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Startup Program Manager Jobs in Colorado (NOW HIRING)

Foresight Diagnostics

Program Manager

Boulder, CO · On-site +1

Following our acquisition by Natera, we now combine the agility of a mission-driven startup with ... WHY THIS ROLE EXISTS The Program Manager will lead cross-functional programs supporting product ...

Foresight Diagnostics Inc.

Program Manager

Aurora, CO · On-site +1

Following our acquisition by Natera, we now combine the agility of a mission-driven startup with ... WHY THIS ROLE EXISTS The Program Manager will lead cross-functional programs supporting product ...

CesiumAstro

Program Manager

Westminster, CO · On-site

$113K - $136K/yr

If you enjoy working in a startup environment, and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

CesiumAstro

Program Manager

Westminster, CO

If you enjoy working in a startup environment, and managing multiple fast paced projects at once, we would like to hear from you.  In this position, you will be responsible for program performance ...

CesiumAstro

Program Manager

Westminster, CO

$113K - $136K/yr

If you enjoy working in a startup environment, and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

York Space Systems

Program Manager

Greenwood Village, CO · On-site

$130K - $210K/yr

Job Summary The Program Manager owns execution for a single mission or small constellation, leading ... Experience in high-growth startup environments. Key Benefits: * 100% employer-paid medical, dental ...

CesiumAstro

Senior Program Manager

Westminster, CO

$117K - $117K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you.  In this position, you will be responsible for program performance ...

CesiumAstro

Senior Program Manager

Westminster, CO · On-site

$184K - $225K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

CesiumAstro

Senior Program Manager

Westminster, CO

$184K - $225K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

CesiumAstro

Senior Program Manager

Westminster, CO · On-site

$183K - $225K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

CesiumAstro

Senior Program Manager

Westminster, CO

$117K - $117K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you.  In this position, you will be responsible for program performance ...

CesiumAstro

Senior Program Manager

Westminster, CO · On-site

$183K - $225K/yr

If you enjoy working in a startup environment and managing multiple fast paced projects at once, we would like to hear from you. In this position, you will be responsible for program performance and ...

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All JobsStartup Program JobsStartup Program Manager JobsStartup Program Manager Jobs in Colorado

Startup Program Manager information

See Colorado salary details

$40.5K

$113K

$165.1K

How much do startup program manager jobs pay per year?

As of Jun 10, 2026, the average yearly pay for startup program manager in Colorado is $112,997.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,600.00 and $139,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Startup Program Manager, and why are they important?

To thrive as a Startup Program Manager, you need expertise in project management, business development, and a deep understanding of the startup ecosystem, often supported by a degree in business or a related field. Familiarity with tools like CRM platforms, project management software (e.g., Asana, Trello), and metrics tracking systems is typical, and certifications such as PMP can be advantageous. Outstanding communication, adaptability, and relationship-building skills set top performers apart in this dynamic environment. These competencies are crucial for successfully guiding startups through growth phases, fostering innovation, and ensuring program objectives are met.

How does a Startup Program Manager typically collaborate with founders and cross-functional teams to drive program success?

A Startup Program Manager often acts as the central point of contact between startup founders, mentors, investors, and internal teams such as marketing, product, and operations. They facilitate communication, coordinate resources, and ensure that startups in the program receive the support they need to reach key milestones. This requires strong relationship-building skills and the ability to manage multiple projects simultaneously. Collaboration may involve organizing workshops, conducting regular check-ins, and leveraging internal expertise to help startups overcome challenges and scale effectively.

What is the difference between Startup Program Manager vs Startup Project Coordinator?

AspectStartup Program ManagerStartup Project Coordinator
ResponsibilitiesOversees multiple programs, strategic planning, stakeholder managementSupports project execution, schedules, task coordination
Required SkillsProgram management, leadership, communicationOrganization, communication, task management
CertificationsProject Management Professional (PMP), Agile certificationsBasic project management knowledge, certifications optional
Work EnvironmentFast-paced startup, cross-functional teamsTeam support, project-focused environment

The Startup Program Manager typically handles multiple programs, focusing on strategic oversight and stakeholder engagement, while the Startup Project Coordinator supports specific projects with task management and coordination. Both roles require strong communication skills, but the Program Manager's role is more strategic and leadership-oriented, whereas the Coordinator's role is more execution-focused.

What is a Startup Program Manager?

A Startup Program Manager is a professional responsible for designing, managing, and optimizing programs that support startup companies, such as accelerators, incubators, or corporate innovation initiatives. They work closely with entrepreneurs, investors, and mentors to provide resources, mentorship, and guidance to early-stage companies. Their role involves overseeing program logistics, selecting participants, organizing events, and tracking the progress of startups throughout the program. Startup Program Managers play a crucial role in fostering innovation and helping startups grow and succeed.
What are popular job titles related to Startup Program Manager jobs in Colorado? For Startup Program Manager jobs in Colorado, the most frequently searched job titles are:
What job categories do people searching Startup Program Manager jobs in Colorado look for? The top searched job categories for Startup Program Manager jobs in Colorado are:
What cities in Colorado are hiring for Startup Program Manager jobs? Cities in Colorado with the most Startup Program Manager job openings:
Startup Program Manager jobs near you
Infographic showing various Startup Program Manager job openings in Colorado as of June 2026, with employment types broken down into 40% Full Time, 47% Part Time, and 13% Contract. Highlights an 81% Physical, 2% Hybrid, and 17% Remote job distribution, with an average salary of $112,997 per year, or $54.3 per hour.
Program Manager

