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Senior Python Software Engineer Jobs in San Diego, CA

Software Engineer, Sr

Poway, CA · On-site

$140 - $160/hr

To continue to meet our customer's mission critical needs, PDC is seeking a Software Engineer, Sr. ... Able to Develop and Maintain Python based desktop GUI applications to control and monitor Automated ...

Senior Software Engineer

San Diego, CA · On-site

$140K - $170K/yr

Senior Software Engineer The Mission: Do you want to build software that solves the world's most ... Python (for AI/Data integration) Logistics * Location: * Hybrid at one of STR's offices in Woburn ...

Sr Software Engineer - Accounting

San Diego, CA · On-site +1

$130K - $172K/yr

About this job We're looking for a Senior Software Engineer to join a 6-person cross-functional ... Knowledge of Ruby on Rails and experience working with a language like Ruby, Java, or Python.

Senior GPU Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

Qualcomm Graphics Software Engineers architect, design, implement, verify, and optimize the ... python) and ensures code will perform effectively on different platforms. • Maintains ...

Mid-Level Software Engineer Location: San Diego, CA (Onsite) Department: Software Engineering ... Design, develop, test, and maintain software applications primarily using C#, C++, and Python.

Senior Perception Software Engineer San Diego, CA (in-office) Salary Range: $180,000 - $250,000 ... Expert-level Python, with deep fluency in the scientific stack (NumPy, SciPy, OpenCV) and a track ...

Senior Software Engineer

San Diego, CA · On-site

$150 - $185/hr

Python on the backend and TypeScript/React on the frontend, with the freedom to reach for the right ... A full‑stack software engineering role (backend services, data, and frontend) where systems ...

Senior Perception Software Engineer Location: San Diego, CA (in-office) Salary Range: $180,000 ... Expert-level Python, with deep fluency in the scientific stack (NumPy, SciPy, OpenCV) and a track ...

Senior Perception Software Engineer Location: San Diego, CA (in-office) Salary Range: $180,000 ... Expert-level Python, with deep fluency in the scientific stack (NumPy, SciPy, OpenCV) and a track ...

Senior Perception Software Engineer Location: San Diego, CA (in-office) Salary Range: $180,000 ... Expert-level Python, with deep fluency in the scientific stack (NumPy, SciPy, OpenCV) and a track ...

Senior Staff Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

As a Senior Software Engineer, you will contribute to the design, development, and optimization and ... C++, Java, Python, etc. Preferred Qualifications: * Master's degree in Computer Science ...

Showing results 41-60

Senior Python Software Engineer information

See San Diego, CA salary details

$58.4K

$150.7K

$207K

How much do senior python software engineer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python software engineer in San Diego, CA is $150,737.00, according to ZipRecruiter salary data. Most workers in this role earn between $129,000.00 and $173,600.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by senior Python software engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a senior Python software engineer?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a senior Python software engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in San Diego, CA? For Senior Python Software Engineer jobs in San Diego, CA, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in San Diego, CA look for? The top searched job categories for Senior Python Software Engineer jobs in San Diego, CA are:
What cities near San Diego, CA are hiring for Senior Python Software Engineer jobs? Cities near San Diego, CA with the most Senior Python Software Engineer job openings:
Infographic showing various Senior Python Software Engineer job openings in San Diego, CA as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $150,737 per year, or $72.5 per hour.

Embedded Firmware Software Engineer

Innominds Software

San Diego, CA • On-site

$109K - $149K/yr

Other

Posted 10 days ago


Job description

Role: Embedded Firmware Software Engineer
Location: San Diego, CA
Duration: Fulltime

Qualifications:

  • embedded systems development with good experience in C++ programming.
  • Firmware Developement
  • Python packaging and scripting
  • Linux-based development environment
  • CI/CD pipelines
  • pytest framework

Thanks & Regards,

Jagga Rao

Senior Executive - International Consulting