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Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com , and follow the company on LinkedIn , X , Facebook and YouTube . ( *in collaboration with AbbVie )

At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what's ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

About the Role:

The Senior Medical Director, Clinical Development will serve as a key medical and scientific leader responsible for defining and executing clinical development strategies for Neurocrine's obesity pipeline. This role provides independent medical leadership across Phase 1-3 clinical programs and partners closely with cross-functional teams including Clinical Operations, Clinical Project Management, Biometrics, Regulatory Affairs, Drug Safety, Translational Medicine, and Preclinical/Clinical Pharmacology.

As the Program/Therapeutic Medical Lead, the Senior Medical Director is accountable for the creation and execution of clinical development plans that support regulatory approval and advance Neurocrine's development portfolio. This role provides expert medical and strategic guidance to navigate complex scientific, clinical, and regulatory challenges, ensuring high-quality, compliant, and efficient development of novel therapies.

_Your Contributions (include, but are not limited to):Clinical Development Strategy & Leadership

• Develops and leads clinical development strategies for assigned obesity programs, with accountability for study design and medical integrity of clinical trials across Phase 1-3
• Serves as the Program/Therapeutic Medical Lead on cross-functional Program Teams, providing medical leadership and clinical input into integrated development plans
• Drives execution of the clinical development plan, ensuring alignment with corporate objectives, regulatory strategy, and scientific rationale
• Translates clinical strategy into actionable study designs and operational plans that deliver high-quality data and meaningful outcomes

Study Design, Execution & Oversight

• Leads preparation of clinical study synopses and is a major contributor to protocols, major amendments, and clinical study reports
• Oversees the design of data collection strategies and ensures appropriate interpretation and integration of clinical data
• Partners with Clinical Operations to oversee clinical trial execution in accordance with NBI SOPs, Good Clinical Practice (GCP), and applicable regulatory requirements
• Conducts medical assessment and disposition of adverse events in collaboration with Drug Safety, and provides ongoing evaluation of benefit-risk throughout clinical development

Cross-Functional & External Engagement

• Collaborates closely with internal stakeholders to support study activities requiring medical expertise
• Engages external experts, investigators, and key opinion leaders to inform strategy, optimize trial design, and advance programs
• Assists in identification and selection of clinical investigators and serves as Sponsor medical monitor/representative
• Works with Medical Affairs and external partners to communicate clinical data and establish new collaborations

Data Interpretation & Scientific Communication

• Leads analysis, interpretation, and presentation of clinical study results to internal and external audiences
• Provides strategic direction for scientific disclosures, including conference abstracts, presentations, and peer-reviewed publications
• Partners with Research and Translational Medicine to define biomarker strategies that enhance early clinical evaluation and decision-making

Portfolio & Organizational Leadership

• Interfaces with Research, Product Development, and Business Development to assess new product opportunities and shape clinical resear