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Single Molecule Microscopy Jobs (NOW HIRING)

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Single Molecule Microscopy information

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$37K

$106K

$142.5K

How much do single molecule microscopy jobs pay per year?

As of Jul 3, 2026, the average yearly pay for single molecule microscopy in the United States is $106,012.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,000.00 and $104,000.00 per year, depending on experience, location, and employer.

What is single molecule microscopy?

Single molecule microscopy is an advanced imaging technique that allows scientists to observe and analyze individual molecules in real time, often within living cells. Unlike traditional microscopy, which looks at the collective behavior of many molecules, this method provides detailed insights into molecular interactions, dynamics, and functions at the single-molecule level. It is widely used in biophysics, chemistry, and cell biology to study processes such as protein folding, enzyme activity, and molecular transport. This technique requires highly sensitive equipment and specialized fluorescent labeling to detect and track single molecules with great precision.

What are the key skills and qualifications needed to thrive as a Single Molecule Microscopy Specialist, and why are they important?

To thrive in Single Molecule Microscopy, you need a strong background in physics, chemistry, or biology, typically with an advanced degree and experience in microscopy techniques. Familiarity with advanced fluorescence microscopy systems, data analysis software (such as ImageJ or MATLAB), and often certifications in laboratory safety are important. Attention to detail, problem-solving abilities, and effective communication help in troubleshooting experiments and collaborating with multidisciplinary teams. These skills are essential for generating accurate data, driving scientific discovery, and ensuring the reliability of experimental results.

What is the difference between Single Molecule Microscopy vs Fluorescence Microscopist?

AspectSingle Molecule MicroscopyFluorescence Microscopist
Required CredentialsAdvanced microscopy training, possibly PhD in biology or physicsSimilar; microscopy experience, often with a background in biology or chemistry
Work EnvironmentResearch labs, academic institutions, biotech companiesResearch labs, hospitals, biotech firms
Industry UsageSpecialized research in molecular biology, biophysicsBroad applications in cell biology, medical research

Single Molecule Microscopy and Fluorescence Microscopist roles share similar credentials and work environments, but Single Molecule Microscopy focuses on observing individual molecules, requiring specialized techniques. Fluorescence Microscopists often work with broader fluorescence imaging, making the roles distinct yet related in microscopy expertise.

What are some common challenges faced by single molecule microscopy researchers, and how can they be addressed?

Single molecule microscopy researchers often encounter challenges such as minimizing background noise, achieving high-resolution imaging, and ensuring sample stability during prolonged observations. Addressing these issues typically involves optimizing sample preparation protocols, using advanced imaging techniques like Total Internal Reflection Fluorescence (TIRF) microscopy, and implementing robust data analysis tools. Collaborating closely with physicists, chemists, and bioinformaticians can also help troubleshoot technical hurdles and improve experimental outcomes.
More about Single Molecule Microscopy jobs
What cities are hiring for Single Molecule Microscopy jobs? Cities with the most Single Molecule Microscopy job openings:
What states have the most Single Molecule Microscopy jobs? States with the most job openings for Single Molecule Microscopy jobs include:
What job categories do people searching Single Molecule Microscopy jobs look for? The top searched job categories for Single Molecule Microscopy jobs are:
Infographic showing various Single Molecule Microscopy job openings in the United States as of June 2026, with employment types broken down into 12% Locum Tenens, 17% Full Time, 5% Part Time, 10% Temporary, and 56% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $106,012 per year, or $51 per hour.
Postdoctoral Fellow

