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Senior Process Engineer Jobs in Rochester, MN (NOW HIRING)

Gilbane, Inc.

Sr VDC Engineer

Rochester, MN

$109K - $142K/yr

Gilbane is seeking a Senior VDC Engineer to lead constructability and coordination tasks on a project by using technology and processes. This role will sit in the office and on job sites as ...

Mayo Clinic

Senior IT Cloud Engineer

Rochester, MN · On-site

$56.75 - $75.75/hr

The IT Senior Cloud Engineer ensures that enterprise cloud solutions are optimized for cost and ... Creates and determines Cloud systems specifications, input/output processes and working parameters ...

New

Benchmark

Quality Engineer I

Rochester, MN · On-site

$73K - $94K/yr

Monitors manufacturing process, fabrication, inspection, test and shipping activities. Recommends ... senior engineers. • Ensures that records/files are initiated and maintained in all relevant ...

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All JobsProcess Engineer JobsSenior Process Engineer JobsSenior Process Engineer Jobs in Rochester, MN

Senior Process Engineer information

See Rochester, MN salary details

$76.2K

$123.1K

$173.3K

How much do senior process engineer jobs pay per year?

As of Jul 11, 2026, the average yearly pay for senior process engineer in Rochester, MN is $123,114.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,700.00 and $136,700.00 per year, depending on experience, location, and employer.

What is the difference between Senior Process Engineer vs Process Engineer?

AspectSenior Process EngineerProcess Engineer
QualificationsBachelor's or Master's in Engineering, often with 5+ years experienceBachelor's degree in Engineering or related field, typically 1-3 years experience
ResponsibilitiesLeading process improvements, mentoring, project managementSupporting process development, data analysis, assisting senior staff
Work EnvironmentDesign teams, manufacturing plants, R&D departmentsManufacturing facilities, engineering teams, operational support

Senior Process Engineers typically have more experience, leadership duties, and oversee complex projects, while Process Engineers focus on supporting process development and implementation. Both roles are essential in manufacturing and engineering industries, but the senior role involves greater responsibility and strategic planning.

What are the key skills and qualifications needed to thrive as a Senior Process Engineer, and why are they important?

To thrive as a Senior Process Engineer, you need a strong background in chemical or process engineering, problem-solving skills, and typically a bachelor's or master's degree in a relevant field. Expertise in process simulation software (such as Aspen Plus or HYSYS), Six Sigma or Lean certifications, and familiarity with process control systems are highly valued. Outstanding analytical abilities, leadership, and effective communication set top performers apart in this role. These skills and qualifications are crucial for optimizing processes, ensuring safety and compliance, and leading teams to achieve operational excellence.

What does a Senior Process Engineer do?

A Senior Process Engineer is responsible for designing, optimizing, and overseeing processes within manufacturing or production environments. They analyze workflows, troubleshoot issues, and implement improvements to increase efficiency, safety, and product quality. Senior Process Engineers often lead projects, mentor junior engineers, and collaborate with cross-functional teams to ensure operational excellence. Their expertise is vital in industries like chemicals, pharmaceuticals, oil and gas, and food processing.

What are some common challenges Senior Process Engineers face when working on cross-functional teams?

Senior Process Engineers often collaborate with professionals from various departments, such as operations, quality, and maintenance. A common challenge is aligning diverse priorities and communication styles to achieve shared project goals. Successfully managing these differences requires strong interpersonal and project management skills, as well as the ability to translate technical concepts for non-engineering colleagues. Regular meetings and clear documentation can help ensure everyone stays informed and engaged throughout the process.
What are the most commonly searched types of Process Engineer jobs in Rochester, MN? The most popular types of Process Engineer jobs in Rochester, MN are:
What are popular job titles related to Senior Process Engineer jobs in Rochester, MN? For Senior Process Engineer jobs in Rochester, MN, the most frequently searched job titles are:
What job categories do people searching Senior Process Engineer jobs in Rochester, MN look for? The top searched job categories for Senior Process Engineer jobs in Rochester, MN are:
What cities near Rochester, MN are hiring for Senior Process Engineer jobs? Cities near Rochester, MN with the most Senior Process Engineer job openings:
Senior Process Engineer jobs near you
Infographic showing various Senior Process Engineer job openings in Rochester, MN as of July 2026, with employment types broken down into 2% Locum Tenens, 90% Full Time, 5% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $123,114 per year, or $59.2 per hour.
Senior Engineer - Center of Regenerative Biotherapeutics

Senior Engineer - Center of Regenerative Biotherapeutics

Mayo Clinic

Rochester, MN • On-site

$148K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 4 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 688 frontline employees who took The Breakroom Quiz

105th of 881 rated healthcare providers

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

For the Center of Regenerative Biotherapeutics, the Senior Engineer designs and develops components of biomedical-related engineering systems, applying knowledge of complex principles, theories, concepts, tools and techniques to the design challenges -- Essentially we engineer solutions to manufacturing problems in cutting edge science but also problem solve a plethora of issues. Our Senior Engineer: 

  • Serves as a Technical Lead for projects
  • Provides technical and work direction to project team members and completes technical work as needed
  • Mentors and coaches other staff as required
  • May lead in evaluating new technologies and capital equipment
  • Understands and complies with relevant portions of Quality Management System
  • Has unit-specific expertise in safety risk management and continues to work to develop expertise in regulatory requirements applicable to his/her unit

Necessary skills: Self-starter who functions effectively in a multi-disciplinary development environment. Demonstrated ability to effectively communicate with team members, physicians and health care providers. Possesses effective oral communication and presentation skills. Develops engineering and technical documentation.


Qualifications

BS in Engineering or a related field (Biomedical Engineering preferred) and 5 years of professional engineering experience; Or MS in Engineering or related field and 3 year of professional engineering experience; Or, PhD in Engineering or related field and 1 year of professional engineering experience. 

Masters or PhD preferred, as well as early-to-mid career level candidates. 


Exemption Status
Exempt
Compensation Detail
99,070.40 - $148,616.00 / year; Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Mostly standard business hours. Some after work or before work may be needed. On-call rotation required.
Weekend Schedule
Rarely weekends however some circumstances may call for limited weekend hours.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'.  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter
Stephanie BairdQualifications:

BS in Engineering or a related field (Biomedical Engineering preferred) and 5 years of professional engineering experience; Or MS in Engineering or related field and 3 year of professional engineering experience; Or, PhD in Engineering or related field and 1 year of professional engineering experience. 

Masters or PhD preferred, as well as early-to-mid career level candidates. 

What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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