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Remote Infrastructure Software Engineer Jobs in Cleveland, OH

micro1 AI

Bioinformatics Software Engineer

Cleveland, OH · Remote

$80 - $110/hr

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

micro1 AI

Bioinformatics Software Engineer

Akron, OH · Remote

$80 - $110/hr

Remote micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer's computational drug discovery project. In this role, you'll apply your expertise ...

Greenfield Talent

Data Engineer (Remote)

Cleveland, OH · Remote

$111K - $133K/yr

We're looking for a Data Engineer to join our Data & Analytics team and take ownership of the data infrastructure that powers internal analytics, reporting, and operational insights. This is a ...

Nexus Engineering Group

Substation Engineer

Cleveland, OH · On-site +1

$75K - $85K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... infrastructure projects while delivering high-quality engineering. Why Nexus You'll own a piece of ... Familiarity with engineering software such as AutoCAD, MicroStation, ETAP, SKM, CYME, CDEGS ...

Nexus Engineering Group

Substation Engineer

Cleveland, OH · On-site +1

$75K - $85K/yr

... infrastructure projects while delivering high-quality engineering. Why Nexus You'll own a piece of ... Familiarity with engineering software such as AutoCAD, MicroStation, ETAP, SKM, CYME, CDEGS ...

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Remote Infrastructure Software Engineer information

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$112K

$174.8K

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How much do remote infrastructure software engineer jobs pay per year?

As of Aug 13, 2026, the average yearly pay for remote infrastructure software engineer in Cleveland, OH is $174,827.00, according to ZipRecruiter salary data. Most workers in this role earn between $167,800.00 and $198,800.00 per year, depending on experience, location, and employer.

What is a remote infrastructure software engineer?

Remote Infrastructure Software Engineers are professionals who design, build, and maintain the core systems and services that support an organization's IT infrastructure, all while working remotely. They focus on ensuring that networks, servers, cloud environments, and related software are secure, scalable, and reliable. Their responsibilities may include automating deployment processes, managing cloud resources, monitoring system performance, and troubleshooting issues. By working remotely, they leverage various collaboration tools to communicate with teams and manage critical infrastructure from anywhere.

How does a remote infrastructure software engineer typically collaborate with cross-functional teams in a distributed work environment?

Remote Infrastructure Software Engineers regularly work with DevOps, security, and development teams to ensure that infrastructure solutions are reliable and scalable. Collaboration often happens through daily stand-ups, code reviews, and shared documentation platforms, making strong communication skills essential. Tools like Slack, Jira, and Zoom are commonly used to bridge the distance and keep projects aligned. Successfully navigating time zone differences and asynchronous communication is a key part of the role, requiring proactive updates and flexibility.

What are the key skills and qualifications needed to thrive as a remote infrastructure software engineer, and why are they important?

To thrive as a Remote Infrastructure Software Engineer, you need a strong background in software engineering, computer networking, and distributed systems, typically supported by a degree in computer science or a related field. Familiarity with cloud platforms (such as AWS, Azure, or GCP), infrastructure-as-code tools (like Terraform or Ansible), and CI/CD systems is essential, along with relevant certifications like AWS Certified Solutions Architect. Excellent problem-solving, communication, and self-management skills are crucial for collaborating effectively across distributed teams and handling complex remote projects. These skills ensure secure, reliable, and scalable systems that support business goals in a remote work environment.

What are the most commonly searched types of Infrastructure Software Engineer jobs in Cleveland, OH?

The most popular types of Infrastructure Software Engineer jobs in Cleveland, OH are:

What are popular job titles related to Remote Infrastructure Software Engineer jobs in Cleveland, OH?

For Remote Infrastructure Software Engineer jobs in Cleveland, OH, the most frequently searched job titles are:

What job categories do people searching Remote Infrastructure Software Engineer jobs in Cleveland, OH look for?

The top searched job categories for Remote Infrastructure Software Engineer jobs in Cleveland, OH are:

What cities near Cleveland, OH are hiring for Remote Infrastructure Software Engineer jobs?

Cities near Cleveland, OH with the most Remote Infrastructure Software Engineer job openings:

Remote Infrastructure Software Engineer jobs near you

Bioinformatics Software Engineer

micro1 AI

Cleveland, OH • Remote

$80 - $110/hr

Part-time

Posted 10 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

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