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Real World Evidence Jobs (NOW HIRING)

TechData Service Company LLC

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Remote Statistician-Real World Evidence (RWE)

King Of Prussia, PA · Remote

$100K - $160K/yr

The RWE Statistician is involved in planning, conducting and analyzing real-world evidence studies (prospective & retrospective observational study, electronic medical records, claim database ...

Alzheon, Inc.

Head of Real-World Evidence

Framingham, MA · On-site

$180 - $240/hr

Position Overview Alzheon is seeking a Head of Real-World Evidence to build and lead the company's RWE function. This individual will define the evidence strategy that complements our clinical ...

Alzheon, Inc.

$180 - $240/hr

Position Overview Alzheon is seeking a Head of Real-World Evidence to build and lead the company's RWE function. This individual will define the evidence strategy that complements our clinical ...

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How much do real world evidence jobs pay per year?

As of Sep 7, 2026, the average yearly pay for real world evidence in the United States is $43,297.00, according to ZipRecruiter salary data. Most workers in this role earn between $36,000.00 and $48,000.00 per year, depending on experience, location, and employer.

What is a real world evidence?

A Real World Evidence (RWE) job involves analyzing data from real-world sources, such as electronic health records, claims databases, and patient registries, to generate insights on the safety, effectiveness, and value of medical treatments. Professionals in this field work with biopharmaceutical companies, healthcare organizations, and regulatory agencies to support clinical decision-making, policy development, and market access strategies. Roles often require expertise in epidemiology, biostatistics, and data analytics, along with knowledge of healthcare systems and regulatory frameworks.

What are the typical responsibilities of someone working in a real world evidence role?

Professionals in Real World Evidence (RWE) roles are responsible for designing, executing, and analyzing studies using real-world health data to generate insights that inform medical, regulatory, and market access decisions. Their day-to-day tasks often include data management, statistical analysis, collaborating with cross-functional teams (such as clinical, regulatory, and medical affairs), and communicating findings through reports or presentations. They may also be involved in developing protocols, working with external partners or data vendors, and ensuring research complies with ethical and regulatory standards. This dynamic role requires balancing analytical work with collaboration and communication across multiple stakeholders.

What are the key skills and qualifications needed to thrive in the real world evidence position, and why are they important?

To thrive in Real World Evidence roles, you need a strong background in epidemiology, biostatistics, and data analysis, typically supported by an advanced degree in a relevant scientific or health field. Familiarity with data analytics tools (such as SAS, R, or SQL), real-world data sources (like electronic health records and claims databases), and knowledge of regulatory guidelines are highly valued. Exceptional communication, critical thinking, and problem-solving abilities help in translating complex data into actionable health insights and working effectively with diverse teams. These competencies are crucial for generating, interpreting, and delivering real-world evidence that informs healthcare decision-making and supports regulatory submissions.

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Real World Evidence jobs near you
Infographic showing various Real World Evidence job openings in the United States as of August 2026, with employment types broken down into 78% Full Time, 18% Part Time, 3% Contract, and 1% Nights. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $43,297 per year, or $20.8 per hour.

Manager, Insight Outcomes & Real-World Evidence

Alphatec Spine

Carlsbad, CA • On-site

Full-time

Posted 5 days ago

Job description

The Manager, Insight Outcomes and Real-World Evidence will help build and execute the clinical outcomes, registry, and evidence-generation strategy for ATEC's Insight platform. This role is responsible for translating Insight's clinical and business objectives into practical study plans, patient-reported outcomes workflows, investigator engagement, evidence outputs, and cross-functional execution that support clinical adoption, reimbursement strategy, payer-facing evidence, regulatory needs, and commercial differentiation.
This position is intended for a hands-on clinical evidence leader who can operate across Scientific Affairs, Regulatory, Marketing, Commercial Teams, and external clinical sites. The role will focus on building an outcomes infrastructure that supports Insight as a clinical intelligence and value-generation platform, not simply a software tool.
Essential Duties and Responsibilities
  • Lead the development and execution of the Insight evidence strategy, aligning real-world evidence, outcomes research, and value evidence with product innovation, clinical adoption, reimbursement, publication, and commercial objectives.
  • Identify evidence gaps and define research priorities that demonstrate the clinical, operational, and economic value of Insight-enabled spine care.
  • Partner with Marketing, Scientific Affairs, Regulatory Affairs, and Commercial teams to ensure evidence generation supports strategic business priorities and future product claims.
  • Oversee the development and adoption of the real-world evidence platform by integrating clinical registries with patient-reported outcomes, imaging, EHRs, activity monitoring, healthcare claims, coding databases, and other relevant data sources.
  • Establish scalable processes for data collection, quality, governance, and longitudinal outcomes tracking to support clinical research, benchmarking, and advanced analytics.
  • Develop evidence assets that enable providers, hospitals, and payers to evaluate clinical performance, operational efficiency, patient recovery, and economic value.
  • Design and oversee observational studies, registry analyses, and outcomes research that generate evidence supporting clinical utility, healthcare economics, reimbursement, and value-based care.
  • Independently drive collaboration with internal and external research partners to translate real-world data into actionable insights, predictive analytics, publications, and scientific presentations.
  • Support the development of value dossiers, reimbursement evidence, and health economic analyses for providers, health systems, and payers.
  • Build and maintain collaborative relationships with investigators, clinical sites, academic partners, and professional societies to expand Insight evidence generation and scientific engagement.
  • Support investigator-initiated research and multicenter collaborations that strengthen the clinical and economic evidence supporting Insight technologies.

