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Senior Python Software Engineer Jobs in San Francisco, CA

INTELLISWIFT INC

Sr. Python Developer

San Francisco, CA

$143K - $192K/yr

Skill Python, Javascript, PostgreSQL, Node.js, Redis, iOS apps, Android apps Location San Francisco, CA Max Salary $ DOE Per Annum Employment Type Direct Jobs (Full Time) Description Engineers who ...

Fuku

Senior Software Engineer

San Francisco, CA · Hybrid

$180K - $220K/yr

Senior Software Engineer Location: San Francisco (hybrid, 3 days in-office; NYC option depending on ... B alance frontend (React/TypeScript) and backend (Python) responsibilities * C ollaborate closely ...

Fuku

Senior Software Engineer

San Francisco, CA · On-site

$180K - $220K/yr

Senior Software Engineer Location: San Francisco (hybrid, 3 days in-office; NYC option depending on ... backend (Python) responsibilities - Collaborate closely with the team to deliver impactful ...

CSG

Senior Software Engineer (Hardware Test)

San Francisco, CA · On-site

$130K - $169K/yr

Senior Software Engineer (Hardware Test) Location : San Francisco Bay Area, CA (Full-Time, Onsite ... Create automated test software using Python and Linux-based tools * Support integration, validation ...

Jobsbridge

Python Engineer

San Francisco, CA

ElasticSearch or Lucene - Experience in a fast-paced/customer-centric agile startup environmentSo, if you are a Senior Software Engineer with experience in Object-Oriented Python Development, please ...

Walmart

Python Senior Software Engineer

Hayward, CA · On-site

$117K - $234K/yr

Writes clean, efficient, and reliable code using languages such as JavaScript, TypeScript, Python ... Software Development, DevOps, Solution Design Respect the Individual: Demonstrates and encourages ...

Walmart

Python Senior Software Engineer

San Mateo, CA · On-site

$117K - $234K/yr

Writes clean, efficient, and reliable code using languages such as JavaScript, TypeScript, Python ... Software Development, DevOps, Solution Design Respect the Individual: Demonstrates and encourages ...

Technacity Group

Senior Software Engineer

Concord, CA · On-site

$134K - $177K/yr

Senior Software Engineer, Backend / Full Stack Cytronic | Concord, CA | Hybrid Cytronic is building ... You will work primarily in Python and Django while contributing across the product, infrastructure ...

Technacity Group

Senior Software Engineer

Concord, CA

$134K - $177K/yr

Senior Software Engineer, Backend / Full Stack Cytronic | Concord, CA | Hybrid Cytronic is building ... You will work primarily in Python and Django while contributing across the product, infrastructure ...

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Showing results 1-20

All JobsPython Software Engineer JobsSenior Python Software Engineer JobsSenior Python Software Engineer Jobs in San Francisco, CA

Senior Python Software Engineer information

See San Francisco, CA salary details

$64.8K

$167.3K

$229.7K

How much do senior python software engineer jobs pay per year?

As of Jul 28, 2026, the average yearly pay for senior python software engineer in San Francisco, CA is $167,272.00, according to ZipRecruiter salary data. Most workers in this role earn between $143,100.00 and $192,600.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in San Francisco, CA? For Senior Python Software Engineer jobs in San Francisco, CA, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in San Francisco, CA look for? The top searched job categories for Senior Python Software Engineer jobs in San Francisco, CA are:
What cities near San Francisco, CA are hiring for Senior Python Software Engineer jobs? Cities near San Francisco, CA with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer jobs near you
Infographic showing various Senior Python Software Engineer job openings in San Francisco, CA as of July 2026, with employment types broken down into 93% Full Time, 3% Part Time, and 4% Contract. Highlights an 88% Physical, 5% Hybrid, and 7% Remote job distribution, with an average salary of $167,272 per year, or $80.4 per hour.
Senior Python Developer- AI/ML

Senior Python Developer- AI/ML

Sustainable Talent

San Francisco, CA • On-site

$143K - $192K/yr

Full-time

PTO

Posted 2 days ago

Job description

Location: San Francisco, Bay Area, CA
Employment Type: Contract
About Us
Sustainable Talent provides flexible workforce solutions, connecting top-tier talent with leading global organizations. We partner with some of the world's most innovative companies to help them scale their teams with the right expertise. This opportunity is with one of our global high-tech clients, a leader in AI-driven technology and digital transformation. Our client is at the forefront of artificial intelligence, leveraging cutting-edge data science and machine learning to solve complex challenges.
About the Role
Our client is seeking a Python Developer to develop and optimize applications that support machine learning and data science initiatives. You'll work on building scalable data pipelines, deploying AI models, and ensuring performance and efficiency in production environments. Collaboration with data scientists and cross-functional teams will be key to transforming research into real-world solutions. If you're passionate about AI, cloud technologies, and writing clean, efficient code, this is an exciting opportunity to contribute to cutting-edge innovation.
What You'll Do
  • Develop and optimize Python-based applications that support data science and machine learning initiatives.
  • Implement and deploy machine learning models using TensorFlow, PyTorch, and Scikit-learn.
  • Design and build scalable data pipelines to preprocess and transform large datasets for AI/ML applications.
  • Work closely with data scientists to translate research into production-ready ML solutions.
  • Develop predictive analytics and deep learning solutions to enhance business intelligence and decision-making.
  • Ensure model performance optimization and scalability in production environments.
  • Integrate ML models into cloud-based platforms (AWS, GCP, Azure) and microservices architectures.
  • Write clean, efficient, and well-documented Python code following software engineering best practices.
  • Collaborate with cross-functional teams to drive innovation and improve AI-driven products.
What We're Looking For
  • 7+ years of software engineering experience with a strong focus on Python development.
  • Expertise in machine learning frameworks such as TensorFlow, PyTorch, and Scikit-learn.
  • Proficiency in data manipulation and processing libraries (Pandas, NumPy, SciPy).
  • Strong understanding of predictive analytics, deep learning, and AI model development.
  • Hands-on experience with big data processing technologies, including Spark, Hadoop, or Databricks.
  • Proficiency in cloud platforms (AWS, GCP, or Azure) and MLOps best practices.
  • Experience working with databases such as PostgreSQL, MySQL, MongoDB, or NoSQL databases.
  • Strong knowledge of data structures, algorithms, and software engineering principles.
  • Experience with API development and integrating AI models into scalable applications.
  • Proficiency in JavaScript and front-end frameworks (React, Vue, or Angular) is a plus.
  • Strong problem-solving skills and ability to communicate complex technical concepts effectively.
  • Bachelor's or Master's degree in Computer Science, Data Science, Engineering, or equivalent experience.
Why Join Us?
  • Work with a global high-tech AI-driven company leading in data science and machine learning.
  • Engage in high-impact AI/ML projects that drive innovation and business intelligence.
  • Competitive salary and career growth opportunities.
  • We offer full benefits, flexible PTO, and amazing company culture!
  • Be part of a diverse, inclusive, and collaborative work environment that fosters creativity and excellence.
How to Apply
If you're an experienced Senior Python Developer passionate about AI, machine learning, and data-driven innovation, we want to hear from you!
Apply today by submitting your resume and a brief cover letter detailing your relevant experience.
Sustainable Talent is an Equal Opportunity Employer and is committed to fostering an inclusive workplace. We prohibit discrimination and harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, or any other protected characteristic under applicable laws.

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