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Sr Clinical Research Associate Jobs in Spring, TX

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Clinical Research Associate II

Houston, TX · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

410 ICR United States USA

CRA II

Houston, TX · Remote

$91K - $114K/yr

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a CRA II at ICON, you will play a pivotal role in designing and analyzing clinical trials ...

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CRA II and Senior CRA

Houston, TX · Remote

$91K - $114K/yr

We are currently seeking a Clinical Research Associate (Level II or Senior) to join our diverse and dynamic team. As a CRA II/Senior CRA at ICON, you will play a pivotal role in designing and ...

Horizon Clinical Research

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Clinical Research Assistant

Cypress, TX · On-site

$37K - $47K/yr

We are seeking an experienced and detail oriented Clinical Research Assistant (CRA) for our Cypress, TX and Houston, TX office. This is a full time position. The CRA will work under the supervision ...

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Senior CRA

Houston, TX · On-site

Senior CRA Phase I Oncology TX ICON is a global healthcare intelligence and clinical research ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

410 ICR United States USA

Senior CRA

Houston, TX · On-site

Senior CRA Phase I Oncology TX ICON is a global healthcare intelligence and clinical research ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

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Senior CRA

Houston, TX · On-site

Senior CRA - Central/West ICON is a global healthcare intelligence and clinical research ... Extensive experience as a Clinical Research Associate, with a strong understanding of clinical ...

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All JobsSr Clinical Research Associate JobsSr Clinical Research Associate Jobs in Spring, TX

Sr Clinical Research Associate information

See Spring, TX salary details

$32K

$83.9K

$127.7K

How much do sr clinical research associate jobs pay per year?

As of Aug 26, 2026, the average yearly pay for sr clinical research associate in Spring, TX is $83,929.00, according to ZipRecruiter salary data. Most workers in this role earn between $55,600.00 and $113,900.00 per year, depending on experience, location, and employer.

What is a Sr Clinical Research Associate?

A Sr Clinical Research Associate (Senior CRA) is an experienced professional responsible for overseeing clinical trials to ensure they comply with regulatory requirements, protocols, and Good Clinical Practice (GCP) guidelines. They monitor study sites, review data, ensure participant safety, and act as a liaison between the sponsor and clinical sites. Senior CRAs often mentor junior staff, manage multiple studies, and contribute to improving clinical trial processes. Their role is vital in bringing new medical treatments and devices from research to market.

What are the key skills and qualifications needed to thrive as a Sr Clinical Research Associate?

To thrive as a Sr Clinical Research Associate, you need a robust background in clinical research, regulatory compliance, and study monitoring, usually supported by a bachelor's degree in life sciences and significant industry experience. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and certifications such as ACRP or SOCRA are highly valued. Outstanding attention to detail, strong organizational skills, and effective communication enable successful oversight of trial sites and collaboration with study teams. These skills are vital for ensuring the integrity, safety, and compliance of clinical trials, directly impacting study outcomes and regulatory approval.

What are some common challenges faced by a Sr Clinical Research Associate when monitoring multiple clinical trial sites?

As a Sr Clinical Research Associate (CRA), juggling multiple trial sites can be challenging due to varying site compliance levels, differing investigator engagement, and diverse patient populations. You may encounter issues such as inconsistent data entry, protocol deviations, and varying levels of site staff training. Effective time management, strong communication skills, and a proactive approach to problem-solving are essential to ensure all sites adhere to protocols and timelines. Additionally, frequent travel and adapting to each site's workflow can add complexity, but these challenges also provide valuable opportunities for professional growth.

What is the difference between Sr Clinical Research Associate vs Clinical Research Associate?

AspectSr Clinical Research AssociateClinical Research Associate
Required credentialsBachelor's degree, experience, often certifications like CCRP or RACBachelor's degree, entry-level or less experience, certifications optional
Work environmentPharmaceutical companies, CROs, clinical trial sitesSimilar settings, often entry-level roles in clinical trials
Employer and industry usageUsed in pharmaceutical and biotech industries, more senior rolesCommon in clinical research, entry to mid-level roles
Search and comparison intentOften searched for career progression or senior rolesOften searched for entry-level positions or understanding roles

The main difference between a Sr Clinical Research Associate and a Clinical Research Associate lies in experience, responsibilities, and qualifications. The senior role typically requires more experience, certifications, and involves overseeing complex trials, while the CRA is often an entry-level or mid-level position focused on supporting clinical trial activities.

What are popular job titles related to Sr Clinical Research Associate jobs in Spring, TX?

For Sr Clinical Research Associate jobs in Spring, TX, the most frequently searched job titles are:

What job categories do people searching Sr Clinical Research Associate jobs in Spring, TX look for?

The top searched job categories for Sr Clinical Research Associate jobs in Spring, TX are:

What cities near Spring, TX are hiring for Sr Clinical Research Associate jobs?

Cities near Spring, TX with the most Sr Clinical Research Associate job openings:

Sr Clinical Research Associate jobs near you
Infographic showing various Sr Clinical Research Associate job openings in Spring, TX as of August 2026, with employment types broken down into 2% As Needed, 76% Full Time, 15% Part Time, and 7% Contract. Highlights an 85% Physical, 1% Hybrid, and 14% Remote job distribution, with an average salary of $83,929 per year, or $40.4 per hour.

Clinical Research Associate II

Houston, TX • Remote

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See more jobs at Icon plcexternal

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 5 days ago

Job description

Senior CRA / CRA II - United States - Home Based

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


As a Senior CRA at ICON Plc, you will oversee and manage clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards.

What You Will Do:

You will lead on clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement.
Key responsibilities include:

  • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.
  • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.
  • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.
  • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.
  • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Your Profile:

You will have a strong foundation in clinical trial monitoring, with the experience to work independently and guide others.
Required qualifications and experience:

  • Bachelor's degree in a relevant scientific discipline or healthcare-related field
  • Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.
  • Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.
  • Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.
  • Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.
  • Willingness to travel as required (approximately 60%)

    #LI-LB1 #LI-REMOTE


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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