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Senior Metabolic Engineer Jobs (NOW HIRING)

Orchestra Bio, Inc

Senior Platform Engineer

San Francisco, CA · On-site

$123K - $169K/yr

... metabolic disease, and biomanufacturing. We're looking for engineers who are excited about building ... The Role We're seeking a Senior Platform Engineer to join our growing team in San Francisco. You'll ...

Orchestra Bio, Inc

Senior Fullstack Engineer

San Francisco, CA · On-site

$144K - $190K/yr

... metabolic disease, and biomanufacturing. We're looking for engineers who are excited about building ... The Role We're seeking a Senior Fullstack Engineer to join our growing team in San Francisco. You ...

Allara

Senior Engineering Manager

New York, NY · Remote

$225K - $262K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Allara is hiring a Senior Engineering Manager to lead and grow a team of engineers building the technology that powers expert, longitudinal care for women's hormonal, metabolic, and reproductive ...

Allara Health

Senior Engineering Manager

New York, NY · On-site

$225K - $262K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Allara is hiring a Senior Engineering Manager to lead and grow a team of engineers building the technology that powers expert, longitudinal care for women's hormonal, metabolic, and reproductive ...

Becoming

Optics Engineer

San Francisco, CA · On-site

$151K - $196K/yr

We are building systems that don't - by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Becoming

Optics Engineer

San Francisco, CA · On-site

$151K - $196K/yr

We are building systems that don't -- by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Becoming

Optics Engineer

San Francisco, CA · On-site

$100 - $130/hr

We are building systems that don't -- by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production‑grade optical systems that ...

Icehouseventures

Optics Engineer

San Francisco, CA · On-site

$100 - $130/hr

We are building systems that don't -- by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production‑grade optical systems that ...

Becoming

Optics Engineer

San Francisco, CA · On-site

$152K - $196K/yr

We are building systems that don't - by combining engineered metabolic environments, sensing ... This is a senior builder role. You will design stable, production-grade optical systems that ...

Twin Health

Senior Salesforce Technical Consultant, GTM

$128K - $157K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... in metabolic health. Opportunity We are looking for a Senior Salesforce Technical Consultant to join our team. In this role, you will be a key architect and developer responsible for designing ...

Allara

Senior Software Engineer

Manhattan, NY · On-site

$175 - $205/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... of hormonal, metabolic, and reproductive care. Allara provides ongoing support for hormonal ... The Opportunity We're looking for a Senior Software Engineer to help build features that directly ...

Allara

Senior Software Engineer

New York, NY · Remote

$175K - $205K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... of hormonal, metabolic, and reproductive care. Allara provides ongoing support for hormonal ... The Opportunity We're looking for a Senior Software Engineer to help build features that directly ...

Allara Health

Senior Software Engineer

New York, NY · On-site

$175K - $205K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... of hormonal, metabolic, and reproductive care. Allara provides ongoing support for hormonal ... The Opportunity We're looking for a Senior Software Engineer to help build features that directly ...

Mochi Health

Senior Front-End Engineer

San Francisco, CA · On-site

$144K - $198K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for a Senior Frontend Engineer to own the interfaces that our patients and medical ... Mochi has already helped patients lose over 5 million pounds through metabolic care, and we are now ...

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Showing results 21-40

All JobsMetabolic Engineer JobsSenior Metabolic Engineer Jobs

Senior Metabolic Engineer information

See salary details

$59.5K

$126.6K

$183.5K

How much do senior metabolic engineer jobs pay per year?

As of Aug 13, 2026, the average yearly pay for senior metabolic engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What is the difference between Senior Metabolic Engineer vs Metabolic Engineer?

AspectSenior Metabolic EngineerMetabolic Engineer
Required CredentialsBachelor's/Master's in Bioengineering, Biochemistry, or related; experience preferredBachelor's or higher in related field; entry to mid-level experience
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsResearch and development, biotech startups, academia
Employer & Industry UsageUsed in biotech, pharma, and research institutions for advanced projectsCommon in biotech and research settings for foundational work

The main difference between a Senior Metabolic Engineer and a Metabolic Engineer lies in experience and responsibility. Senior roles typically involve leading projects, mentoring, and advanced problem-solving, while Metabolic Engineers focus on executing experiments and supporting research. Both roles are vital in biotech and pharmaceutical industries, but the senior position requires more expertise and leadership experience.

What is a senior metabolic engineer?

A Senior Metabolic Engineer is a highly skilled professional who designs, optimizes, and manipulates the metabolic pathways of microorganisms or cells to produce desired compounds, such as biofuels, pharmaceuticals, or specialty chemicals. They use advanced techniques in genetic engineering, systems biology, and computational modeling to improve the efficiency and yield of biological production processes. Senior Metabolic Engineers often lead research projects, mentor junior scientists, and collaborate with cross-functional teams to solve complex challenges in biotechnology or industrial microbiology.

What are some of the main challenges senior metabolic engineers face when scaling up laboratory successes to industrial production?

