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Single Molecule Microscopy Jobs in Alabama (NOW HIRING)

Single Molecule Microscopy information

What is single molecule microscopy?

Single molecule microscopy is an advanced imaging technique that allows scientists to observe and analyze individual molecules in real time, often within living cells. Unlike traditional microscopy, which looks at the collective behavior of many molecules, this method provides detailed insights into molecular interactions, dynamics, and functions at the single-molecule level. It is widely used in biophysics, chemistry, and cell biology to study processes such as protein folding, enzyme activity, and molecular transport. This technique requires highly sensitive equipment and specialized fluorescent labeling to detect and track single molecules with great precision.

What are some common challenges faced by single molecule microscopy researchers, and how can they be addressed?

Single molecule microscopy researchers often encounter challenges such as minimizing background noise, achieving high-resolution imaging, and ensuring sample stability during prolonged observations. Addressing these issues typically involves optimizing sample preparation protocols, using advanced imaging techniques like Total Internal Reflection Fluorescence (TIRF) microscopy, and implementing robust data analysis tools. Collaborating closely with physicists, chemists, and bioinformaticians can also help troubleshoot technical hurdles and improve experimental outcomes.

What are the key skills and qualifications needed to thrive as a single molecule microscopy specialist, and why are they important?

To thrive in Single Molecule Microscopy, you need a strong background in physics, chemistry, or biology, typically with an advanced degree and experience in microscopy techniques. Familiarity with advanced fluorescence microscopy systems, data analysis software (such as ImageJ or MATLAB), and often certifications in laboratory safety are important. Attention to detail, problem-solving abilities, and effective communication help in troubleshooting experiments and collaborating with multidisciplinary teams. These skills are essential for generating accurate data, driving scientific discovery, and ensuring the reliability of experimental results.

What is the difference between Single Molecule Microscopy vs Fluorescence Microscopist?

AspectSingle Molecule MicroscopyFluorescence Microscopist
Required CredentialsAdvanced microscopy training, possibly PhD in biology or physicsSimilar; microscopy experience, often with a background in biology or chemistry
Work EnvironmentResearch labs, academic institutions, biotech companiesResearch labs, hospitals, biotech firms
Industry UsageSpecialized research in molecular biology, biophysicsBroad applications in cell biology, medical research

Single Molecule Microscopy and Fluorescence Microscopist roles share similar credentials and work environments, but Single Molecule Microscopy focuses on observing individual molecules, requiring specialized techniques. Fluorescence Microscopists often work with broader fluorescence imaging, making the roles distinct yet related in microscopy expertise.

What are popular job titles related to Single Molecule Microscopy jobs in Alabama?

For Single Molecule Microscopy jobs in Alabama, the most frequently searched job titles are:

Postdoctoral Fellow in Pulmonary Injury, Repair, and Fibrosis: Immune-Epithelial-Endothelial Niches

University of Alabama at Birmingham

Birmingham, AL

$45K - $62K/yr

Full-time

Posted 4 days ago


University Of Alabama At Birmingham rating

7.7

Company rating: 7.7 out of 10

Based on 44 frontline employees who took The Breakroom Quiz

265th of 631 rated colleges and universities


Job description

The University of Alabama at Birmingham invites applications for a Postdoctoral Fellow position in the Division of Pulmonary, Allergy, and Critical Care Medicine. The successful candidate will join a highly collaborative research program focused on pulmonary injury, repair, and fibrosis, with particular emphasis on immune cell-epithelial-endothelial niches that regulate lung remodeling and disease progression.

The laboratory uses mouse models of lung injury and fibrosis, human lung samples, alveolar epithelial organoids, flow cytometry, molecular and cellular biology, single-cell RNA-seq, spatial transcriptomics, and multi-omics approaches to define mechanisms of lung injury, repair failure, and fibrotic remodeling. Current projects investigate macrophage-epithelial-endothelial interactions, transitional epithelial cell states, vascular remodeling, inflammation, tissue repair, and therapeutic targets in pulmonary fibrosis. Please refer to related publications: Nat Commun. 16(1):1761. Commun Biol. 6(1):1047. Am J Respir Crit Care Med. 206(4):459-475.

The postdoctoral fellow will have opportunities to lead independent projects, develop new experimental and computational skills, publish high-impact manuscripts, present at national and international meetings, and prepare for an independent research career. The position provides a supportive training environment within a strong pulmonary research community at UAB.

Requirement

Applicants should have a strong interest in pulmonary biology, lung injury and repair, fibrosis, immunology, vascular biology, epithelial biology, or related areas. Prior experience in one or more of the following areas is preferred: mouse models, lung injury/fibrosis models, flow cytometry, immunostaining, confocal microscopy, organoid culture, molecular biology, single-cell RNA-seq, spatial transcriptomics, bioinformatics, or multi-omics data analysis.

The successful candidate should be highly motivated, scientifically curious, well organized, and able to work both independently and collaboratively. Strong written and oral communication skills are expected.

Interested applicants should submit a CV, a brief statement of research interests and career goals, and contact information for 2-3 references.

Gang Liu, MD, PhD | Professor

Moon H. Nahm, M.D. Endowed Chair

Division of Pulmonary, Allergy, and Critical Care Medicine

The University of Alabama at Birmingham

gangliu@uabmc.edu

http://www.uab.edu/medicine/pulmonary/faculty/liu


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About University of Alabama at Birmingham

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The University of Alabama at Birmingham is the heartbeat of Birmingham and an integral medical leader in the Southeast. The Birmingham campus is within walking distance of some of the best parks, entertainment, and dining in the region. UAB's three regional campuses expand their academic reach and responsibilities in addition to educating physicians in rural and underserved areas of the state. UAB is experiencing major and sustained investment and growth, due both to its exceptional research faculty and its culture of collaboration. Through concerted and strategic investments in its clinical and research enterprise, UAB has undergone an amazing transformation in the past five years and has strengthened its status and reputation as a leader in medical training, biomedical discovery, innovation, and patient care.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Birmingham, AL, US

Year founded

1859