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Senior Director Clinical Operations Jobs in Raleigh, NC

Role Overview The Senior Director, Sales - Large Pharma US, Clinical & Patient Technology is ... clinical execution, patient engagement, and operational transformation . Cross-Functional ...

Your focus will be on coordinating clinical operations delivery, resolving issues, and developing ... Minimum of 3 years of direct experience in biosample management is required * Proficiency in ...

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Senior Director Clinical Operations information

See Raleigh, NC salary details

$58.3K

$141.9K

$274.6K

How much do senior director clinical operations jobs pay per year?

As of Sep 8, 2026, the average yearly pay for senior director clinical operations in Raleigh, NC is $141,886.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,100.00 and $168,600.00 per year, depending on experience, location, and employer.

What is a senior director clinical operations?

A Senior Director of Clinical Operations oversees the planning, execution, and management of clinical trials to ensure compliance with regulatory guidelines and company objectives. They lead cross-functional teams, manage budgets, and develop strategies to optimize trial efficiency. This role requires strong leadership, strategic planning, and operational expertise to drive successful trial outcomes. They also collaborate with stakeholders, monitor trial progress, and implement process improvements.

What are the primary responsibilities of a senior director clinical operations?

A Senior Director Clinical Operations typically oversees multiple clinical trial programs, ensuring they run efficiently, meet quality and compliance standards, and stay within budget. They provide leadership and direction to clinical operations teams, collaborate closely with cross-functional departments like regulatory affairs, data management, and medical affairs, and engage with external vendors or partners as needed. Regular responsibilities also include monitoring project progress, addressing operational challenges, managing timelines, and developing process improvements. This role is highly collaborative and requires the ability to make strategic decisions that impact the success of trial outcomes and organizational goals.

What are the key skills and qualifications needed to thrive in the senior director clinical operations position?

To thrive as a Senior Director Clinical Operations, you need extensive experience in clinical research or healthcare management, a strong understanding of regulatory requirements (such as GCP and ICH), and typically hold an advanced degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), project management software, and regulatory submission tools is essential, and a certification such as PMP or ACRP can be advantageous. Outstanding leadership, strategic thinking, and communication skills help you effectively manage teams and build relationships with stakeholders. These competencies ensure operational excellence, compliant trial execution, and the ability to lead large, complex projects to successful outcomes.

What are popular job titles related to Senior Director Clinical Operations jobs in Raleigh, NC?

For Senior Director Clinical Operations jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Senior Director Clinical Operations jobs in Raleigh, NC look for?

The top searched job categories for Senior Director Clinical Operations jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Senior Director Clinical Operations jobs?

Cities near Raleigh, NC with the most Senior Director Clinical Operations job openings:

Infographic showing various Senior Director Clinical Operations job openings in Raleigh, NC as of September 2026, with employment types broken down into 1% As Needed, 78% Full Time, 18% Part Time, 2% Contract, and 1% Nights. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $141,886 per year, or $68.2 per hour.

Senior Director, Clinical Payments - Flex

Durham, NC โ€ข On-site

Worldwide Clinical Trials
Scientific Research and Development Servicesย โ€ขย 10K+ employees

Full-time

This job post hasย expired today.ย Applications are no longer accepted.


Job description

Who we are

We're a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world's most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs - in the best possible way.

Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.

Why Worldwide

We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day.Join us!

SUMMARY: The Senior Director, Clinical Payments - Flex is a full-time position responsible for the strategic leadership, market development, growth and operational oversight of Worldwide's Flex Payments business.

The Senior Director, Clinical Payments - Flex is responsible for development of commercial strategy, sponsor engagement, proposal support, operational readiness, service development and

global delivery capabilities for Flex Payments solutions.

RESPONSIBILITIES:

Tasks may include but are not limited to:

Responsibilities include leadership of the Flex Payments business including:

  • Develop and execute the strategic growth plan for Flex Payments.
  • Support Business Development, Proposals and Operational teams in the identification, development and conversion of Flex opportunities.
  • Act as the primary owner of all Flex opportunities from initial assessment through implementation and delivery readiness.
  • Collaborate with Sponsors, Business Development, Finance, Project Management and Operational teams to develop fit-for-purpose payment solutions.
  • Evaluate sponsor requirements and determine the most appropriate commercial and operational delivery model.
  • Develop pricing assumptions, budgets, resource plans and implementation strategies for new opportunities.
  • Ensure proposed solutions are operationally feasible, scalable and aligned with Worldwide capabilities.
  • Support proposal development, bid defences, sponsor meetings and commercial negotiations.
  • Develop and maintain Flex service offerings, operating models and supporting documentation.
  • Identify opportunities to expand Worldwide Clinical Trials service offerings through strategic payment solutions.
  • Drive continuous improvement of Flex processes, systems, service offerings and delivery models.
  • Develop and monitor pipeline metrics, conversion rates, implementation readiness and operational performance indicators.
  • Collaborate with Clinical Payments leadership to ensure alignment of Flex initiatives with broader departmental objectives.
  • Partner with Finance to support business cases, revenue forecasting, investment analysis and growth planning.
  • Establish implementation strategies for newly awarded opportunities and ensure successful transition into operational delivery.
  • Collaborate with Technology, Finance, Accounts Payable and Resource Management teams where required to support implementation and scalability.
  • Build, lead, coach and develop Flex Payments personnel as the organization grows.
  • Participate in client, sponsor and project team meetings as required.
  • Participate in all required applicable trainings.
  • Perform other duties as assigned. The duties and responsibilities listed above are representative of the nature and level of work assigned and are not necessarily all-inclusive.

OTHER SKILLS AND ABILITIES:

  • Exceptional leadership skills.
  • Strong commercial and business acumen.
  • Advanced knowledge of Clinical Payments operations and investigator payment processes.
  • Strong understanding of CRO proposal development, budgeting and sponsor contracting.
  • Excellent written and verbal communication skills.
  • Ability to influence and collaborate across multiple departments and levels of the organization.
  • Ability to work independently and as a team member.
  • Strong interpersonal skills in a fast-paced and rapidly changing environment.
  • Ability to exercise independent judgment with sensitivity to decisions requiring executive approval.
  • Strong analytical and problem-solving skills.
  • Ability to manage multiple priorities and competing deadlines.
  • Strong organizational skills.
  • Advanced skills in Microsoft Office applications including Excel, PowerPoint and Word.
  • Knowledge and understanding of ICH, GCP and FDA or EU directive regulations (as applicable) as well as local regulatory requirements.
  • Excellent spoken and written English skills.
  • Energetic, diligent and customer-oriented.

REQUIREMENTS:

  • At least 12 years' experience within CRO, Pharmaceutical, Biotechnology or related clinical research environments.
  • At least 5 years' experience in a leadership role.
  • Demonstrated experience in Clinical Payments, Finance, Operations, Business Development, Proposals or related functions.
  • Experience supporting sponsor-facing commercial activities and proposal development.
  • Experience leading global and cross-functional initiatives.
  • Four-year college curriculum or university degree OR
  • Skill sets and proven performance equivalent to above.
  • English, written and spoken, advanced level.

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.
The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):


United States of America - $140,500.00 - $278,500.00


The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.

We love knowing that someone is going to have a better life because of the work we do.

To view our other roles, check out our careers page at Discover a world of difference at Worldwide!For more information on Worldwide, visit www.Worldwide.com or connect with us on LinkedIn.