Senior Clinical Research Associate Jobs in Spring, TX

JoinImmaticsandshape thefuture ofcancerimmunotherapy; one patient at atime!

Immaticsis committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting ofPRAME, a target expressed in more than 50 cancers. Ourcutting-edgescience and robust clinical pipeline form the broadestPRAMEfranchise with the mostPRAMEindications and modalities, spanning TCR T-cell therapies and TCRbispecifics.

Why Join Us?

• Innovative Environment:Helptopioneeradvancementsin cancer immunotherapy.

• Collaborative Culture:Be part ofa diverse team dedicated to your professionalgrowth.

• Global Impact:Contributeto therapies thatmakealasting impactonpatientsglobally.

Role Overview:

We are seeking a Senior Clinical Research Associate (CRA) to support our Clinical Operations team. The Senior CRA willbe responsible foroverseeing clinical trial site management and monitoring activities to ensure compliance with ICH-GCP, regulatory requirements, and company SOPs. In this role, you will partner closely with clinical sites and cross-functional teams to support high-quality study execution, patient recruitment, and operational excellence across clinical trials.

Reports to:Associate Director, Team Lead Site Operations

Location:FullyRemote

Salary Range:$120,000 to $135,000

Basic Qualifications:

• Bachelor's degree in life sciences, nursing, or a related field

• 4+ years of on-site monitoring experience within the pharmaceutical or biotechnology industry, including all clinical monitoring visit types

• Strong knowledge of ICH-GCP, FDA, EMA, and applicable clinical trial regulations

• Demonstrated experience managing clinical trial sites,monitoringactivities, and clinical trial documentation

• Proficiencywith clinical trial systems and tools (e.g., CTMS, eTMF, Microsoft Office)

PreferredQualifications:

• Experience in oncology clinical trials or related therapeutic areas

• Advanced presentation, organizational, and stakeholder management skills

• Experience mentoring or training junior CRAs and supporting cross-functional clinical operations activities

• Demonstrated ability to drive quality, efficiency, and continuous improvement initiatives in clinical operations

• Strong understanding of clinical trial recruitment strategies, data capture, and site engagement best practices

• Experience contributing to global harmonization, process optimization, or operational innovation initiatives

In thisrole youwill:

• Conduct all clinical monitoring activities, including site qualification, initiation, routine monitoring, and close-out visits

• Support site feasibility, siteselection, and ongoing site management activities throughout the clinical trial lifecycle

• Review clinical trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectives

• Maintainaccurateandtimelymonitoring documentation, including trip reports and trial master file records

• Collaborate with vendors, clinical sites, and cross-functional teams to support study execution and operational compliance

• Participate in investigator meetings, clinical trial documentation development, and study team meetings

• Mentor junior CRA team members and contribute to continuous improvement of clinical operations processes and procedures

Travel required:Willingness to travel up to 75%. Valid Driver's License preferable.

Qualified candidates willparticipatein a structured interview process, which includes:

• An initialrecruiter phone screen (conducted via video)

• A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)

• A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TX

What do we offer?

AtImmatics, we believe in investing in our team's health,safetyand well-being.Here'swhat you can expectif youjoinImmatics

Comprehensive Benefits:

• Competitive rates forHealth, Dental, and Vision Insurance

• 4 weeks ofvacation,granted up front each year and prorated for firstand lastyear ofemployment.

• 12 company paid holidays

• 7daysof sick time

• 100%employer-paidlifeinsuranceup toat 1x annual salary, up to one hundred thousand dollars

• 100%employer-paidshort- andlong-Termdisabilitycoverage

• 401(k) withimmediateeligibilityandcompany match. The company will match100% of your contributions upto3% of yourbase salaryfor the first two yearsof employment, 4% foryears 2-3 of employment, and up to5%of your salaryfrom the fourth year onward of continued employment.

• Partiallypaidparentalleavefor eligible employees.

• Additionalvoluntary employee-paidbenefits and services,includingaccident,hospitalindemnity, andcriticalillnessinsurance, as well as identitytheftprotection andpetinsurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexualorientation, gender identity or expression, national origin, ancestry, age, marital status, disability, geneticinformation, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants withsincerely heldreligious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us atRecruitingUS@immatics.com.

Work Authorization

Applicants mustbe authorized towork in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, referencechecksand pre-employment drug screening, wherepermittedby applicable law. For certain roles,additionalscreenings such as a credit check or motor vehicle record review may berequired, where job-related and consistent with business necessity.