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Remote Mathematical Modeling Jobs (NOW HIRING)

Vrtx

HEOR Modeling Director (Remote-Eligible)

Boston, MA · On-site +1

$204K - $306K/yr

... to economic models. The role has flexibility to be in-person, hybrid, or remote. Key ... Advanced degree in health economics or a related discipline (such as mathematics, statistics ...

ARRISE

Math Tools Engineer

With a remote team of product experts, we're tapping into American talent to drive the next ... models * Excellent verbal and written communication skills, especially the ability to clearly ...

ARRISE

Math Tools Engineer

With a remote team of product experts, we're tapping into American talent to drive the next ... models * Excellent verbal and written communication skills, especially the ability to clearly ...

Mercor

STEM Expert - Fully Remote

New York, NY · Remote

$70 - $100/hr

... Mathematics , Statistics , Computer Science , Electrical Engineering , Mechanical Engineering ... Demonstrated technical expertise in at least one domain: computational modeling, laboratory methods ...

Experian

Senior Data Modeling Analyst - Remote

Costa Mesa, CA · On-site +1

$92K - $116K/yr

Bachelor's degree in Computer Science, Data Science, Mathematics, Statistics, or a related ... Knowledge of statistical models and practical experience in predictive model development (Python, R ...

SAIC

Launch Cost Estimator Analyst

El Segundo, CA · On-site +1

$160K - $200K/yr

None Potential for Remote Work: ORA_ON_SITE Description SAIC has an opening for a Launch Cost ... mathematical modeling and other optimizing methods to develop and interpret information that ...

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How much do remote mathematical modeling jobs pay per year?

As of Jul 12, 2026, the average yearly pay for remote mathematical modeling in the United States is $127,031.00, according to ZipRecruiter salary data. Most workers in this role earn between $109,000.00 and $143,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by remote mathematical modelers, and how can they be addressed?

Remote mathematical modelers often encounter challenges such as limited real-time collaboration with colleagues, potential miscommunication regarding model requirements, and managing complex data sets independently. These can be addressed by utilizing collaborative tools like shared code repositories, regular virtual meetings, and clear documentation practices. Additionally, proactively seeking feedback and maintaining open channels of communication with stakeholders can help ensure alignment and successful project outcomes.

What is remote mathematical modeling?

Remote mathematical modeling involves using mathematical equations and computational methods to represent real-world systems or processes, all while working from a location outside of a traditional office environment. Professionals in this field use tools like MATLAB, Python, or R to develop and analyze models for industries such as finance, engineering, healthcare, and environmental science. The remote aspect allows for flexible collaboration with teams worldwide through digital communication platforms. This role typically requires strong analytical skills, problem-solving abilities, and proficiency in mathematical software.

What are the key skills and qualifications needed to thrive as a Remote Mathematical Modeler, and why are they important?

To thrive as a Remote Mathematical Modeler, you need a strong background in mathematics, statistics, and computational modeling, typically supported by a relevant degree such as mathematics, engineering, or physics. Proficiency with technical tools like MATLAB, R, Python, and specialized modeling software, as well as experience with data analysis and simulation platforms, is essential. Strong problem-solving, analytical thinking, and effective written communication skills set top performers apart in this role. These skills are crucial for developing accurate models, interpreting complex data remotely, and delivering clear insights to clients or stakeholders.
More about Remote Mathematical Modeling jobs
What cities are hiring for Remote Mathematical Modeling jobs? Cities with the most Remote Mathematical Modeling job openings:
What are the most commonly searched types of Mathematical Modeling jobs? The most popular types of Mathematical Modeling jobs are:
What states have the most Remote Mathematical Modeling jobs? States with the most job openings for Remote Mathematical Modeling jobs include:
What job categories do people searching Remote Mathematical Modeling jobs look for? The top searched job categories for Remote Mathematical Modeling jobs are:
Remote Mathematical Modeling jobs near you
Infographic showing various Remote Mathematical Modeling job openings in the United States as of July 2026, with employment types broken down into 5% Internship, 70% Full Time, 15% Part Time, 5% Temporary, and 5% Contract. Highlights an 100% Remote job distribution, with an average salary of $127,031 per year, or $61.1 per hour.
HEOR Modeling Director (Remote-Eligible)

HEOR Modeling Director (Remote-Eligible)

Vertex Pharmaceuticals

Boston, MA • On-site, Remote

$204K - $306K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 24 days ago

Job description

Job Description
Job Summary:
Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Director within the Modeling Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical modeling support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Director will be to lead the team that supports the HEOR disease/asset teams in developing health economic models, including models that will provide the foundations for HTA submissions, as well as early models to inform evidence generation needs. The Director will set the direction for modeling strategy across one or more therapeutic areas or pipeline assets. The Director will provide input into global product value strategy and tactics as well as input to design and interpretation of post-hoc clinical trial analyses and evidence generation studies that relate to economic models. The role has flexibility to be in-person, hybrid, or remote.
Key Responsibilities:
  • Set the direction for modeling strategy across one or more therapeutic areas or pipeline assets
  • Provide leadership and support to the HEOR Modeling team as they develop and roll out economic models to support product value strategy
  • Lead the development of global cost-effectiveness and budget impact models, and associated materials. The work may involve both in-house "hands-on" development of models (de novo programming) as well as management and quality assurance and validation of work conducted by external vendors
  • Conduct model trainings and provide support to regional teams in local adaptation process and development of HTA submissions, as well as continued support during negotiations with reimbursement authorities
  • Provide thought leadership on economic modeling to support development of strategic plans and evidence generation activities
  • Provide input into design and interpretation of evidence generation studies needed to support economic models
  • Provide subject matter expertise/knowledge to cross-functional partners to support understanding and appropriate application of relevant HEOR evidence in support of access/reimbursement
  • Present research findings at scientific congresses, participate in development of high-quality publications for peer-review

Minimum Qualifications:
  • Advanced degree in health economics or a related discipline (such as mathematics, statistics, economics, epidemiology)
  • Typically requires 10 years of relevant experience in health economics and outcomes research, or the equivalent combination of education and experience
  • Preference for previous supervisory/management experience
  • Extensive experience designing and developing health economic models; preferred experience in modeling work to support HTA submissions and negotiations
  • Excellent communication skills, strong oral/written presentation skills
  • Ability to manage complexity and ambiguity in a highly matrixed work environment
  • Ability to navigate and be successful in a fast-paced environment

Pay Range:
$204,000 - $306,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-Eligible
Flex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Remote
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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