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Single Molecule Microscopy Jobs (NOW HIRING)

Research Assistant

Nashville, TN · On-site

$18.50 - $25.50/hr

Recent faculty recruits are studying cell migration using super-resolution microscopy, single molecule analysis of microtubule dynamics, systems biology of intestinal epithelia, stem cell biology ...

The position requires a PhD in Chemistry (or an equivalent doctorate in an appropriate field) with a focus on cryogenic electron microscopy (Cryo-EM) and/or single molecule optical tweezers ...

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Single Molecule Microscopy information

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$37K

$106K

$142.5K

How much do single molecule microscopy jobs pay per year?

As of Jul 23, 2026, the average yearly pay for single molecule microscopy in the United States is $106,012.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,000.00 and $104,000.00 per year, depending on experience, location, and employer.

What is single molecule microscopy?

Single molecule microscopy is an advanced imaging technique that allows scientists to observe and analyze individual molecules in real time, often within living cells. Unlike traditional microscopy, which looks at the collective behavior of many molecules, this method provides detailed insights into molecular interactions, dynamics, and functions at the single-molecule level. It is widely used in biophysics, chemistry, and cell biology to study processes such as protein folding, enzyme activity, and molecular transport. This technique requires highly sensitive equipment and specialized fluorescent labeling to detect and track single molecules with great precision.

What are the key skills and qualifications needed to thrive as a Single Molecule Microscopy Specialist, and why are they important?

To thrive in Single Molecule Microscopy, you need a strong background in physics, chemistry, or biology, typically with an advanced degree and experience in microscopy techniques. Familiarity with advanced fluorescence microscopy systems, data analysis software (such as ImageJ or MATLAB), and often certifications in laboratory safety are important. Attention to detail, problem-solving abilities, and effective communication help in troubleshooting experiments and collaborating with multidisciplinary teams. These skills are essential for generating accurate data, driving scientific discovery, and ensuring the reliability of experimental results.

What is the difference between Single Molecule Microscopy vs Fluorescence Microscopist?

AspectSingle Molecule MicroscopyFluorescence Microscopist
Required CredentialsAdvanced microscopy training, possibly PhD in biology or physicsSimilar; microscopy experience, often with a background in biology or chemistry
Work EnvironmentResearch labs, academic institutions, biotech companiesResearch labs, hospitals, biotech firms
Industry UsageSpecialized research in molecular biology, biophysicsBroad applications in cell biology, medical research

Single Molecule Microscopy and Fluorescence Microscopist roles share similar credentials and work environments, but Single Molecule Microscopy focuses on observing individual molecules, requiring specialized techniques. Fluorescence Microscopists often work with broader fluorescence imaging, making the roles distinct yet related in microscopy expertise.

What are some common challenges faced by single molecule microscopy researchers, and how can they be addressed?

Single molecule microscopy researchers often encounter challenges such as minimizing background noise, achieving high-resolution imaging, and ensuring sample stability during prolonged observations. Addressing these issues typically involves optimizing sample preparation protocols, using advanced imaging techniques like Total Internal Reflection Fluorescence (TIRF) microscopy, and implementing robust data analysis tools. Collaborating closely with physicists, chemists, and bioinformaticians can also help troubleshoot technical hurdles and improve experimental outcomes.
More about Single Molecule Microscopy jobs
What cities are hiring for Single Molecule Microscopy jobs? Cities with the most Single Molecule Microscopy job openings:
What states have the most Single Molecule Microscopy jobs? States with the most job openings for Single Molecule Microscopy jobs include:
What job categories do people searching Single Molecule Microscopy jobs look for? The top searched job categories for Single Molecule Microscopy jobs are:
Infographic showing various Single Molecule Microscopy job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $106,012 per year, or $51 per hour.
Post Doctoral Fellow - Biochemistry & Molecular Medicine

Post Doctoral Fellow - Biochemistry & Molecular Medicine

West Virginia University

Morgantown, WV • On-site

$50K - $68K/yr

Other

Medical, Retirement, PTO

This job post has expired 1 day ago. Applications are no longer accepted.