One of the key challenges for Senior Metabolic Engineers is ensuring that metabolic pathways optimized in the lab remain robust and efficient at industrial scales. Factors such as changes in oxygen transfer, nutrient gradients, and bioreactor conditions can significantly affect organism performance. Additionally, addressing issues like byproduct accumulation, strain stability, and process economics is crucial for successful scale-up. Collaborating closely with process engineers, bioprocess technicians, and quality control teams is essential to troubleshoot and optimize these transitions.

What are the key skills and qualifications needed to thrive as a senior metabolic engineer, and why are they important?

To thrive as a Senior Metabolic Engineer, you need advanced knowledge in metabolic engineering, biochemical pathways, and molecular biology, typically supported by a Ph.D. or Master's degree in a related field. Familiarity with tools such as metabolic modeling software (e.g., COBRApy), genetic engineering techniques, and analytical instruments like HPLC or GC-MS is crucial. Strong problem-solving skills, teamwork, and effective communication help distinguish top performers in this role. These competencies are vital for designing, optimizing, and scaling biological systems to achieve innovative and commercially viable solutions.
More about Senior Metabolic Engineer jobs
What cities are hiring for Senior Metabolic Engineer jobs? Cities with the most Senior Metabolic Engineer job openings:
What are the most commonly searched types of Metabolic Engineer jobs? The most popular types of Metabolic Engineer jobs are:
What states have the most Senior Metabolic Engineer jobs? States with the most job openings for Senior Metabolic Engineer jobs include:
What job categories do people searching Senior Metabolic Engineer jobs look for? The top searched job categories for Senior Metabolic Engineer jobs are:
Senior Metabolic Engineer jobs near you
Infographic showing various Senior Metabolic Engineer job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 2% Part Time, and 6% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

Senior Platform Engineer

Orchestra Bio, Inc

San Francisco, CA • On-site

$123K - $169K/yr

Full-time

Re-posted 26 days ago

Job description

About Orchestra
Orchestra helps companies navigate the journey from discovery to medicine by connecting science, operations, and finance in an intelligent platform. We're on a mission to make every R&D dollar count.
Developing new medicines is a societal imperative to improve human health and reduce medical costs. Brilliant science needs effective management to develop breakthrough medicines that reach patients. We aim to bring the same level of sophistication to scientific development that modern tools brought to software development. While software teams can ship updates daily, R&D organizations face unique challenges: years long development cycles, complex interdependencies, and high-stakes decisions that can make or break billion dollar programs.
Founded by early Benchling leaders, we just emerged from stealth with $20M in funding from 8VC, Andreessen Horowitz, Insight Partners, Definition, and Haystack to transform how biotech companies operate. Our customers are working on society's most important challenges, including neurodegeneration, cancer, metabolic disease, and biomanufacturing. We're looking for engineers who are excited about building software that helps scientific organizations operate more effectively.
The Role
We're seeking a Senior Platform Engineer to join our growing team in San Francisco. You'll build and maintain the foundational infrastructure that powers Orchestra's intelligent R&D management platform, ensuring our systems can scale reliably as we help more companies bring breakthrough innovations to market.
Challenges You'll Tackle
Mission Critical Infrastructure: Design and maintain the cloud infrastructure that biotech companies depend on for managing billion dollar R&D programs. Build systems that handle sensitive scientific data, complex financial modeling, and AI workloads with the reliability and security these high stakes operations demand.
Scalable AI Operations: Create the platform infrastructure that powers our AI driven signals extraction from meeting transcripts, documents, and operational data. Design systems that can process unstructured data at scale while maintaining performance and cost efficiency as our customer base grows.
Developer Experience: Create tooling and infrastructure that enables our engineering team to ship features rapidly and reliably. Design CI/CD pipelines, monitoring systems, and development environments that help us maintain quality while moving at startup speed.
Security & Compliance: Implement infrastructure that meets the stringent requirements of biotech and pharmaceutical companies. Build towards SOC 2 compliance while maintaining the development velocity needed in a fast-growing startup environment.
What Sets You Apart
Complexity: You understand how to build platform infrastructure for complex, data-intensive applications where reliability directly impacts scientific outcomes. You're excited about the technical challenges of supporting AI workloads, financial modeling, and secure data processing at scale.
Curiosity: You're genuinely curious about how breakthrough products are developed and excited about building infrastructure that helps scientific organizations operate more effectively. You want your platform work to contribute to bringing medicines and other innovations to market.
Agency: You're drawn to environments where you can shape both the technical infrastructure and operational practices. You enjoy the responsibility of building foundational systems that will scale, balancing the speed needed at an early stage company with the reliability required for mission critical software.
Qualifications
Required
  • 5+ years of platform/infrastructure engineering or SRE experience
  • Strong expertise in cloud infrastructure (AWS/GCP/Azure) including IaC tools (Terraform, CloudFormation)
  • Hands-on experience with monitoring and observability, implementing and running alerting systems and incident response
  • Hands-on experience with CI/CD pipeline design, implementation and maintenance
  • Collaborative mindset with proven track record of working effectively in small, fast-moving engineering teams

Preferred
  • SOC 2 compliance implementation experience: security controls, monitoring, audit preparation
  • Performance optimization experience for data intensive applications
  • AI-assisted development proficiency; leveraging tools to accelerate infrastructure work

Apply