$60K/yr

Full-time

Posted 29 days ago


University Of Texas at Austin rating

8.1

Company rating: 8.1 out of 10

Based on 62 frontline employees who took The Breakroom Quiz

134th of 544 rated colleges and universities


Job description

Job Posting Title:
Postdoctoral Fellow
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Hiring Department:
Department of Neuroscience
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Position Open To:
All Applicants
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Weekly Scheduled Hours:
40
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FLSA Status:
Exempt from FLSA
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Earliest Start Date:
Jul 01, 2026
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Position Duration:
Expected to Continue Until Jun 30, 2027
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Location:
AUSTIN, TX
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Job Details:
General Notes
Positions are available for full-time Postdoctoral Fellows in the laboratory of Dr. Amy Lee, PhD in the Department of Neuroscience (https://neuroscience.utexas.edu) at The University of Texas at Austin.
Lee Lab: https://www.cachannel.net
Postdoctoral Fellow positions are for one year, and are renewable based upon availability of funding, work performance, and progress toward research goals.
We are broadly interested in Ca2+ signaling mechanisms underlying the development, function, and repair of the nervous system. Our current areas of research include studies of voltage-gated Ca2+ channels in the retina with a focus on the development and function of photoreceptor synapses, as well as how dysregulation of Ca2+ channels cause inherited retinal disorders. We are also studying the roles of calmodulin-like Ca2+ sensors in somatosensory functions and axonal outgrowth in dorsal root ganglion neurons. A new direction of the lab is to utilize fluorescence techniques to study the biophysical properties of Ca2+ channels at the single molecule level. We utilize techniques including patch clamp electrophysiology, confocal and two-photon imaging, molecular biology and biochemistry, and behavioral assays.
Purpose
To provide research support in the lab of Dr. Amy Lee for the Department of Neuroscience.
Responsibilities
  • Designing and executing research experiments that may involve any of the following: animal tissue dissections, surgery, and histology; molecular biology; biochemistry; cell culture; optical imaging; various forms of microscopy; behavioral assays; electrophysiology
  • Write manuscripts, grants, and other scientific documents
  • Mentor other lab personnel and collaborate on projects
  • Career development activities including participating in journal clubs, seminars, scientific conferences

Required Qualifications
  • PhD in neuroscience or related field received within the last three years
  • Experience in immunohistochemistry, various forms of microscopy (e.g., confocal and electron microscopy) molecular biology, and/or biochemistry

Preferred Qualifications
  • Knowledge of retinal or somatosensory neurobiology and associated techniques
  • First-author on at least one peer-reviewed publication

Salary Range
$60,782+ depending on qualifications
Working Conditions
  • May work around chemical fumes
  • May work around standard office conditions
  • May work around biohazards
  • May work around chemicals
  • Repetitive use of a keyboard at a workstation

Required Materials
  • Resume/CV
  • 3 work references with their contact information; at least one reference should be from a supervisor
  • Letter of interest

Important for applicants who are NOT current university employees or contingent workers: You will be prompted to submit your resume the first time you apply, then you will be provided an option to upload a new Resume for subsequent applications. Any additional Required Materials (letter of interest, references, etc.) will be uploaded in the Application Questions section; you will be able to multi-select additional files. Before submitting your online job application, ensure that ALL Required Materials have been uploaded. Once your job application has been submitted, you cannot make changes.
Important for Current university employees and contingent workers: As a current university employee or contingent worker, you MUST apply within Workday by searching for Find UT Jobs. If you are a current University employee, log-in to Workday, navigate to your Worker Profile, click the Career link in the left hand navigation menu and then update the sections in your Professional Profile before you apply. This information will be pulled in to your application. The application is one page and you will be prompted to upload your resume. In addition, you must respond to the application questions presented to upload any additional Required Materials (letter of interest, references, etc.) that were noted above.
Employment Eligibility:
Please make sure you meet all the required qualifications and you can perform all of the essential functions with or without a reasonable accommodation.
Retirement Plan Eligibility:
The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length. This position has the option to elect the Optional Retirement Program (ORP) instead of TRS, subject to the position being 40 hours per week and at least 135 days in length.
Background Checks:
A criminal history background check will be required for finalist(s) under consideration for this position.
Equal Opportunity Employer:
The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.
Pay Transparency:
The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information.
Employment Eligibility Verification:
If hired, you will be required to complete the federal Employment Eligibility Verification I-9 form. You will be required to present acceptable and original documents to prove your identity and authorization to work in the United States. Documents need to be presented no later than the third day of employment. Failure to do so will result in loss of employment at the university.
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E-Verify:
The University of Texas at Austin use E-Verify to check the work authorization of all new hires effective May 2015. The university's company ID number for purposes of E-Verify is 854197. For more information about E-Verify, please see the following:
  • E-Verify Poster (English and Spanish) [PDF]
  • Right to Work Poster (English) [PDF]
  • Right to Work Poster (Spanish) [PDF]

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Compliance:
Employees may be required to report violations of law under Title IX and the Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act (Clery Act). If this position is identified a Campus Security Authority (Clery Act), you will be notified and provided resources for reporting. Responsible employees under Title IX are defined and outlined in HOP-3031.
The Clery Act requires all prospective employees be notified of the availability of the Annual Security and Fire Safety report. You may access the most recent report here or obtain a copy at University Compliance Services, 1616 Guadalupe Street, UTA 2.206, Austin, Texas 78701.

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