West Virginia University rating

6.9

Company rating: 6.9 out of 10

Based on 61 frontline employees who took The Breakroom Quiz

416th of 560 rated colleges and universities


Job description

Description

The Department of Biochemistry & Molecular Medicine at West Virginia University is currently accepting applications for a Post Doctoral Fellow.

About the Opportunity

We are seeking a postdoctoral researcher to join Dr. Rong Liu's lab, in the Department of Biochemistry and Molecular Medicine. This position focuses on investigating the roles and mechanisms of molecular motor proteins in human sensory processes. It offers an exciting opportunity to utilize cutting-edge single-molecule techniques and high-resolution microscopy to understand the biophysics of sensory motors, their impact on cytoskeletal dynamics, and how defects in these motor proteins lead to human sensory diseases such as vision and hearing loss. The research will involve a multidisciplinary approach integrating modern recombinant protein expression, quantitative imaging, and iPSC-derived sensory neurons, with the goal of identifying new therapeutic targets for motor-related vision and hearing diseases.

The successful candidate will conduct independent research, collaborate within the team and with other scientists in the field, and receive dedicated mentorship to support their transition to the next stage of their scientific career. The salary for this position is competitive and commensurate with experience.

We strongly believe in work-life balance and keeping time for things we love outside our work. WVU offers generous benefits, including:
* 37.5-hour work week
* 13 paid holidays (staff holiday calendar)
* 24 annual leave (vacation) days per year (employee leave)
* 18 sick days per year (for when you're ill, for when you need time to care for sick family, for your own, or your family's, regularly scheduled medical appointments. Who is family for the purpose of this leave? A lot of people in your life including immediate relatives and in-laws as well as others considered to be members of your household living under the same roof)
* WVU offers a range of health insurance and other benefits
* 401(a) retirement savings with 6% employee contribution match, eligibility to continue health insurance, and other retiree perks. Looking for more retirement benefits information? Check out retirement health insurance benefits, retirement income, and FAQ's.
* Wellness programs
What You'll Do

  • Conducting experimental research to characterize motor proteins in a reduced reconstituted system and in live cellular environments.
  • Collaborating with team members to interpret data, generate hypotheses, and design follow-up experiments.
  • Summarizing research findings and drafting manuscripts for publication.
  • Presenting research findings at conferences and seminars.
  • Mentoring students and junior trainees.
Qualifications
  • PhD degree in life sciences or related field.
  • A minimum of one (1) first-author peer-reviewed academic paper(s) are required.
  • Research experience in working with purified proteins and modern fluorescent microscopy is highly desirable.
  • All qualifications must be met by the time of employment.
  • The successful candidate may be permitted to begin employment prior to degree confirmation with a letter certifying the trainee has completed all the requirements from their university.

Knowledge, Skills and Abilities

  • Strong background in molecular biology, protein biochemistry, iPSCs, or cellular mechanisms in vision and hearing processes.
  • Experiences with microscopy and high-throughput image quantification and data analysis.
  • Ability to work both independently and collaboratively in a multidisciplinary research environment.
  • Excellent communication skills and a track record of scientific productivity (publications, conference presentations).
About WVU

West Virginia University is a place of purpose and community. We take pride in our profound impact on the state of West Virginia and are committed to the personal and professional growth of our employees.

From the groundbreaking R1 research at our flagship campus in Morgantown to the career-oriented programs at WVU Potomac State in Keyser, and the technology-intensive programs at WVU Tech in Beckley, the contributions of WVU employees resonate across the state, touching lives and shaping futures.

At WVU, you will discover a supportive community that champions work-life balance and fosters a collaborative atmosphere. Our core values - service, curiosity, respect, accountability and appreciation - unite us as Mountaineers.

Join us at West Virginia University, where your work will make a lasting impact. To learn more about WVU, visit wvu.edu.

West Virginia University is an Equal Opportunity Employer. We invite all qualified applicants regardless of race, color, religion, sex, national origin, age, disability, genetic information, or Veteran status.

Job Posting: Jul 13, 2026
Posting Classification: FE/AP
Exemption Status: Exempt
Benefits Eligible: Yes
Schedule: Full-time

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