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Remote Software Engineer 300K Jobs in Indiana (NOW HIRING)

micro1 AI

Bioinformatics Software Engineer

South Bend, IN · Remote

$80 - $110/hr

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

micro1 AI

Bioinformatics Software Engineer

Fort Wayne, IN · Remote

$80 - $110/hr

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

Circle

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Florence, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Boston, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Miami, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Atlanta, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Portland, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Columbus, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Nashville, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

Manager, Software Engineering

Austin, IN · On-site +1

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Circle

$195K - $257K/yr

Lead agile software processes for engineering teams and introduce best-in-class industry practices ... You have experience managing remote teams * The ability to thrive on a fast pace environment with ...

Harris

In this role, you will directly contribute to that mission by ensuring our software provides a ... This remote role welcomes candidates anywhere in Canada and the US. Travel is required as needed ...

Harris

In this role, you will directly contribute to that mission by ensuring our software provides a ... This remote role welcomes candidates anywhere in Canada and the US. Travel is required as needed ...

K1X

Data Engineer

Indianapolis, IN · On-site +1

$109K - $131K/yr

... software. k1x.io As our platform evolves toward deeper analytics, insights, and AI-driven ... Fully Remote Opportunity * Healthcare Benefits and 401K * Growing Startup Culture

K1X

Data Engineer

Indianapolis, IN · On-site +1

$109K - $131K/yr

... software. k1x.io As our platform evolves toward deeper analytics, insights, and AI-driven ... Fully Remote Opportunity * Healthcare Benefits and 401K * Growing Startup Culture

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Remote Software Engineer 300K information

What is a remote software engineer?

A Remote Software Engineer is a professional who designs, develops, and maintains software applications while working from a location outside of a traditional office environment. Earning a $300K salary as a remote software engineer typically requires advanced technical expertise, experience with in-demand programming languages, and a proven track record in high-impact roles or specialized industries such as finance, big tech, or startups. These positions often involve complex systems architecture, leadership responsibilities, or niche skills, and can be found at leading technology companies or through high-paying contract work. Negotiating competitive compensation, contributing to open-source projects, and continuously updating skills are also important factors in achieving this salary level.

What are the key skills and qualifications needed to thrive as a remote software engineer earning $300K?

To thrive as a Remote Software Engineer at a high compensation level, you need advanced programming skills, deep knowledge of software architecture, and a degree in computer science or equivalent experience. Mastery of languages like Python, Java, or C++, along with expertise in cloud platforms, CI/CD systems, and relevant certifications (such as AWS Certified Solutions Architect), are often required. Exceptional problem-solving, self-motivation, and strong communication skills help you excel in distributed, collaborative environments. These capabilities ensure you can deliver complex solutions independently, drive team success, and make significant contributions that justify top-tier compensation.

What are some common challenges faced by remote software engineers in high-paying roles, and how can they be addressed?

Remote software engineers, especially in high-paying positions, often encounter challenges such as time zone differences, maintaining clear communication with distributed teams, and ensuring productivity without in-person supervision. To address these, it's important to leverage collaboration tools, set clear expectations with team members, and proactively communicate progress and blockers. Regular virtual meetings and structured daily routines can also help maintain alignment and foster a sense of connection within the team.

What is the difference between Remote Software Engineer 300K vs Remote Developer 300K?

AspectRemote Software Engineer 300KRemote Developer 300K
Required CredentialsBachelor's in CS or related field, coding skillsBachelor's in CS or related field, coding skills
Work EnvironmentRemote, collaborative teams, Agile workflowsRemote, project-based, Agile or Scrum teams
Industry UsageTech, finance, startups, enterpriseTech, SaaS, startups, consulting
Common Search IntentHigh-level engineering roles, salary expectationsDevelopment roles, salary comparison

Both Remote Software Engineer 300K and Remote Developer 300K roles require similar technical credentials and often operate in remote, collaborative environments across various industries. The main difference lies in job focus: software engineers typically work on system architecture and complex coding, while developers may focus more on application development. Candidates should choose based on their specific skills and career goals.

What are the most commonly searched types of Software Engineer 300K jobs in Indiana?

The most popular types of Software Engineer 300K jobs in Indiana are:

What are popular job titles related to Remote Software Engineer 300K jobs in Indiana?

For Remote Software Engineer 300K jobs in Indiana, the most frequently searched job titles are:

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The top searched job categories for Remote Software Engineer 300K jobs in Indiana are:

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Cities in Indiana with the most Remote Software Engineer 300K job openings:

Remote Software Engineer 300K jobs near you

Bioinformatics Software Engineer

micro1 AI

South Bend, IN • Remote

$80 - $110/hr

Part-time

Posted 16 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

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