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Senior Metabolic Engineer Jobs (NOW HIRING)

Becoming

Optics Engineer

San Francisco, CA · On-site

$151K - $196K/yr

We are building systems that don't - by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Becoming

Optics Engineer

San Francisco, CA · On-site

$151K - $196K/yr

We are building systems that don't -- by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Becoming

Optics Engineer

San Francisco, CA

$152K - $196K/yr

We are building systems that don't - by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Monogram Health

Senior Machine Learning Engineer

$125K - $165K/yr

Senior Machine Learning Engineer The Senior Machine Learning Engineer will be responsible for the ... and other metabolic disorders. Monogram Health employs a robust clinical team, leveraging ...

Twin Health

Senior AI Applications Engineer

$195K - $210K/yr

Opportunity We are looking for a Senior AI Applications Engineer to join our team and play a key ... metabolic well-being. Responsibilities * Lead the design, development, and deployment of ...

Mochi Health

Senior Front-End Engineer

San Francisco, CA

$144K - $198K/yr

We are looking for a Senior Frontend Engineer to own the interfaces that our patients and medical ... Mochi has already helped patients lose over 5 million pounds through metabolic care, and we are now ...

Mochi Health

Senior Front-End Engineer

San Francisco, CA · On-site

$144K - $198K/yr

We are looking for a Senior Frontend Engineer to own the interfaces that our patients and medical ... Mochi has already helped patients lose over 5 million pounds through metabolic care, and we are now ...

Mochi Health

Senior Front-End Engineer

San Francisco, CA

$144K - $198K/yr

We are looking for a Senior Frontend Engineer to own the interfaces that our patients and medical ... Mochi has already helped patients lose over 5 million pounds through metabolic care, and we are now ...

Medpace, Inc.

Senior Data Engineer

Cincinnati, OH · On-site

$101K - $138K/yr

... based Senior Data Engineer to join our Information Technology team. This position will work on a ... metabolic, endocrinology, central nervous system, and anti-viral and anti-infective. Headquartered ...

Gehc

Engineering Program Manager - Xray

Madison, WI · On-site

$130K/yr

Summary GE Healthcare's Bone and Metabolic Health (BMH) business is seeking a dynamic Program ... Act as the primary point of contact for internal teams, senior leadership, and external partners (e ...

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Senior Metabolic Engineer information

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$59.5K

$126.6K

$183.5K

How much do senior metabolic engineer jobs pay per year?

As of Sep 2, 2026, the average yearly pay for senior metabolic engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What is a senior metabolic engineer?

A Senior Metabolic Engineer is a highly skilled professional who designs, optimizes, and manipulates the metabolic pathways of microorganisms or cells to produce desired compounds, such as biofuels, pharmaceuticals, or specialty chemicals. They use advanced techniques in genetic engineering, systems biology, and computational modeling to improve the efficiency and yield of biological production processes. Senior Metabolic Engineers often lead research projects, mentor junior scientists, and collaborate with cross-functional teams to solve complex challenges in biotechnology or industrial microbiology.

What are some of the main challenges senior metabolic engineers face when scaling up laboratory successes to industrial production?

One of the key challenges for Senior Metabolic Engineers is ensuring that metabolic pathways optimized in the lab remain robust and efficient at industrial scales. Factors such as changes in oxygen transfer, nutrient gradients, and bioreactor conditions can significantly affect organism performance. Additionally, addressing issues like byproduct accumulation, strain stability, and process economics is crucial for successful scale-up. Collaborating closely with process engineers, bioprocess technicians, and quality control teams is essential to troubleshoot and optimize these transitions.

What are the key skills and qualifications needed to thrive as a senior metabolic engineer, and why are they important?

To thrive as a Senior Metabolic Engineer, you need advanced knowledge in metabolic engineering, biochemical pathways, and molecular biology, typically supported by a Ph.D. or Master's degree in a related field. Familiarity with tools such as metabolic modeling software (e.g., COBRApy), genetic engineering techniques, and analytical instruments like HPLC or GC-MS is crucial. Strong problem-solving skills, teamwork, and effective communication help distinguish top performers in this role. These competencies are vital for designing, optimizing, and scaling biological systems to achieve innovative and commercially viable solutions.

What is the difference between Senior Metabolic Engineer vs Metabolic Engineer?

