1

Senior Python Software Engineer Jobs in San Diego, CA

Software Engineer

El Cajon, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

Software Engineer

La Jolla, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

#Senior Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

As a Senior Software Engineer, you will contribute to the design, development, and optimization and ... C++, Java, Python, etc. Preferred Qualifications: * Master's degree in Computer Science ...

Software Engineer

Rancho Santa Fe, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

Software Engineer

San Diego, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

Software Engineer

Cardiff By The Sea, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

Software Engineer

Chula Vista, CA · On-site

$87K - $157K/yr

Description Leidos Defense is seeking a Senior Software Engineer to develop and support the ... Create and maintain Python-based utilities and scripts to support system administration, testing ...

Senior Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

We are seeking a highly experienced and motivated Senior Software Engineer to contribute to the ... Expert programming skills in Python * Intermediate programming skills in Rust or Go * Experience ...

New

Senior Software Engineer

San Diego, CA · On-site

$124K - $164K/yr

We are seeking a highly experienced and motivated Senior Software Engineer to contribute to the ... Expert programming skills in Python * Intermediate programming skills in Rust or Go * Experience ...

New

Software Engineer, Sr

Poway, CA · On-site

$140K - $160K/yr

To continue to meet our customer's mission critical needs, PDC is seeking a Software Engineer, Sr. ... Able to Develop and Maintain Python based desktop GUI applications to control and monitor Automated ...

Software Engineer, Sr

Poway, CA · On-site

$140K - $160K/yr

To continue to meet our customer's mission critical needs, PDC is seeking a Software Engineer, Sr. ... Able to Develop and Maintain Python based desktop GUI applications to control and monitor Automated ...

Senior Software Engineer

San Diego, CA · On-site

$130K - $171K/yr

Senior Software Engineer Omega-KR, Inc. is a small but highly skilled group of engineers committed ... Java, Python, and/or Javascript * Solid understanding of Object-Oriented or Functional design ...

Software Engineer, Sr

Poway, CA · On-site

$140 - $160/hr

To continue to meet our customer's mission critical needs, PDC is seeking a Software Engineer, Sr. ... Able to Develop and Maintain Python based desktop GUI applications to control and monitor Automated ...

Senior Software Engineer

San Diego, CA · On-site

$120 - $150/hr

Senior Software Engineer Omega-KR, Inc. is a small but highly skilled group of engineers committed ... Java, Python, and/or Javascript * Solid understanding of Object-Oriented or Functional design ...

Software Engineer, Sr

Poway, CA · On-site

$140K - $160K/yr

To continue to meet our customers mission critical needs, PDC is seeking a Software Engineer, Sr. ... Able to Develop and Maintain Python based desktop GUI applications to control and monitor Automated ...

Showing results 21-40

Senior Python Software Engineer information

See San Diego, CA salary details

$58.4K

$150.7K

$207K

How much do senior python software engineer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python software engineer in San Diego, CA is $150,737.00, according to ZipRecruiter salary data. Most workers in this role earn between $129,000.00 and $173,600.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by senior Python software engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a senior Python software engineer?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a senior Python software engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in San Diego, CA? For Senior Python Software Engineer jobs in San Diego, CA, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in San Diego, CA look for? The top searched job categories for Senior Python Software Engineer jobs in San Diego, CA are:
What cities near San Diego, CA are hiring for Senior Python Software Engineer jobs? Cities near San Diego, CA with the most Senior Python Software Engineer job openings:
Infographic showing various Senior Python Software Engineer job openings in San Diego, CA as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $150,737 per year, or $72.5 per hour.

Software Engineer

Leidos

El Cajon, CA • On-site

$87K - $157K/yr

Full-time

Medical, Retirement, PTO

Re-posted 14 days ago


Leidos rating

8.3

Company rating: 8.3 out of 10

Based on 151 frontline employees who took The Breakroom Quiz

77th of 485 rated business services


Job description

Description

Leidos Defense is seeking a Senior Software Engineer to develop and support the virtualization of the AN/SQQ-89(V) Anti-Submarine (ASW) Training System by transitioning Tactical Insertion (TI) hardware-based solutions into a scalable, virtualized Linux platform for training. This role will design, implement, and sustain a high-performance virtualization environment utilizing Red Hat Enterprise Linux (RHEL), KVM, Open vSwitch (OVS), and hardware passthrough technologies to support complex Navy training and simulation workloads.

The ideal candidate should possess strong Linux systems engineering experience, expertise in virtualization and software automation, a deep understanding of low-level networking integration within mission-critical environments, and the ability to work within a complex Department of Defense (DoD) training and mission systems environment.

IMPACT: Works independently to achieve day-to-day objectives with significant impact on operational results. Responsible for SQQ 89 virtualization projects and complex ASW VOT maintenance/troubleshooting/repairs.

COMPLEXITY: Develops technical solutions that require collaboration with other internal experts, deep analyses and understanding of impact on customer training delivery. Develops solutions to technical problems and issues that may be unclear and require a deep-level of technical knowledge.

COMMUNICATION: Communicates with other project team members. Works to influence team members regarding solution design and processes.

KNOWLEDGE: Requires deep level understanding of principles and concepts of coding utilizing Red Hat Linux Enterprise (RHEL).

TYPICAL EDUCATION & EXPERIENCE: Typically requires BS degree with 4-8 years of prior relevant experience, or Master’s Degree with 2-6 years prior relevant experience.

