, teamwork, and clear written and verbal communication help set candidates apart. These capabilities are crucial for ensuring regulatory compliance, accurate study documentation, and effective coordination with principal investigators and research teams.

What are some typical responsibilities of a Sub Investigator during a clinical trial?

As a Sub Investigator, you will assist the Principal Investigator in overseeing the day-to-day conduct of clinical trials, which includes monitoring study participants, ensuring protocol adherence, and maintaining accurate study documentation. You may conduct physical exams, review laboratory results, and report adverse events while ensuring all regulatory and ethical guidelines are followed. Collaboration is frequent, both with study coordinators and other research staff, to maintain trial quality and participant safety. This hands-on involvement allows you to gain valuable experience in clinical research operations, often serving as a foundation for upward career mobility.

What is a Sub Investigator job?

A Sub Investigator (Sub-I) is a clinical research professional who assists the Principal Investigator (PI) in conducting clinical trials. They ensure that studies comply with regulatory requirements, oversee patient care, and manage data collection. Sub-Is may perform medical evaluations, review patient histories, and ensure study protocols are followed. Their role is essential in maintaining the integrity of a clinical trial while ensuring participant safety.

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What cities are hiring for Sub Investigator jobs? Cities with the most Sub Investigator job openings:
What are the most commonly searched types of Sub Investigator jobs? The most popular types of Sub Investigator jobs are:
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Sub Investigator jobs near you
Infographic showing various Sub Investigator job openings in the United States as of May 2026, with employment types broken down into 1% As Needed, 89% Full Time, 8% Part Time, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $75,325 per year, or $36.2 per hour.

Sub-Investigator

Johnson County Clin Trials

Houston, TX • On-site

$52/hr

Full-time

Posted 13 days ago

Job description

Job Type
Full-time
Description
Sub-Investigator (CRC)
Purpose:
The purpose of the Sub-Investigator role is to ensure the safe, ethical, and effective medical oversight of volunteers participating in clinical research studies at Johnson County Clin-Trials. This position supports the Principal Investigator by conducting medical evaluations, managing volunteer health throughout study participation, and ensuring adherence to study protocols and regulatory requirements. Through expert clinical assessment, collaborative teamwork, and strong communication, the Sub-Investigator helps maintain high-quality research standards, safeguards participant well-being, and contributes to the successful execution of clinical trials.
Position Summary:
The Sub-Investigator position is responsible for providing medical evaluation and care to volunteers enrolled in research studies conducted by Johnson County Clin-Trials. This is performed in conjunction with the Primary Investigator and other members of the multidisciplinary health care team. The Sub-Investigator screens new volunteers medically and manages them while actively participating in a study, and provides follow-up care, as needed. The Sub-Investigator screens new volunteers, provides medical management during study participation, and provides follow-up as, as needed. These activities may be performed in both in-patient and outpatient settings. This medical management includes assessment of acute and non-acute clinical problems and toxicities.
Customer service is critical in this role as the Sub-Investigator directly communicates with volunteers and other departments.
Key Responsibilities (Essential Functions):
  • Orders and interprets data obtained from diagnostic tests and laboratory studies
  • Orders appropriate medications and treatments for study volunteers
  • Provides volunteer and staff education
  • Participates in clinical rounds and conferences
  • Creates in depth documentation through written progress notes and dictations summaries
  • Maintains a high level of clinical competence in an area of specialty practice integrating the art and science of both nursing and medicine into practice
  • Independently assesses acute and non-acute clinical problems and toxicities
  • Performs and documents physical assessments and volunteer medical histories
  • Analyzes trends in patient conditions, and develops, documents, and implements a volunteer management plan in response to the data obtained
  • Serves as an associate investigator on protocols
  • Contributes to the implementation of specific protocols and the clinical management of volunteers on protocol
  • Collaborates with other disciplines in the obtaining and maintaining of informed consent/assent of volunteers on research protocols and prior to implementing invasive procedures
  • Interviews and screens volunteers for entry onto protocols
  • Monitors, documents, and communicates findings to Principal Investigators with recommendations for appropriate intervention
  • Uses advanced communication skills to problem solve complex situations and improve processes and services for volunteers and colleagues
  • Recognizes and reports adverse events/serious adverse events to study coordinators, Principal Investigators, FDA, and sponsors
  • Performs study procedures, as outlined in the protocols and within state and institutional scope of practice
  • Attends continuing education, research and training seminars as requested by management
  • Other duties as assigned

Education and Experience:
  • 5 years of previous clinical research experience working directly with clinicians/providers is required
  • License to practice as a Nurse Practitioner in the state of Kansas
  • Advanced understanding of regulations governing clinical research (CFR, GCP, HIPAA)
  • Advanced understanding of statutes and guidelines relevant to regulatory affairs in clinical research
  • Familiarity with or the ability to learn clinical trial management system software

Skills and Competencies:
  • Experience in customer service, telephone, and computers or equivalent training
  • Microsoft Office proficiency
  • Excellent written and verbal communication skills
  • Ability to work effectively with a team
  • Ability to manage small projects personally and work independently
  • Memory to retain information and know where to research answers
  • Strong time management skills
  • Effective organizational skills
  • Detail oriented with the ability to perform at a high level of accuracy
  • Demonstrates strong analytical, problem-solving skills
  • Self-motivated
  • Must be results oriented, multi-tasking, quick learner
  • Complex problem solving
  • Excellent interpersonal skills
  • Ability to establish and maintain effective working relationships with coworkers, managers and volunteers
  • In depth knowledge of clinical trials
  • In depth knowledge of Good Clinical Practices (GCP)
  • Ability to fully contribute to multidisciplinary teams including physicians, and administrative staff to assure that the goals and objectives of the program or project are

Physical Requirements:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of the job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.
  • Ability to sit, stand, walk, reach with hands and arms, and use hands along with fingers, to handle or feel
  • Prolonged periods of walking and standing are required
  • Ability to lift and/or move up to 50 pounds
  • Ability to bend and stoop
  • Ability to handle biological materials

Why JCCT?
JCCT has provided exceptional customer service to clients, volunteers, and vendors for the last 20 years. This team effort has resulted in our company getting recognized as one of the best clinical research sites in the United States.
We are actively growing through acquisition and organic growth and need high performing individuals to help support our continued success. Our clients come from all over the world to place a study at our research sites. We are proud of what we have accomplished and invite you to explore career opportunities with us. JCCT makes a promise to support, accept and respect you as an individual, in our family focused environment.
Our vision is to make a difference in our world to help improve the health and wellbeing of others through pharmaceutical research and the processes of drug development. Our impact is driven by genuine care, support and customer service provided to our employees, volunteers, and sponsors.
If you are looking for a positive work environment and the opportunity for personal growth and satisfaction, we encourage you to apply at JCCT. Qualified candidates will be contacted for interviews. Unleash your potential and apply today!
EEO
JCCT provides equal employment opportunities (EEO) to all employees and applicants. We value diversity at our company, and it is our policy to recruit, hire, and promote qualified individuals without regard to race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Salary Description
$52.00 per hour

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