Senior Principal Engineer Jobs in Minnesota (NOW HIRING)

We anticipate the application window for this opening will close on - 10 Sep 2026
Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first - developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.
A Day in the Life
Senior Principal Software Engineer
Careers that Change Lives
Medtronic is a global leader in medical technology, services, and solutions that take on the healthcare industry's greatest challenges. Engineers and Scientists create our market-leading portfolio of innovations. Join the Coronary & Renal Denervation team and help us bring the next generation of life-changing medical technology to patients worldwide. At Medtronic, we push the limits of what technology can do to help alleviate pain, restore health, and extend life. We challenge ourselves and each other to make tomorrow better than yesterday. It is what makes this an exciting and rewarding place to be. Come for a job, stay for a career.
Treatments We Offer:
Renal Denervation
Key Technologies
Symplicity Spyral™ Renal Denervation (RDN) System
Medtronic's Coronary and Renal Denervation (CRDN) business is looking for a Senior Principal Software Engineer to be part of a high-performing team that is revolutionizing the design and development of energy based therapeutic medical devices to treat hypertension. In this role, you will leverage both your technical breadth and business acumen to support the next generation medical device software products.
This position is in Mounds View, MN. within the Coronary and Renal Denervation (CRDN) unit. At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges are invaluable to our work. We are working on-site 4 days per week as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary. This role will require less than 10% of travel to enhance collaboration and ensure successful completion of projects.
We believe that when people from different cultures, genders, and points of view come together, innovation is the result -and everyone wins. Medtronic walks the walk, creating an inclusive culture where you can thrive.
A Day in the Life
In general, the following responsibilities apply for the Senior Principal Software Engineer role. This includes, but is not limited to the following:
The Senior Principal Software Engineer will serve as the technical leader and be responsible for architecting, designing, building, and scaling embedded software for next generation medical device. This role combines deep hands-on engineering expertise with architectural leadership, technical decision-making, and mentorship.
The Senior Principal Engineer drives technical strategy, ensures engineering excellence, and partners closely with cross-functional teams and business stakeholders to deliver impactful solutions. In general, the following responsibilities apply for the Senior Principal Software Engineer role, this includes, but is not limited to the following:

• Architect, Design, develop, test, and maintain high-quality medical device embedded software solutions as part of the software team in accordance with Agile principles and Scrum methodologies
• Define and uphold architectural standards, design patterns, and best practices
• Make high-impact technical decisions that align with long-term platform and business strategy
• Review and guide system designs, APIs, data models, and integration approaches

• Optimize system performance, reliability, and scalability
• Ensure solutions meet security, privacy, and compliance requirements
• Lead Risk Assessment activities and Requirements development.
• Cross-functional team collaboration with HW and Systems partners, including integration team, testing team, Quality, System V&V...etc.

• Drive continuous improvement through retrospectives and lessons learned
• Provide leadership in solving engineering problems and fostering creativity and innovation in design and problem solutions
• Follow Medical device regulations (IEC 62304, IEC 82304, FDA...etc.)
• Stay up-to-date with industry trends and best practices in software development, and make recommendations for process improvements

The successful candidate will have:

• 10+ years of technical leadership experience
• Experience developing medical device software
• Strong expertise in programming languages (C++, Python, C#)
• Experience with various operating systems and tools - Linux OS, PetaLinux, Yocto, FreeRTOS
• Experience with Containers
• Strong knowledge of secure SDLC practices and software risk management

Qualifications -
Must Have - Minimum Requirements
TO BE CONSIDERED FOR THIS ROLE, PLEASE BE SURE THE MINIMUM REQUIREMENTS ARE EVIDENT ON YOUR RESUME

• Bachelor's degree in computer engineering, electrical engineering, computer science, engineering, or a related technical discipline and minimum of 10 years of work experience OR advanced degree in computer engineering, electrical engineering, computer science, engineering, or a related technical discipline with 8 years of work experience.

Nice to Have

• Knowledge of microservices architecture and event-driven systems
• Familiarity with FPGA
• Experience in regulated or enterprise-scale environments
• Knowledge of cloud and connected medical devices
• Excellent collaboration skills across engineering, quality, and regulatory teams
• Pragmatic decision-making that balances compliance, security, and delivery velocity
• Clear communication with both technical and non-technical stakeholders

About Medtronic
Together, we can change healthcare worldwide. At Medtronic, we push the limits of what technology, therapies and services can do to help alleviate pain, restore health, and extend life. We challenge ourselves and each other to make tomorrow better than yesterday. It is what makes this an exciting and rewarding place to be.
We want to accelerate and advance our ability to create meaningful innovations - but we will only succeed with the right people on our team. Let's work together to address universal healthcare needs and improve patients' lives. Help us shape the future.
Physical Job Requirements
The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role. (ADA-United States of America)
For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.
Physical Job Requirements
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.
The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.
U.S. Work Authorization & Sponsorship
At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.
Recruitment Fraud Alert
We are aware of phishing scams targeting job seekers. Please keep the following in mind:
Apply only through official Medtronic channels. All legitimate Medtronic recruiting communications come from approved Medtronic platforms and official @medtronic.com email addresses.
Medtronic will never ask for payment or sensitive personal information (such as bank account or Social Security details) during early stages of the hiring process. Any such requests are not legitimate.
If you receive a suspicious message claiming to be from Medtronic, do not respond, click links, or open attachments.
If you have any questions, concerns regarding the authenticity of a communication alleged to have been made by or on behalf of Medtronic, please contact us immediately at AskHR@medtronic.com.
Benefits & Compensation
Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.
Salary ranges for U.S (excl. PR) locations (USD):$178,400.00 - $267,600.00
This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP).
The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).
The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).
The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).
Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.
Further details are available at the link below:
Medtronic benefits and compensation plans
It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.
If you are applying to perform work for Medtronic, Inc. ("Medtronic") in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.