SUPERVISORY RESPONSIBILITIES
This role may not initially have direct reports. The position requires strong cross-functional influence and day-to-day coordination of internal contributors, clinical sites, investigators, vendors, and external partners. Direct people management responsibilities may be added as the Insight evidence program scales.
Requirements
The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
  • Bachelor's degree in life sciences, clinical research, biotechnology, epidemiology, public health, health economics, healthcare administration, or related field required. Advanced degree preferred.
  • Minimum 6 to 8 years of progressive experience in real-world evidence, clinical registries, health economics and outcomes research, healthcare analytics in digital health, medical imaging, spine/orthopedic or related fields.
  • Experience developing and managing clinical registries and integrating diverse healthcare data sources, including EHRs, imaging, patient-reported outcomes, claims, administrative coding, and digital health or wearable data. Knowledge of interoperability standards is a plus.
  • Demonstrated experience with observational study design, real-world evidence methodologies, comparative effectiveness research, and healthcare economics.
  • Familiarity with patient-reported outcomes instruments commonly used in spine and orthopedics, including pain, function, quality of life, or recovery assessment preferred.
  • Awareness of reimbursement, payer evidence, health economics, value-based care, alternative payment models, coding strategy, claims data, and hospital performance metrics preferred.
  • Understanding of how clinical evidence supports product claims, regulatory submissions, market access, physician adoption, and scientific credibility.
  • Knowledge, understanding, and application of the conduct of clinical investigations involving humans in accordance ICH/GCP, US Code of Federal Regulations (CFR), and the ethical principles that guide clinical research consistent with the principles of the Nuremberg Code, the Belmont Report and the Declaration of Helsinki.
  • Strategic and analytical mindset with the ability to translate complex evidence needs into actionable research plans and meaningful clinical, operational, economic, and reimbursement insights.
  • Strong communication and collaboration skills, capable of influencing cross-functional teams, building trusted relationships with internal and external stakeholders, and communicating complex information to technical and executive audiences.
  • Results-oriented project leadership, demonstrating sound judgment, accountability, and the ability to manage multiple priorities while thriving in a dynamic, fast-paced environment.
  • Commitment to scientific integrity and quality, maintaining high standards for clinical evidence, data credibility, patient privacy, and ethical research practices while balancing scientific rigor with business objectives.
  • Collaborative, curious, and solutions-focused, with strong attention to detail, a proactive approach to problem-solving, and the ability to turn ambiguity into organized execution.

Education and Experience
  • Bachelor's degree in life sciences, clinical research, biotechnology, public health, healthcare administration, health economics, epidemiology, or related field.
  • Preferred - Master's degree in biotechnology, clinical research, public health, health economics, epidemiology, healthcare administration, or related field.
  • 6 to 9 years progressive experience in clinical research, clinical operations, evidence generation, outcomes research, registry execution, or related healthcare/medical technology environment.
  • Preferred - ACRP, SOCRA, CCRC, CCRP, GCP, human subjects protection, or equivalent clinical research certification.

Equal Employment Opportunity & Other Disclosures
ATEC is committed to providing equal employment opportunities to its employees and applicants without regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, gender expression, or any other protected status in accordance with all applicable federal, state or local laws. Further, ATEC will make reasonable accommodations that are necessary to comply with disability discrimination laws.
For roles based in the United States that require access to hospital facilities, must be eligible for and maintain credentials at all required hospitals, including meeting any applicable physical requirements or vaccination requirements (including the COVID-19 vaccine, as applicable).
At this time, ATEC Spine does not sponsor employment visas for this position. Candidates must be authorized to work in the United States without the need for current or future employer sponsorship.
Salary Range
Alphatec Spine, Inc. complies with state and federal wage and hour laws and compensation depends upon candidate's qualifications, education, skill set, years of experience, and internal equity. $145,000-$190,000 Full-Time annual salary

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