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Senior Bioinformatics Software Engineer Jobs in Boston, MA

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. * Gets excited ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. * Gets excited ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. Gets excited ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. * Gets excited ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA · On-site

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. Gets excited ...

Vivo HealthStaff

Bioinformatics Scientist

Boston, MA

$170K - $190K/yr

Bioinformatics Scientist (Mid/Senior) Compensation: $170,000 - $190,000 Location: South San ... Is curious about the intersection of biology, algorithms, and software engineering. * Gets excited ...

Watershed Informatics

Software Engineer, UI

Boston, MA

$113K - $151K/yr

We have attracted some of the best bioinformatics, engineering, and commercial talent, and we are ... We are currently focused on mid-senior level, experienced engineers. To us, this means 2-7 years of ...

Apollo Solutions

Senior Software Engineer

Boston, MA · On-site

$133K - $175K/yr

Senior Software Engineer - Investment Team Location: Boston (Hybrid, 2 days per week in office) About the Role A leading global investment management firm is seeking a Senior Software Engineer to ...

BigTime Software

Senior Software Engineer

Boston, MA · On-site +1

$120K - $150K/yr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

BigTime Software

Senior Software Engineer

Boston, MA · On-site

$120K - $150K/yr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

BigTime Software

Senior Software Engineer

Boston, MA · On-site +1

$120K - $150K/yr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

BigTime Software

Senior Software Engineer

Boston, MA · On-site

$127.50 - $172.50/hr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

BigTime Software

Senior Software Engineer

Boston, MA · On-site +1

$120K - $150K/yr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

Bigtime Software Inc

Senior Software Engineer

Boston, MA · On-site

$135 - $165/hr

We are seeking an experienced Senior Software Engineer to join our team. In this role, you will work across the full application stack to design, develop, and test features in our cloud-based ...

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Showing results 21-40

All JobsBioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer Jobs in Boston, MA

Senior Bioinformatics Software Engineer information

See Boston, MA salary details

$91.8K

$111.1K

$129.8K

How much do senior bioinformatics software engineer jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior bioinformatics software engineer in Boston, MA is $111,107.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,700.00 and $119,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Boston, MA? The most popular types of Bioinformatics Software Engineer jobs in Boston, MA are:
What are popular job titles related to Senior Bioinformatics Software Engineer jobs in Boston, MA? For Senior Bioinformatics Software Engineer jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Senior Bioinformatics Software Engineer jobs in Boston, MA look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs in Boston, MA are:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 67% Full Time, and 33% Contract. Highlights an 67% In-person, and 33% Remote job distribution, with an average salary of $111,107 per year, or $53.4 per hour.

Bioinformatics Scientist

Vivo HealthStaff

Boston, MA

$170K - $190K/yr

Full-time

Re-posted 25 days ago

Job description

Bioinformatics Scientist (Mid/Senior)

Compensation: $170,000 - $190,000

Location: South San Francisco, CA

Job Type: Full-time (Hybrid)

Equity: Highly Competitive Equity

About Our Client

TechStaffers has partnered with one of our clients & they are on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Their sequencing services are used daily by thousands of innovators, including Nobel laureates, Fortune 100 pharma, and over 70,000 scientists. They began by revolutionizing plasmid sequencing, making it exponentially cheaper and faster. Now, they are expanding that same disruptive model across all of genomics, including a new RNA-seq service, to provide scientists everywhere with faster and more affordable access to data. Every team member plays a crucial role in driving the future of biotech research, building the world's most efficient sequencing engine that operates overnight and scales globally.

Position Overview

We are seeking a highly motivated mid- to senior-level Bioinformatics Scientist to work on the bioinformatics engine that powers this impact. This role is heavily bioinformatics-focused, emphasizing deep domain expertise and the building of scalable products over general software platform skills. You will wear many hats, leading projects from concept through production while maintaining strong ownership of your work.

Key Responsibilities

  • Build blazing-fast, production-grade bioinformatics workflows that process thousands of samples per day.
  • Develop novel algorithms that turn raw sequencing data into fast, intuitive, and accurate insights.
  • Hunt down bugs and tame the chaos of real-world sequencing data, including biological artifacts and platform quirks.
  • Translate bioinformatics outputs into a dynamic scientific UX that feels magical to researchers.
  • Stay on top of cutting-edge tools and find creative ways to integrate them into real-world pipelines.
  • Mentor teammates and grow your own skills in a fast-moving, collaborative environment.

Qualifications & Requirements

  • Education: PhD in Bioinformatics, Computer Science, Statistics, Biology, Biochemistry, Physics, or a closely related field.
  • Experience: 3+ years of experience developing production bioinformatics pipelines.
  • Industry Background: Minimum of 2 years of industry experience; candidates whose only experience is in academia will not be considered.
  • Domain Expertise: Strong background in microbial ecology or related fields, with a distinct preference for expertise in microbial genomics.
  • Technical Tools: Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required.
  • Sequencing Data: Hands-on work with Illumina or Oxford Nanopore sequencing platforms.
  • Product Impact: Proven experience building scalable bioinformatics products and clear evidence of delivering impactful, independent projects.
  • Bonus: Contribution of a novel bioinformatics tool or algorithm is highly regarded as a signal of a top-tier candidate.

Ideal Candidate Profile

  • Thrives with high agency and high ownership, leading projects from idea to production.
  • Exhibits strong leadership qualities, initiative, and a clear motivation to advance their career.
  • Is curious about the intersection of biology, algorithms, and software engineering.
  • Gets excited knowing their work directly accelerates the next generation of medicines and biotechnology.
  • Values clear communication and loves helping others level up.
  • Is energized by a tight-knit, fast-paced team environment.

Visa Requirements

  • Visa sponsorship is generally not available.
  • Able to accommodate TN or H-1B1
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About Vivo HealthStaff

Sourced by ZipRecruiter

Vivo HealthStaff provides permanent recruitment services for both clinical and administrative positions in the healthcare sector. Over the past 2 years, our clients have seen a 98% retention rate with Vivo HealthStaff placements.

Industry

Health care and social assistance

Company size

11 - 50 Employees

Headquarters location

Dublin, CA, US

Year founded

2016

Social media

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