1

Senior Interoperability Engineer Jobs (NOW HIRING)

Senior Systems Engineer

Huntsville, AL · On-site

$105K - $143K/yr

Senior Systems Engineer Company Overview: KODA is a people-first company recognized as a seven-time ... Experience with Interface or Interoperability engineering domain Desired Qualifications:

$250/hr

Interoperability touches Clinical, Operations, Engineering, Data, Legal, and Compliance; you'll ... Translate a fast-moving, complex interoperability landscape into clear decisions for senior ...

Summary Position Highlights The Workday Interoperability Engineer serves as a senior technical expert responsible for architecting, deploying, and maintaining Workday integrations and ...

The Workday Interoperability Engineer serves as a senior technical expert responsible for architecting, deploying, and maintaining Workday integrations and interoperability frameworks that support ...

$108K - $165K/yr

The Workday Interoperability Engineer serves as a senior technical expert responsible for architecting, deploying, and maintaining Workday integrations and interoperability frameworks that support ...

Senior Systems Engineer

Huntsville, AL · On-site

$108K - $148K/yr

Responsibilities PeopleTec is currently seeking a Senior Systems Engineer to support our Huntsville ... Experience with Interface or Interoperability engineering domains * Must be a U.S. Citizen * An ...

Interoperability touches Clinical, Operations, Engineering, Data, Legal, and Compliance; you'll ... Translate a fast-moving, complex interoperability landscape into clear decisions for senior ...

Showing results 21-40

Senior Interoperability Engineer information

See salary details

$59.5K

$126.6K

$183.5K

How much do senior interoperability engineer jobs pay per year?

As of Sep 8, 2026, the average yearly pay for senior interoperability engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What is a senior interoperability engineer?

A Senior Interoperability Engineer is a specialized professional who ensures that different software systems, applications, or devices can effectively communicate and work together. They design, implement, and maintain integration solutions, often in complex environments such as healthcare, finance, or enterprise IT. This role typically involves working with APIs, data standards, and protocols to facilitate seamless data exchange between systems. Senior Interoperability Engineers also troubleshoot integration issues, ensure compliance with industry standards, and may lead or mentor junior engineers. Their expertise helps organizations maximize operational efficiency by eliminating data silos and improving system connectivity.

What are the key skills and qualifications needed to thrive as a senior interoperability engineer?

To thrive as a Senior Interoperability Engineer, you need expertise in healthcare data standards (such as HL7, FHIR, and CDA), system integration, and a degree in computer science or a related field. Familiarity with integration engines (like Mirth Connect or Cloverleaf), API development, and relevant certifications (e.g., HL7 or FHIR Proficiency) is typically required. Strong problem-solving abilities, communication, and project management skills help bridge technical gaps across teams and stakeholders. These competencies are crucial for ensuring seamless data exchange, regulatory compliance, and improved healthcare outcomes through robust interoperability solutions.

How does a senior interoperability engineer typically collaborate with cross-functional teams during integration projects?

Senior Interoperability Engineers frequently work alongside software developers, system architects, business analysts, and IT operations staff to ensure smooth integration between disparate systems. They are often responsible for leading technical discussions, clarifying data exchange requirements, and troubleshooting complex issues that arise during implementation. Strong communication and documentation skills are essential, as these engineers must translate technical details for both technical and non-technical stakeholders. Collaboration is typically facilitated through regular meetings, project management tools, and shared documentation platforms.

What is the difference between Senior Interoperability Engineer vs Network Engineer?

AspectSenior Interoperability EngineerNetwork Engineer
CredentialsBachelor's in CS or related, certifications like HL7, FHIR, Cisco (CCNA)Bachelor's in CS, EE, or related, Cisco certifications (CCNA, CCNP)
Work EnvironmentHealthcare IT, software integration, systems interoperabilityNetworking infrastructure, enterprise networks, data centers
Industry UsageHealthcare, health IT, software vendorsTelecommunications, IT services, enterprise organizations
Comparison FocusIntegrating healthcare systems and standardsDesigning and managing network infrastructure

The main difference is that a Senior Interoperability Engineer focuses on integrating healthcare systems and standards, while a Network Engineer manages network infrastructure. Both roles require technical certifications and work in IT environments, but their industry focus and daily tasks differ significantly.

More about Senior Interoperability Engineer jobs

What cities are hiring for Senior Interoperability Engineer jobs?

Cities with the most Senior Interoperability Engineer job openings:

What are the most commonly searched types of Interoperability Engineer jobs?

The most popular types of Interoperability Engineer jobs are:

What states have the most Senior Interoperability Engineer jobs?

States with the most job openings for Senior Interoperability Engineer jobs include:

What are popular job titles related to Senior Interoperability Engineer jobs?