Primary Responsibilities

  • Design, deploy, and maintain virtualized training system environments supporting AN/SQQ-89(V)15 training capabilities.

  • Migrate software and services from Tactical Insertion hardware platforms to virtualized infrastructures utilizing KVM, libvirt, virsh, and VirtIO technologies.

  • Develop and maintain automated deployment and configuration management solutions using Ansible.

  • Create and maintain Python-based utilities and scripts to support system administration, testing, monitoring, and data management activities.

  • Build and maintain RHEL 7/8 system images, templates, and repositories.

  • Troubleshoot virtualization, networking, storage, and operating system issues in lab and production environments.

  • Support software integration, system verification, validation, and acceptance testing activities.

  • Integrate physical and virtual network infrastructure supporting tactical training environments.

  • Configure and maintain Open vSwitch environments supporting multi-network and high-throughput virtual machine communications.

  • Support performance tuning and optimization of virtualized systems, networking, storage, and compute resources.

  • Collaborate with software developers, system engineers, cybersecurity personnel, and training system stakeholders to ensure successful implementation and sustainment.

  • Develop and maintain technical documentation including architecture diagrams, deployment guides, standard operating procedures, and automation documentation.

  • Support cybersecurity compliance efforts, including STIG implementation, vulnerability remediation, and RMF activities.

  • Participate in system modernization initiatives focused on increasing portability, scalability, and maintainability of training environments.

Desired Qualifications

  • Bachelor’s degree in Computer Science, Software Engineering, Computer Engineering, Information Systems, or related technical field.

  • 7+ years of experience in Linux systems engineering, virtualization, software development, or platform engineering.

  • Experience administrating Red Hat Enterprise Linux environments.

  • Strong experience with KVM virtualization technologies, libvirt, and virsh.

  • Experience implementing and troubleshooting Open vSwitch (OVS) deployments.

  • Experience with hardware passthrough technologies including PCIe passthrough, VFIO, SR-IOV, and IOMMU configuration.

  • Experience developing infrastructure automation using Ansible.

  • Experience developing software and automation tools using Python

  • Strong understanding of Linux network concepts including VLANs, bridges, routing, bonding, and virtual switching.

  • Experience troubleshooting complex integration issues across hardware, operating systems, networking, and applications.

  • Ability to obtain and maintain a DoD security clearance.

Preferred Qualifications

  • Experience supporting the AN/SQQ-89(V)15 or AEGIS combat systems suite.

  • Red Hat Certified Engineer (RHCE)

  • Experience with high-performance networking and low-latency virtualized environments.

  • Experience supporting GPU, FPGA, capture card, or specialized hardware passthrough to virtualized machines.

  • Familiarity with distributed storage, NFS, iSCSI, and SAN technologies.

  • Experience with FreeIPA, LDAP, Kerberos, and enterprise Linux identity management.

  • Experience supporting RMF, STIG implementation, ACAS, and cybersecurity compliance initiatives.

  • Active Secret or Top Secret clearance

If you're looking for comfort, keep scrolling. At Leidos, we outthink, outbuild, and outpace the status quo — because the mission demands it. We're not hiring followers. We're recruiting the ones who disrupt, provoke, and refuse to fail. Step 10 is ancient history. We're already at step 30 — and moving faster than anyone else dares.

Original Posting:June 9, 2026

For U.S. Positions: While subject to change based on business needs, Leidos reasonably anticipates that this job requisition will remain open for at least 3 days with an anticipated close date of no earlier than 3 days after the original posting date as listed above.

Pay Range:Pay Range $87,100.00 - $157,450.00

The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.

About Leidos

Leidos is an industry and technology leader serving government and commercial customers with smarter, more efficient digital and mission innovations. Headquartered in Reston, Virginia, with 47,000 global employees, Leidos reported annual revenues of approximately $16.7 billion for the fiscal year ended January 3, 2025. For more information, visit www.Leidos.com.

Pay and Benefits

Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available at www.leidos.com/careers/pay-benefits.

Securing Your Data

Beware of fake employment opportunities using Leidos’ name. Leidos will never ask you to provide payment-related information during any part of the employment application process (i.e., ask you for money), nor will Leidos ever advance money as part of the hiring process (i.e., send you a check or money order before doing any work). Further, Leidos will only communicate with you through emails that are generated by the Leidos.com automated system – never from free commercial services (e.g., Gmail, Yahoo, Hotmail) or via WhatsApp, Telegram, etc. If you received an email purporting to be from Leidos that asks for payment-related information or any other personal information (e.g., about you or your previous employer), and you are concerned about its legitimacy, please make us aware immediately by emailing us at LeidosCareersFraud@leidos.com.

If you believe you are the victim of a scam, contact your local law enforcement and report the incident to the U.S. Federal Trade Commission.

Commitment to Non-Discrimination

All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.


What Leidos employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Leidos logo

About Leidos

Sourced by ZipRecruiter

At Leidos, we deliver innovative solutions through the efforts of our diverse and talented people who are dedicated to our customers' success. We empower our teams, contribute to our communities, and operate sustainable practices. Everything we do is built on a commitment to do the right thing for our customers, our people, and our community.

Industry

It services

Company size

10,000+ Employees

Headquarters location

Reston, VA, US

Social media