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Science Program Manager Jobs in Missouri (NOW HIRING)

Principal, Technical Program Manager

O Fallon, MO · Hybrid

$120.70K - $156.20K/yr

Title and Summary Principal, Technical Program Manager Overview: The Artificial Intelligence ... Bachelor's degree in Computer Science, Software Engineering, Information Technology, or a related ...

Lead Technical Program Manager

O Fallon, MO · On-site

$120.70K - $156.20K/yr

Title and Summary Lead Technical Program Manager Who is Mastercard? Mastercard is a global ... Degree in Computer Science, Business or similar field • SAFe 4/5 certification is a plus ...

Lead Technical Program Manager

O Fallon, MO

$120.70K - $156.20K/yr

Title and Summary Lead Technical Program Manager Who is Mastercard? Mastercard is a global ... Science, Business or similar field SAFe 4/5 certification is a plus Mastercard is a merit-based ...

Lead Technical Program Manager

O Fallon, MO · On-site

$120.70K - $156.20K/yr

Title and Summary Lead Technical Program Manager Who is Mastercard? Mastercard is a global ... Degree in Computer Science, Business or similar field • SAFe 4/5 certification is a plus ...

Lead Technical Program Manager

O Fallon, MO

$120.70K - $156.20K/yr

Title and Summary Lead Technical Program Manager Who is Mastercard? Mastercard is a global ... Science, Business or similar field SAFe 4/5 certification is a plus Mastercard is a merit-based ...

The Program Manager will oversee roadmap definition, risk and budget management, stakeholder ... life sciences solutions. For nearly 40 years, we have combined exceptional people, deep domain ...

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Showing results 1-20

Science Program Manager information

What are the key skills and qualifications needed to thrive as a Science Program Manager, and why are they important?

To excel as a Science Program Manager, you need a strong background in scientific research or project management, typically supported by an advanced degree in a scientific field. Familiarity with project management tools (e.g., Microsoft Project, Asana) and certification such as PMP can be highly valuable. Excellent communication, leadership, and organizational skills are crucial for managing teams and coordinating across departments. These skills ensure effective alignment of scientific objectives, timely project delivery, and successful collaboration among stakeholders.

How does a Science Program Manager typically collaborate with researchers and cross-functional teams?

Science Program Managers play a crucial role in connecting researchers with other departments such as engineering, product development, and regulatory affairs. They coordinate project timelines, facilitate communication among stakeholders, and help resolve scientific or logistical challenges that arise during research initiatives. Regular meetings, status updates, and collaborative planning sessions are typical, allowing the Program Manager to ensure that projects remain aligned with broader organizational goals while supporting the innovative work of research teams.

What does a Science Program Manager do?

A Science Program Manager oversees the planning, coordination, and execution of scientific projects and programs. They work closely with research teams, stakeholders, and funding agencies to ensure that projects meet their objectives, stay within budget, and adhere to timelines. Their responsibilities often include grant management, facilitating communication between different departments, and ensuring compliance with regulatory standards. Science Program Managers play a key role in translating scientific goals into actionable plans and helping organizations achieve their research and development objectives.

What is the difference between Science Program Manager vs Research Scientist?

AspectScience Program ManagerResearch Scientist
CredentialsBachelor's or Master's in Science, project management certifications often preferredAdvanced degree (Master's or PhD) in a scientific field
Work EnvironmentProject coordination, cross-functional teams, administrative tasksLaboratory research, data analysis, experimental work
Employer & IndustryResearch institutions, biotech, pharma, government agenciesUniversities, research labs, industry R&D
Search & Comparison IntentUnderstanding project management roles in scienceScientific research and experimental work

The main difference is that a Science Program Manager oversees scientific projects, coordinating teams and resources, while a Research Scientist conducts experiments and generates scientific data. Both roles require strong scientific credentials, but their daily tasks and focus differ significantly.

What cities in Missouri are hiring for Science Program Manager jobs? Cities in Missouri with the most Science Program Manager job openings:
Infographic showing various Science Program Manager job openings in Missouri as of May 2026, with employment types broken down into 1% As Needed, 84% Full Time, 12% Part Time, and 3% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution.
Senior Technical Program Manager

Senior Technical Program Manager

Mastercard, Inc.

O Fallon, MO • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 16 days ago


Job description

Our Purpose
Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we're helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.
Title and Summary
Senior Technical Program Manager
OVERVIEW
Are you a technical program manager who wants to work for a company that offers above and beyond benefits including paid parental leave, flexible work hours, gift matching, and even volunteer incentives? Do you want to work in an inclusive and nurturing culture that encourages your own professional learning and development?
At Mastercard, our industry expertise is enhanced by our commitment to being a force for good in the world. We do well by doing good. Our core values of trust, partnership, agility and thoughtful risk taking are displayed in everything we do. Our culture of collaboration and inclusion makes our company the place where the best people choose to be. Come join us!
The Payment Resiliency program consists of globally scalable products focused on bettering the safety intelligence and resiliency of the Mastercard Authorization network. To fully integrate security and intelligence into the transaction process, the team works to develop merchant and consumer services, improve transaction validation services, and integrate security services with digital payments products.
ROLE
We are looking for experienced technical program management professionals to join our team and help us build towards the future. Our Technical Program Managers (TPM) conceptualize, rationalize, and drive multiple simultaneous projects to deliver engineering work across the portfolio in our scrum execution model. In this role, you get to dive as deep as you want into the tech stack, the integration patterns, the organizational capabilities, and the company wide assets that can be leveraged to provide technical solutions to customer problems. You will contribute to the strategies, design choices, and even the cloud infrastructure necessary to build comprehensive believable and achievable execution plans to deliver high-profile new features and capabilities for our customers. You may drive the execution of a feature through the full stack or may drive a project which spans multiple teams and integrations, reporting meaningful status along the way.
ALL ABOUT YOU
• Demonstrated ability to operate with independence and autonomy
• Deep understanding of Software Development Methodologies and Lifecycles
• Understanding of cloud-native software products, platforms capabilities and underlying technologies.
• Enjoys diving deep to understand of the platform capabilities and underlying technologies.
• Demonstrated experience breaking down problems, organizing work, planning sprints, and delivering technical programs in agile delivery models (scrum, Kanban, etc.)
• Fluent in reporting mechanisms such as power-points, JIRA, burn up/down charts and other team performance and productivity metrics reporting methods
• Proven track record of data driven decision-making and applying continuous improvement methodologies across teams
• Can debate the delivery strategy with business teams, architects, engineers, and designers
• Can communicate to executives, peers, and staff with impact, eloquence, and authenticity
• Demonstrated experience building relationships, partnering with and influencing dependent teams while commanding the respect of the individuals you work with across the organization
• Huge plus if you have expertise in Payments, IaaS, PaaS, serverless technology, CI/CD, NoSQL databases, microservices APIs, and distributed systems operations in a DevOps model
• Technical program delivery experience including time analyzing, developing, or testing software
• Ability to understand technical products, how they work, dependencies and their support aspects including Release Management.
• BS in engineering, computer science or related discipline.
Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.
Corporate Security Responsibility
All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:
  • Abide by Mastercard's security policies and practices;
  • Ensure the confidentiality and integrity of the information being accessed;
  • Report any suspected information security violation or breach, and
  • Complete all periodic mandatory security trainings in accordance with Mastercard's guidelines.

In line with Mastercard's total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations.
Pay Ranges
O'Fallon, Missouri: $96,000 - $163,000 USD