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Sub Investigator Jobs (NOW HIRING)

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Principal Investigator

Baltimore, MD

$200K - $400K/yr

Train Sub-Investigators and study staff members on protocol and protocol specific procedures. Provide medical support to sub-investigators and study staff for protocol-related issues including ...

Care Access

Principal Investigator

Houston, TX

$200K - $400K/yr

Train Sub-Investigators and study staff members on protocol and protocol specific procedures. Provide medical support to sub-investigators and study staff for protocol-related issues including ...

Care Access

Principal Investigator

Mesa, AZ

$175K/yr

Train Sub-Investigators and study staff members on protocol and protocol specific procedures. Provide medical support to sub-investigators and study staff for protocol-related issues including ...

Gonzalez MD and Aswad MD Health

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Clinical Research PhD- sub - investigator / PI Track

Miami, FL · Remote

$500 - $1K/day

Clinical Research Sub-Investigator / PI-Track Research Lead (PhD) We are seeking a qualified PhD to join our clinical research site in a Sub-Investigator / research leadership role with potential ...

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$131K

How much do sub investigator jobs pay per year?

As of Jun 13, 2026, the average yearly pay for sub investigator in the United States is $75,325.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $98,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Sub Investigator position, and why are they important?

To thrive as a Sub Investigator, you need a background in clinical research, attention to detail, and knowledge of Good Clinical Practice (GCP) guidelines, often supported by a relevant healthcare or scientific degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and GCP certification is beneficial. Strong organizational skills, teamwork, and clear written and verbal communication help set candidates apart. These capabilities are crucial for ensuring regulatory compliance, accurate study documentation, and effective coordination with principal investigators and research teams.

What are some typical responsibilities of a Sub Investigator during a clinical trial?

As a Sub Investigator, you will assist the Principal Investigator in overseeing the day-to-day conduct of clinical trials, which includes monitoring study participants, ensuring protocol adherence, and maintaining accurate study documentation. You may conduct physical exams, review laboratory results, and report adverse events while ensuring all regulatory and ethical guidelines are followed. Collaboration is frequent, both with study coordinators and other research staff, to maintain trial quality and participant safety. This hands-on involvement allows you to gain valuable experience in clinical research operations, often serving as a foundation for upward career mobility.

What is a Sub Investigator job?

A Sub Investigator (Sub-I) is a clinical research professional who assists the Principal Investigator (PI) in conducting clinical trials. They ensure that studies comply with regulatory requirements, oversee patient care, and manage data collection. Sub-Is may perform medical evaluations, review patient histories, and ensure study protocols are followed. Their role is essential in maintaining the integrity of a clinical trial while ensuring participant safety.

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Sub Investigator jobs near you
Infographic showing various Sub Investigator job openings in the United States as of June 2026, with employment types broken down into 59% Full Time, 32% Part Time, 6% Contract, and 3% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $75,325 per year, or $36.2 per hour.

Clinical Research Sub-Investigator (NP/PA)

ObjectiveHealth

Springboro, OH • Hybrid

Other

Posted 7 days ago

Job description

Description

Clinical Research Sub-Investigator (NP/PA)

ObjectiveHealth is seeking a licensed Nurse Practitioner (NP) or Physician Assistant-Certified (PA-C) to serve as a Sub-Investigator at our Dayton, OH research site. This is a unique opportunity for an advanced practice provider in Internal Medicine, Family Medicine, or a related field to contribute to innovative clinical research while maintaining a flexible schedule.  This role is not benefit-eligible; however, it provides a flexible work arrangement and meaningful opportunities for professional growth and development. 


Schedule:

  • Part-time
  • Daytime hours
  • 2-3 days/week (flexible days)
  • 16-24 hours/week

ObjectiveHealth is a clinical research company transforming how research is conducted at the point of care. Using our proprietary technology, we aim to:

  • Increase patient access to research trials within our communities
  • Provide physicians with enhanced care options for current patients
  • Deliver superior clinical research enrollment metrics to Pharma sponsors

All with the ultimate goal of Improving Patient Outcomes at the Point of Care. We want you to join us in doing just that.


Key Responsibilities:

  • Serve as the Sub Investigator for assigned clinical trials, ensuring overall study oversight.
  • Oversee and enforce compliance with study protocols while prioritizing subject safety at all times.
  • Conduct and document physical examinations and medical assessments in accordance with research protocol requirements.
  • Provide continuous medical oversight throughout all phases of the clinical trial lifecycle.
  • Collaborate effectively with study coordinators, site staff, and other research team members to ensure smooth study execution.
  • Participate in sponsor meetings, site initiation visits, monitoring visits, and audits as needed.
  • Maintain strict compliance with GCP, ICH guidelines, FDA regulations, and internal SOPs.

Qualifications:

  • Licensed Nurse Practitioner (NP) or Physician Assistant-Certified (PA-C) with an active license in the state of Ohio.
  • Leadership experience in clinical or healthcare settings is preferred.
  • Ability to perform study-related clinical assessments and procedures under the guidance of the Principal Investigator.
  • Strong attention to detail and commitment to maintaining high ethical, clinical, and regulatory standards.
  • Excellent communication and interpersonal skills, with the ability to collaborate effectively in a multidisciplinary research environment.


Requirements

This job requires legal authorization to work in the US. We are not currently accepting work visas. ObjectiveHealth is an EEO Employer and an E-Verify participant

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