AspectSenior Metabolic EngineerMetabolic Engineer
Required CredentialsBachelor's/Master's in Bioengineering, Biochemistry, or related; experience preferredBachelor's or higher in related field; entry to mid-level experience
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsResearch and development, biotech startups, academia
Employer & Industry UsageUsed in biotech, pharma, and research institutions for advanced projectsCommon in biotech and research settings for foundational work

The main difference between a Senior Metabolic Engineer and a Metabolic Engineer lies in experience and responsibility. Senior roles typically involve leading projects, mentoring, and advanced problem-solving, while Metabolic Engineers focus on executing experiments and supporting research. Both roles are vital in biotech and pharmaceutical industries, but the senior position requires more expertise and leadership experience.

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What cities are hiring for Senior Metabolic Engineer jobs?

Cities with the most Senior Metabolic Engineer job openings:

What are the most commonly searched types of Metabolic Engineer jobs?

The most popular types of Metabolic Engineer jobs are:

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States with the most job openings for Senior Metabolic Engineer jobs include:

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Senior Metabolic Engineer jobs near you
Infographic showing various Senior Metabolic Engineer job openings in the United States as of August 2026, with employment types broken down into 93% Full Time, 3% Part Time, and 4% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

Optics Engineer

Becoming

San Francisco, CA • On-site

$151K - $196K/yr

Full-time

Re-posted 12 days ago

Job description

About Becoming
Becoming is building Developmental Intelligence: AI for predicting how organisms change over time.
Most experimental systems fail when metabolic demands become too high. We are building systems that don't - by combining engineered metabolic environments, sensing, control, and software into tightly integrated products that operate reliably over long time horizons.
Hardware is core to our platform. It must work continuously, predictably, and under real biological constraints.
The Role
We are hiring an Optics Engineer to architect and own optical subsystems within Becoming's integrated hardware platform.
This is a senior builder role. You will design stable, production-grade optical systems that integrate tightly with mechanical structures, electronics, firmware, and data systems - and you will be accountable for their real-world performance.
This is not a research imaging role. You will think in terms of alignment stability, signal integrity, manufacturability, and long-duration runtime.
You will define specifications, make architecture decisions, and own outcomes.
What You'll Own
  • End-to-end ownership of optical subsystems inside complex hardware platforms
  • Optical path architecture: illumination, detection, filtering, and signal optimization
  • Component selection with attention to stability, lifecycle, and manufacturability
  • Mechanical integration and alignment strategy under thermal and environmental constraints
  • Electrical integration of detectors and signal acquisition systems
  • Signal-to-noise optimization and drift mitigation
  • Calibration frameworks and long-term stability validation
  • Prototyping, stress testing, and failure analysis
  • Documentation and standards that enable scaling

Who You Are
You are someone who:
  • Operates with high agency - you identify problems, define solutions, and execute
  • Takes end-to-end ownership of what you build
  • Brings high energy to complex, ambiguous engineering challenges
  • Acts with high integrity - you are honest about tradeoffs, risks, and failure modes
  • Communicates directly and clearly, especially when something won't work
  • Is self-aware about your strengths and gaps, and proactively fills them
  • Thinks like a systems integrator, not a narrow specialist
  • Cares deeply about understanding systems at a first-principles level

Requirements
  • Have built optical systems that operated outside of controlled lab demos
  • Think in systems, not just ray traces
  • Understand how optical decisions impact mechanical tolerances and electrical noise
  • Surface limitations and risks clearly
  • Prefer robust architectures over fragile precision
  • Stay composed debugging signal degradation in live systems
  • Raise the technical bar around you
  • You take responsibility for whether the signal holds up over time - not just whether the design simulated correctly.

Strong Signals
  • Degree in optics, physics, electrical engineering, or equivalent demonstrated depth
  • Experience designing and shipping integrated optical systems
  • Strong first-principles understanding of optical design and detection physics
  • Experience integrating optics with mechanical and electrical platforms
  • Demonstrated ownership of systems operating under real-world constraints
  • Ability to operate without rigid process scaffolding or heavy vendor abstraction

Benefits
  • Competitive salary and meaningful equity
  • Full benefits
  • High-trust, high-ownership environment
  • Rapid growth in scope and responsibility

Apply