For Senior Interoperability Engineer jobs, the most frequently searched job titles are:

Infographic showing various Senior Interoperability Engineer job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 92% Full Time, 3% Part Time, and 4% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

Leo Cancer Care: Senior Software Engineer - Interoperability

Middleton, WI • On-site

$125K - $165K/yr

Full-time

Re-posted 19 days ago


Job description

Position Title: Senior Software Engineer - Interoperability
Reports to: Senior Manager Global Software Engineering
FT/PT : Full-time
Location : US Office, Hybrid- Office 3 days a week
Position Summary: Join our dynamic engineering team to help develop our revolutionary radiotherapy products for upright therapy. This role sits at the intersection of medical device software engineering and clinical systems integration, with a primary focus on DICOM-RT interoperability between our treatment system and the broader clinical ecosystem - including Oncology Information Systems (OIS), PACS servers, and other networked medical devices.
The ideal candidate brings deep hands-on experience with DICOM-RT standards, network-level system integration, and medical device software development under IEC 62304. You will play a key technical leadership role in defining and implementing the interoperability architecture that connects our treatment delivery system to the clinical workflow, working closely with partners, clinical customers, and internal cross-functional teams.
The position requires flexibility in daily tasks with attention to detail and a self-motivated work ethic. The successful candidate will have demonstrated experience working in cross-functional and cross-disciplinary teams and providing technical leadership in the development of novel products.
Key responsibilities:
  • Lead the design, specification, and implementation of DICOM-RT interoperability features, including RT Plan, RT Dose, RT Structure Set, RT Image, and RT Ion Plan objects.
  • Architect and develop network API interfaces enabling communication between the treatment delivery system, OIS (e.g. ARIA, Mosaiq), and PACS servers.
  • Define and maintain the system's DICOM Conformance Statement and related integration documentation.
  • Drive end-to-end integration testing with clinical systems, including HL7/FHIR messaging where applicable.
  • Perform as a technical lead on significant software development projects spanning interoperability and clinical connectivity.
  • Write specifications, requirements, design documents, and test protocols for software projects in accordance with IEC 62304 and the company design control process.
  • Develop safety-critical software for imaging and treatment delivery systems.
  • Work with external partners and clinical customers to develop, validate, and support system interfaces and integrations.
  • Contribute to the design and development of service and validation tools for DICOM interoperability.
  • Provide engineering support to partners, customers, and field service teams.
  • Support regulatory submissions (e.g. 510(k)) as they relate to interoperability and software.
  • Contribute to system architecture and software development process improvements.
  • Mentor less experienced engineers in interoperability standards and medical device software practices.
  • Manage contractors relating to software component development where applicable.

Relevant Knowledge and Skill requirements:
DICOM-RT and Clinical Interoperability
  • Deep working knowledge of DICOM-RT standards: RT Plan, RT Dose, RT Structure Set, RT Image, RT Ion Plan, and related SOP classes.
  • Practical experience integrating radiotherapy treatment systems with Oncology Information Systems (OIS) such as Varian ARIA or Elekta Mosaiq, and PACS servers.
  • Proficiency with DICOM networking protocols: C-STORE, C-FIND, C-MOVE, C-GET, DICOM TLS, Storage Commitment, and Worklist services.
  • Experience developing or maintaining a DICOM Conformance Statement.
  • Familiarity with HL7 v2 and/or FHIR messaging as used in oncology workflows is advantageous.
  • Understanding of IHE Radiation Oncology profiles (e.g. RO-PIR, IHE-RO) is a plus.

Medical Device Software Engineering
  • Proven experience developing medical device software in compliance with IEC 62304, including software lifecycle planning, classification, architecture, unit testing, and maintenance.
  • Familiarity with associated standards and guidance: ISO 14971 (risk management), IEC 62443 (cybersecurity), and applicable FDA/CE regulatory requirements for software.
  • Experience supporting regulatory submissions (510(k), CE Technical File) for software-intensive medical devices.
  • Experience with design and specification of software systems using UML.

Networking and Software Engineering
  • Solid understanding of TCP/IP networking: routing, firewalls, VLANs, TLS/SSL, and network security as it applies to connected medical devices.
  • Experience with REST and/or gRPC API design and integration in a clinical or embedded systems context.
  • Strong programming skills in Python and at least one of C++, C#, or Java.
  • Experience with Linux, shell scripting, and systems-level debugging.
  • Proficiency with version control (Git), CI/CD pipelines, and software testing frameworks.

Experience
  • Minimum 5 years of domain-specific experience in medical device software engineering within radiotherapy, radiation oncology, or a closely related imaging/treatment modality.
  • 10+ years of total software engineering experience, with demonstrated seniority in at least one prior role, is strongly preferred.
  • Experience working in cross-functional teams including clinical physics, systems engineering, quality, and regulatory affairs.
  • Ability to mentor and provide technical leadership to less experienced engineers.

About Leo Cancer Care
Leo Cancer Care is helping make changes in Radiation Therapy by shifting to upright patient positioning, imaging and treatment. We do what we do to find a better way, a better way to treat cancer and create a paradigm shift in radiation therapy to benefit all. We will do this by improving the accessibility and medicine in cancer care globally, making cancer treatment a more human experience for all.
Working in radiotherapy not only will you be driving change for the greater good, but you'll be working on products that span a large field of different disciplines.
Ways of Working
Leo Cancer Care is dedicated to fostering a diverse and inclusive workplace environment. We embrace and celebrate the unique backgrounds, experiences, and perspectives of all individuals. We believe that diversity enriches our organization and strengthens our ability to innovate and excel. Discrimination or harassment of any kind will not be tolerated. We encourage all qualified candidates to apply and join us in our mission to create a respectful and equitable workplace for all.
Leo Cancer Care is an equal opportunity employer.