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Single Molecule Microscopy Jobs in Virginia (NOW HIRING)

Virginia Tech

Postdoctoral Associate

Blacksburg, VA · On-site

... single-cell and spatial transcriptomics, and molecular biology approaches. The Postdoctoral ... fluorescence microscopy - Familiarity with basic molecular biology techniques (e.g., cloning ...

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Single Molecule Microscopy information

What is single molecule microscopy?

Single molecule microscopy is an advanced imaging technique that allows scientists to observe and analyze individual molecules in real time, often within living cells. Unlike traditional microscopy, which looks at the collective behavior of many molecules, this method provides detailed insights into molecular interactions, dynamics, and functions at the single-molecule level. It is widely used in biophysics, chemistry, and cell biology to study processes such as protein folding, enzyme activity, and molecular transport. This technique requires highly sensitive equipment and specialized fluorescent labeling to detect and track single molecules with great precision.

What are the key skills and qualifications needed to thrive as a single molecule microscopy specialist, and why are they important?

To thrive in Single Molecule Microscopy, you need a strong background in physics, chemistry, or biology, typically with an advanced degree and experience in microscopy techniques. Familiarity with advanced fluorescence microscopy systems, data analysis software (such as ImageJ or MATLAB), and often certifications in laboratory safety are important. Attention to detail, problem-solving abilities, and effective communication help in troubleshooting experiments and collaborating with multidisciplinary teams. These skills are essential for generating accurate data, driving scientific discovery, and ensuring the reliability of experimental results.

What is the difference between Single Molecule Microscopy vs Fluorescence Microscopist?

AspectSingle Molecule MicroscopyFluorescence Microscopist
Required CredentialsAdvanced microscopy training, possibly PhD in biology or physicsSimilar; microscopy experience, often with a background in biology or chemistry
Work EnvironmentResearch labs, academic institutions, biotech companiesResearch labs, hospitals, biotech firms
Industry UsageSpecialized research in molecular biology, biophysicsBroad applications in cell biology, medical research

Single Molecule Microscopy and Fluorescence Microscopist roles share similar credentials and work environments, but Single Molecule Microscopy focuses on observing individual molecules, requiring specialized techniques. Fluorescence Microscopists often work with broader fluorescence imaging, making the roles distinct yet related in microscopy expertise.

What are some common challenges faced by single molecule microscopy researchers, and how can they be addressed?

Single molecule microscopy researchers often encounter challenges such as minimizing background noise, achieving high-resolution imaging, and ensuring sample stability during prolonged observations. Addressing these issues typically involves optimizing sample preparation protocols, using advanced imaging techniques like Total Internal Reflection Fluorescence (TIRF) microscopy, and implementing robust data analysis tools. Collaborating closely with physicists, chemists, and bioinformaticians can also help troubleshoot technical hurdles and improve experimental outcomes.
What are popular job titles related to Single Molecule Microscopy jobs in Virginia? For Single Molecule Microscopy jobs in Virginia, the most frequently searched job titles are:
What job categories do people searching Single Molecule Microscopy jobs in Virginia look for? The top searched job categories for Single Molecule Microscopy jobs in Virginia are:
Single Molecule Microscopy jobs near you
Infographic showing various Single Molecule Microscopy job openings in Virginia as of August 2026, with employment types broken down into 1% Locum Tenens, 75% Full Time, 20% Part Time, and 4% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

Lab Specialist Intermediate, Ophthalmology

The Rector & Visitors of the University of Virginia

Charlottesville, VA • On-site

$50K/yr

Other

Re-posted 3 days ago

Job description

ALab Specialist Intermediateposition is available at the at the Department of Ophthalmology (IominiLab) at the The University of Virginia School of Medicine in Charlottesville, VA. The role requires a full-time commitment with compensation aligned with University of Virginia standards. Engaging in a research project and defending aMaster'sthesis is encouraged.

Research: Our laboratory studies morphogenesis and disease conditions of the mammalian eye. We specifically focus on understanding the signal transduction pathways involved in eye development, regeneration, and diseases using the mouse as a model system, combined with advanced two-photon microscopy and single-cell profiling.

Institute:We are part of the University of Virginia School of Medicine, which hosts an array of leading research institutes, centers, and facilities, offering interested candidates an interactive, highly collaborative, and innovative scientific environment that fosters strong interactions between basic and translational research.

We areseekinga highly motivated individual toassistpostdocs and the principal investigator in well-defined research projects sponsored by the National Eye Institute at NIH involving the use of two-photon confocal microscopy, mouse dissections, and genotyping following protocols available in the laboratory. Experience with mouse colonies, tissue culture, histological preparations, flow cytometry, confocal microscopy, and molecular cloning is highly desirable but notrequired. The candidate must be comfortable working with mice. Training in mouse handling and colony management will be provided.

Responsibilities

  • Assistlab memberswithmaintainingand organizing mouse strains involved in their assigned project.

  • Carry out basic histology tasks, including dissecting eye tissue, paraffin and plastic embedding, sectioning, and staining of embedded samples.

  • Assistwith experiments in immunofluorescence based on existing.

  • Assistwith lab organization, inventory management, record keeping, and ordering.

  • Actively enhance skills andexpertise.

  • Operatestandard equipment such as centrifuges, PCRmachinesand cell sorting equipment.

  • Responsible for laboratory maintenance, preparing solutions and media, and ordering supplies

  • Identifyand report problems in the completion of routine lab processes.

  • Update Excel sheets for lab inventory

Minimum Qualifications

  • Education: Bachelor's degreerequired.

  • Experience: 3+ years of relevant experience.

Preferred Qualifications

  • Willingness to work with experimental animals (mice).

  • Excellent analytical, organizational, communication, and computer skills.

Physical Demands

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals.Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.

Salary Range

  • Salary will be$50,000commensuratewith education and experience.

Position Type & Work Location

  • This is an exempt-level,benefitedposition. Learn more aboutUVA benefits.

  • This is a restricted position, which is dependent on funding and is contingent upon funding availability.

  • This position is based in Charlottesville, VA, and must be performed fully on-site.

About UVA and the Community

To learn more about UVA and in the Charlottesville area, visitUVA LifeandEmbark CVA.

Application Timeline

Application review will begin afterJune 17, 2026.

Additional Requirements

  • Background checks and pre-employment health screeningswill be conducted on all new hires prior to employment.

How to Apply

Please applyonline, by searching for requisition numberR0084316.

Internal applicantsmay search and apply for jobs on theUVA Internal Careers website.

Complete an application with the following documents:

  • Resume

  • Cover Letter

Upload all materials into the resume submissionfield. You cansubmitmultiple documents intothis onefield or combine them into one PDF.Applications without allrequireddocuments will notreceivefull consideration.

Reference Check Process

Reference checks will be completed by UVA's third-party partner, SkillSurvey, during the final phase of the interview. Five references will be requested, with at least three responsesrequired.

Contact

  • For questions about the application process, please contactJonFreeman, jf2sw@virginia.edu.

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment.

Apply