Senior Evidence Synthesis Jobs (NOW HIRING)

AstraZeneca is a global, scienceled, patientfocused biopharmaceutical company that discovers, develops, and commercializes prescription medicines for some of the world's most serious diseases. We work in a fastpaced, agile environment powered by technology and digital innovation, united by a shared purpose to deliver lifechanging medicines. We are now seeking a Health Economics & Payer Evidence (HEPE) Director to join Global Market Access & Pricing (GMAP).

You will support our Respiratory & Immunology (R&I) portfolio, aligned with the Respiratory, Immunology & Other early Pipeline HEPE strategy. If you have deep knowledge in health economics, payer evidence requirements and their application to pharmaceutical development across international markets, this role offers the opportunity to influence development, strategy, and patient access at a global level. What you will do In this senior global leadership position, you will shape the strategic HEPE direction for the compounds under your responsibility.

Your work will focus on demonstrating the value of our products to patients, payers, and health authorities worldwide. By collaborating closely with Clinical Development, Medical Evidence Generation, Observational Research and Payer teams, you will design and implement innovative and insight-driven HEPE strategies that inform target product profiles, global payer evidence plans, and market access and pricing approaches. You will lead the generation of robust scientific evidence used to inform portfolio decisions, global reimbursement dossiers, and submissions to secure market access.

You will proactively identify and address challenges that may impact payer decisions and take responsibility for developing and executing detailed tactical and strategic payer evidence plans. Through creativity and scientific leadership, you will help build the strongest possible evidence packages to support patient access across diverse healthcare systems. You will prepare proposals for outsourced projects and work closely with local affiliates to ensure evidence packages reflect country-specific payer needs.

As the HEPE representative on cross-functional teams, you will ensure payer insights influence global development programs from early stages onward. As a leader, you will help develop the long-term capability of the HEPE R&I team, mentoring junior colleagues and contributing to the team's strategic direction. Essential requirements Experience in respiratory, immunology and earlypipeline activities, translating clinical plans into payer needs Demonstrated understanding of the development process for new molecules and the ability to align strategies with payer needs.

Knowledge of pricing and reimbursement processes across markets. Strong ability to interpret and analyse complex information and solve problems effectively. Strategic mindset with the ability to anticipate future challenges and develop breakthrough approaches.

Resilience and adaptability when navigating high-stakes or ambiguous situations. Experience driving publication strategies, developing peerreviewed research, and communicating complex ideas. Proven ability to build partnerships, work collaboratively, and address difficult issues with confidence.

Solid understanding of global healthcare systems and evolving payer evidence needs. Education, Training & Experience Degree in biomedical science, business, economics, or quantitative disciplines. Postgraduate training in health economics or equivalent experience.

Experience within payer, HTA, public health, or health policy. Minimum of three payer-related launches at any level (local, regional, or global). Deep technical capability in health economics, evidence synthesis, trial design/analysis, economic modelling, and other analytical methods relevant to payer needs.

If you're inspired by the prospect of shaping payer evidence and improving global patient access through strategic science, we would love to hear from you. The annual base pay for this position ranges from $218,361 - $327,542 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours.Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience

In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles),to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay(as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 26-May-2026 Closing Date 01-Jun-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.

If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.