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Senior Python Software Engineer Jobs in San Francisco, CA

INTELLISWIFT INC

Sr. Python Developer

San Francisco, CA · On-site

$143K - $192K/yr

Skill Python, Javascript, PostgreSQL, Node.js, Redis, iOS apps, Android apps Location San Francisco, CA Max Salary $ DOE Per Annum Employment Type Direct Jobs (Full Time) Description Engineers who ...

Fuku

Senior Software Engineer

San Francisco, CA · Hybrid

$180K - $220K/yr

Senior Software Engineer Location: San Francisco (hybrid, 3 days in-office; NYC option depending on ... B alance frontend (React/TypeScript) and backend (Python) responsibilities * C ollaborate closely ...

Fuku

Senior Software Engineer

San Francisco, CA · On-site

$180K - $220K/yr

Senior Software Engineer Location: San Francisco (hybrid, 3 days in-office; NYC option depending on ... backend (Python) responsibilities - Collaborate closely with the team to deliver impactful ...

Walmart

Python Senior Software Engineer

Hayward, CA · On-site

$117K - $234K/yr

Writes clean, efficient, and reliable code using languages such as JavaScript, TypeScript, Python ... Software Development, DevOps, Solution Design Respect the Individual: Demonstrates and encourages ...

Walmart

Senior, Software Engineer - Python

San Mateo, CA · On-site

$117K - $234K/yr

Role summary: As a Senior Software Engineer, you will lead the delivery of scalable, secure ... Design, develop, test, and maintain data pipelines and platform services using Scala, Spark, Python ...

Walmart

Senior, Software Engineer - Python

Hayward, CA · On-site

$117K - $234K/yr

Role summary: As a Senior Software Engineer, you will lead the delivery of scalable, secure ... Design, develop, test, and maintain data pipelines and platform services using Scala, Spark, Python ...

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Senior Python Software Engineer information

See San Francisco, CA salary details

$64.8K

$167.3K

$229.7K

How much do senior python software engineer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for senior python software engineer in San Francisco, CA is $167,272.00, according to ZipRecruiter salary data. Most workers in this role earn between $143,100.00 and $192,600.00 per year, depending on experience, location, and employer.

What does a senior Python software engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

What are the key skills and qualifications needed to thrive as a senior Python software engineer?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What are some common challenges faced by senior Python software engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

Which senior Python software engineer job is in demand?

Senior Python software engineering roles are in high demand across industries such as technology, finance, and healthcare, especially for positions involving data analysis, machine learning, and web development. Skills in frameworks like Django or Flask, along with experience in cloud platforms and version control, enhance job prospects in this field.

What are popular job titles related to Senior Python Software Engineer jobs in San Francisco, CA?

For Senior Python Software Engineer jobs in San Francisco, CA, the most frequently searched job titles are:

What job categories do people searching Senior Python Software Engineer jobs in San Francisco, CA look for?

The top searched job categories for Senior Python Software Engineer jobs in San Francisco, CA are:

What cities near San Francisco, CA are hiring for Senior Python Software Engineer jobs?

Cities near San Francisco, CA with the most Senior Python Software Engineer job openings:

Senior Python Software Engineer jobs near you
Infographic showing various Senior Python Software Engineer job openings in San Francisco, CA as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 20% Part Time, and 3% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $167,272 per year, or $80.4 per hour.

Python Software Engineer (Jr-Mid Level)

Stellar IT Solutions LLC

Fremont, CA

$45 - $50/hr

Contractor

Posted 19 days ago

Job description

Python Software Engineer (Jr-Mid Level)6 months, with potential extension or conversionFremont, CA — 5 days onsite Role Summary

We are seeking a junior to mid‑level Python Software Engineer (3-5 years experience) to design, build, and optimize data‑intensive applications and machine learning solutions. The ideal candidate will come from fast‑paced technology companies (Amazon, Google, Microsoft, PayPal, Uber, Airbnb, Doordash, Expedia, etc.) and have a concise resume highlighting hands‑on coding contributions, debugging, troubleshooting, and distributed systems experience.

This role requires strong engineering fundamentals, recent hands‑on development, and the ability to clearly articulate technical contributions.

Responsibilities

  • Design, develop, and deploy LLM‑powered and AI‑driven applications.

  • Build scalable, high‑performance solutions using Python and modern engineering practices.

  • Develop and maintain REST APIs and microservices supporting critical business operations.

  • Work with diverse data sources (text, voice, image, structured datasets).

  • Collaborate with cross‑functional teams to identify opportunities for automation and optimization.

  • Own production systems: monitoring, troubleshooting, and continuous improvement.

  • Translate ambiguous business requirements into end‑to‑end technical solutions.

  • Write clean, maintainable, and reusable code following agile practices.

Must‑Have Requirements

  • 3-5 years of professional software engineering experience.

  • Bachelor’s or Master’s in Computer Science, Engineering, or equivalent practical experience.

  • Strong hands‑on Python experience for data‑intensive and high‑performance applications.

  • Experience building and deploying production machine learning solutions.

  • Demonstrated work with Large Language Models (LLMs) and Generative AI.

  • Experience developing REST APIs and microservices.

  • Proficiency with MySQL and Redis.

  • Familiarity with at least one deep learning framework (PyTorch, TensorFlow, JAX).

  • Strong fundamentals in statistics, data analysis, model evaluation, and performance optimization.

  • Clear examples of debugging, troubleshooting, and distributed systems problem‑solving.

Nice‑to‑Have Qualifications

  • Experience with recommender systems, operations research, or advanced AI/ML solutions.

  • Building and supporting enterprise‑scale ML platforms.

  • Working with large, complex datasets in production environments.

  • Knowledge of C# and ASP.NET (secondary skill).

  • Prior experience automating compliance frameworks and generating audit evidence.