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Senior Statistical Programmer Jobs in Raleigh, NC

MedPharm

Sr. Process Engineer/Sr. Scientist

Durham, NC · On-site

$94K - $121K/yr

Job Summary The Sr. Process Engineer/Senior Scientist will lead late-stage development activities ... Evaluate process data and statistical trends to ensure process consistency and robustness.

MedPharm

Sr. Process Engineer/Sr. Scientist

Durham, NC · On-site

$94K - $121K/yr

Job Summary The Sr. Process Engineer/Senior Scientist will lead late-stage development activities ... Evaluate process data and statistical trends to ensure process consistency and robustness.

Pwc

CTIO - AI Engineer- Senior Manager

Raleigh, NC · On-site

$91K - $321K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... Engineer- Senior Manager, you will play a pivotal role in transforming raw data into actionable ... In this role, you will engage in exploratory and descriptive analysis, statistical modeling, and ...

New

NC SECU

Model Risk Analyst

Raleigh, NC · Hybrid

... senior validation staff. * (30%) Validate the performance and controls of statistical models using provided model development documentation and communications with model developers. Document and ...

GRAIL

Senior Engineer Operational Excellence #4891

Durham, NC · On-site

$94 - $125/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

For more information, please visit grail.com The Senior Engineer, Operational Excellence will ... Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve ...

Pharpoint Research

Director, Biostatistics

Durham, NC · On-site

Provide administrative and functional oversight for the biostatistics and statistical programming ... Provide accurate and timely status updates to other team members, colleagues, and senior management.

Eaton

Senior Systems Engineer

Raleigh, NC · On-site

$94K - $138K/yr

  • Medical

  • Retirement

The Senior Systems Engineer provides advanced engineering support for released critical power and ... Understanding of design evaluation techniques such as reliability analysis, statistical tolerance ...

GRAIL

Senior Engineer Operational Excellence #4891

Durham, NC · On-site

$94K - $125K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

For more information, please visit grail.com The Senior Engineer, Operational Excellence will ... Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve ...

GRAIL

Senior Engineer Operational Excellence #4891

Durham, NC · On-site

$94K - $125K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

For more information, please visit grail.com The Senior Engineer, Operational Excellence will ... Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve ...

GRAIL

Senior Engineer Operational Excellence #4891

Durham, NC · On-site

$94K - $125K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

For more information, please visit grail.com The Senior Engineer, Operational Excellence will ... Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve ...

MMS

Senior Biostatistician - Remote (US)

Raleigh, NC · On-site

Senior Biostatistician: Responsibilities: * Create randomization and kit schedules independently ... statistical analyses. * Strong SAS programming, SAS base, SAS macro experience. * Thorough ...

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All JobsStatistical Programmer JobsSenior Statistical Programmer JobsSenior Statistical Programmer Jobs in Raleigh, NC

Senior Statistical Programmer information

See Raleigh, NC salary details

$80.2K

$124.7K

$162.8K

How much do senior statistical programmer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior statistical programmer in Raleigh, NC is $124,705.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,000.00 and $143,900.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

What are the most commonly searched types of Statistical Programmer jobs in Raleigh, NC?

The most popular types of Statistical Programmer jobs in Raleigh, NC are:

What are popular job titles related to Senior Statistical Programmer jobs in Raleigh, NC?

For Senior Statistical Programmer jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Senior Statistical Programmer jobs in Raleigh, NC look for?

The top searched job categories for Senior Statistical Programmer jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Senior Statistical Programmer jobs?

Cities near Raleigh, NC with the most Senior Statistical Programmer job openings:

Senior Statistical Programmer jobs near you
Infographic showing various Senior Statistical Programmer job openings in Raleigh, NC as of August 2026, with employment types broken down into 75% Full Time, and 25% Contract. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $124,705 per year, or $60 per hour.

Sr. Process Engineer/Sr. Scientist

MedPharm

Durham, NC • On-site

$94K - $121K/yr

Full-time

Re-posted 3 days ago

Job description

Job Summary
The Sr. Process Engineer/Senior Scientist will lead late-stage development activities for topical and liquid oral pharmaceutical products, including process scale-up, technology transfer, commercial process validation, and manufacturing support. This role requires strong expertise in semisolid and liquid manufacturing processes, process robustness, troubleshooting, and regulatory compliance to support successful commercialization and lifecycle management.
Key Responsibilities
  • Lead late-stage formulation and process development activities for topical dosage forms (creams, ointments, gels, lotions) and liquid oral products (solutions, suspensions, syrups).
  • Design and execute scale-up, process optimization, and process characterization studies for commercial readiness.
  • Support technology transfer activities from R&D to pilot and commercial manufacturing sites, including CMOs/CDMOs.
  • Develop and review manufacturing process descriptions, batch manufacturing records (BMRs), process flow diagrams, and technical transfer documents.
  • Plan, execute, and document Process Performance Qualification (PPQ) and commercial process validation activities.
  • Provide technical oversight during exhibit, registration, validation, and commercial batches.
  • Troubleshooting issues related to mixing, homogenization, viscosity, phase separation, settling, aeration, filling, and hold time studies.
  • Technical support in investigations for deviations, OOS/OOT results, complaints, and CAPAs related to process or product performance.
  • Support cleaning validation, equipment qualification, and continued process verification (CPV) activities.
  • Collaborate closely with Analytical Development, Quality Assurance, Regulatory Affairs, Supply Chain, and Manufacturing teams.
  • Evaluate process data and statistical trends to ensure process consistency and robustness.
  • Support regulatory submissions, deficiency responses, audits, and inspections by providing technical documentation and SME support.
  • Ensure compliance with cGMP, FDA, EMA, ICH, and internal quality standards.

Required Qualifications
  • Master's or Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related scientific discipline.
  • 6-10+ years of experience in pharmaceutical development and manufacturing, with significant exposure to topical and liquid oral dosage forms.
  • Strong hands-on experience with semisolid and liquid manufacturing equipment including:
    • Homogenizers
    • Vacuum manufacturing vessels
    • Agitators and mixers
    • Colloid mills
    • Liquid filling equipment
  • Experience in process scale-up, technology transfer, and commercial process validation.
  • Thorough understanding of rheology, emulsion systems, suspension stability, viscosity control, and preservative systems.
  • Strong knowledge of cGMP, DOE, QbD principles, process validation lifecycle, and regulatory expectations.
  • Experience authoring and reviewing validation protocols, technical reports, and manufacturing investigations.
  • Excellent technical writing, communication, and cross-functional collaboration skills.

Preferred Skills
  • Experience with SUPAC guidelines for semisolid and liquid products.
  • Knowledge of preservative efficacy studies, hold time studies, and in-use stability considerations.
  • Familiarity with process analytical tools and statistical analysis software.
  • Experience supporting FDA/EMA audits and commercial product lifecycle management.
  • Exposure to scale-up challenges associated with emulsion and suspension systems.

Technical Expertise Areas
  • Emulsion and suspension manufacturing
  • Viscosity and rheology optimization
  • Mixing and homogenization scale-up
  • Process validation (PPQ)
  • Technology transfer documentation
  • Cleaning validation support
  • Continued Process Verification (CPV)
  • Manufacturing investigations and CAPA
  • Commercial manufacturing support

Typical Deliverables
  • Technology transfer protocols and reports
  • PPQ/Process validation protocols and reports
  • Manufacturing risk assessments
  • Scale-up and process characterization reports
  • Batch troubleshooting investigations
  • CPV trend analysis reports
  • Regulatory submission support documents
  • Hold time and mixing studies documentation

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