Program Manager

Foresight Diagnostics

Boulder, CO • On-site, Remote

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 20 days ago

Job description

Location Type: Remote (USA) with up to 25% travel
ABOUT FORESIGHT DIAGNOSTICS
Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer.
We sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It's an exciting moment to join us.
Headquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren't just values - they're how we work every day.
WHY THIS ROLE EXISTS
The Program Manager will lead cross-functional programs supporting product development initiatives at the Boulder, CO site. Projects and programs may include development, validation, and regulatory submission of diagnostic products; support of biopharma companion diagnostic (CDx) partnerships; and product sustainment and lifecycle management efforts. This role is responsible for driving execution across product development cross functional teams, including R&D, software, manufacturing, laboratory operations, quality, regulatory, clinical development, commercial, alliance management, and external partners, to ensure timely, compliant delivery of key milestones and contractual commitments.
The Program Manager will partner with functional leaders and stakeholders to translate product strategy into executable plans, manage cross-functional dependencies, and maintain alignment across internal and external stakeholders. This role requires strong program management fundamentals, experience and comfort operating in regulated environments, and the ability to coordinate complex, multi-disciplinary efforts simultaneously. The Program Manager will drive, communicate, and engage all project partners to enable accountability, problem solving, and on-time/within-budget delivery for simultaneous projects and programs. Success in this role requires onsite engagement (up to 25% travel) to facilitate rapid decision-making, build alignment, and resolve issues in a highly collaborative, fast-paced setting. This position reports to the Associate Director of Program Management.
WHAT YOU'LL DO
  • Drive end-to-end execution of product development programs, including planning, scheduling, resource coordination, and risk management across assay, software, and systems development, ensuring alignment with regulatory and business requirements
  • Support regulatory product development activities, ensuring alignment with regulated processes and quality systems, including design control processes (ISO 13485), software lifecycle standards (IEC 62304), change management, and quality system requirements (FDA, CAP/CLIA), including documentation and traceability of requirements and deliverables
  • Coordinate regulatory submission readiness, including support for Investigational Device Exemptions (IDEs), pre-submissions, and other global regulatory filings
  • Lead cross-functional alignment across R&D, software, regulatory, quality, and clinical teams to ensure clear requirements, priorities, and deliverables
  • Translate product strategy into actionable program roadmaps, including timelines, milestones, and interdependencies, ensuring alignment with organizational priorities and securing stakeholder buy-in
  • Extract and refine user needs and requirements from stakeholders and lead teams to focus on the most valuable deliverables
  • Partner with Alliance Management to manage external biopharma and CDx partnerships, coordinating joint program plans, deliverables, timelines, and communication across organizations
  • Adhere to formal governance processes to communicate program status, risks, and trade-offs; escalate issues as needed; and present data-driven recommendations and business proposals to senior leadership to enable timely, informed decision-making
  • Identify, track and manage program risks and dependencies, proactively identifying mitigation strategies and driving issue resolution
  • Drive cross-functional accountability, influencing without direct authority to ensure alignment, ownership, and timely execution
  • Support continuous improvement of product development processes, tools, and cross-functional ways of working
  • Cultivate, build and maintain positive and collaborative relationships with cross-functional teams

WHAT YOU'LL BRING
  • 3-5+ years of experience in program management, or equivalent combination of project management and relevant functional experience in biotechnology, diagnostics, clinical laboratory, or life sciences
  • Experience supporting product development in regulated environments (IVD, medical device, or similar)
  • Background in NGS diagnostics, including assay and software components (MRD experience preferred)
  • Strong familiarity with design controls (ISO 13485) and software lifecycle processes (IEC 62304)
  • Experience supporting regulatory submissions (e.g., IDE, 510(k), PMA, or equivalent) preferred
  • Exposure to clinical trial operations and execution (preferred)
  • Experience working with external partners, such as biopharma or CDx collaborations (preferred)
  • PMP or equivalent certification preferred
  • Ability to influence senior stakeholders and drive alignment in matrixed organizations
  • Strong organizational and program management skills, with the ability to manage multiple concurrent initiatives
  • Analytical mindset with strong attention to detail and ability to identify risks and dependencies
  • Excellent executive communication skills, with the ability to tailor messaging across technical and non-technical audiences
  • Proficiency with program management and collaboration tools (e.g., Smartsheet, Jira, Office Timeline, etc.)
  • Situational awareness, coupled with facilitation, problem solving, and conflict resolution skills to drive cross-functional decision-making
  • This position may be required to work across time zones as needed to support project schedules

COMPENSATION, BENEFITS & EQUAL OPPORTUNITY
This role offers a competitive annual base compensation of $120,000 - $140,000 commensurate with experience, and a comprehensive benefits package including:
  • Medical, dental, and vision
  • Flexible PTO and paid holidays
  • Parental leave
  • 401(k) with company match

You will be working on interesting problems with extremely high impact. We promote the professional development of our teams and encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Ready to make an impact in cancer diagnostics?
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