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Director Real World Evidence Jobs (NOW HIRING)

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We are seeking a Principal Clinical Scientist / Associate Director of Real-World Evidence & Epidemiology to drive observational evidence strategy for our Early Cancer Detection (ECD) portfolio.

Associate Director, Real-World Evidence & Epidemiology

$176K - $220K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

We are seeking a Principal Clinical Scientist / Associate Director of Real-World Evidence & Epidemiology to drive observational evidence strategy for our Early Cancer Detection (ECD) portfolio.

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How much do director real world evidence jobs pay per year?

As of Aug 13, 2026, the average yearly pay for director real world evidence in the United States is $123,955.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $137,000.00 per year, depending on experience, location, and employer.

What is the difference between Director Real World Evidence vs Clinical Data Manager?

AspectDirector Real World EvidenceClinical Data Manager
Required CredentialsAdvanced degree (PhD, MD, or Master’s), experience in RWE, biostatisticsBachelor’s or Master’s in life sciences, clinical research, or related field
Work EnvironmentStrategic, cross-functional teams, focus on observational studiesData collection, database management, clinical trial support
Employer & Industry UsagePharmaceutical, biotech companies, healthcare analyticsClinical research organizations, hospitals, pharma companies
Common Search & Comparison IntentUnderstanding senior roles in RWEOperational data management roles in clinical trials

The main difference is that the Director of Real World Evidence focuses on strategic analysis of observational data to inform healthcare decisions, while a Clinical Data Manager handles the operational aspects of managing clinical trial data. Both roles require strong scientific backgrounds but differ in scope and responsibilities.

What is a director of real world evidence?

A Director of Real World Evidence (RWE) is a senior professional in the healthcare or pharmaceutical industry responsible for overseeing the collection and analysis of real-world data to generate insights about the use, safety, and effectiveness of medical products. They lead teams that design and implement studies using data from sources like electronic health records, insurance claims, and patient registries. Their work helps inform regulatory decisions, support product development, and improve patient outcomes. The role requires expertise in epidemiology, data science, and regulatory requirements, as well as strong leadership and communication skills.

What are the key skills and qualifications needed to thrive as a director of real world evidence, and why are they important?

To thrive as a Director of Real World Evidence, you need advanced expertise in epidemiology, biostatistics, and data analytics, typically supported by a graduate degree in a related field and significant experience in pharmaceutical or healthcare research. Mastery of statistical software (such as SAS, R, or Python), familiarity with real-world data sources (like claims or EMR databases), and knowledge of regulatory guidelines are crucial. Exceptional leadership, communication, and stakeholder management skills distinguish top performers in this role. These competencies ensure robust evidence generation, effective cross-functional collaboration, and impactful decision-making that drives value for healthcare organizations.

How does a director of real world evidence collaborate with cross-functional teams to drive evidence generation projects?

A Director of Real World Evidence (RWE) works closely with clinical, regulatory, medical affairs, biostatistics, and data science teams to design and execute studies that generate actionable insights from real-world data. This role often involves leading project teams, aligning stakeholder objectives, and ensuring that RWE strategies support both product development and post-market decision-making. Effective communication and project management skills are essential, as the Director must synthesize input from diverse experts, manage timelines, and ensure that evidence generation aligns with regulatory and business goals.
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Infographic showing various Director Real World Evidence job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 77% Full Time, 18% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $123,955 per year, or $59.6 per hour.

Assoc Director, Real-World Evidence

Gilead Sciences, Inc.

Foster City, CA • On-site

Full-time

Medical, Dental, Vision, Life, PTO

Re-posted 24 days ago


Gilead Sciences rating

8.9

Company rating: 8.9 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

9th of 86 rated pharmaceutical


Job description

We're here for one reason and one reason only - to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We've made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
We are seeking an Associate Director, Real-World Evidence (RWE), who will lead real-world evidence generation across the product lifecycle, with a core focus on execution of external control arms (ECAs) and other complex observational studies. This role is central to Kite's ability to contextualize single-arm trials and evolving treatment landscapes, support access, and strengthen evidence packages for innovative cell therapies. You will also serve as a leader of RWE in scientific forums, and collaborate with external physicians, scientists, and researchers, as well as alliance partners, on RWE activities.
This role can be office-based in our Foster City, CA, Parsippany, NJ or Santa Monica, CA.
Kite is transitioning from its current Santa Monica headquarters, with employees expected to relocate to our El Segundo office beginning in January 2027. While this role will be based in Santa Monica through 2026, applicants should take this planned relocation into consideration. Kite supports a flexible working policy, offering a balanced approach with two days of remote working and three days working onsite
Key Accountabilities:
  • Provide scientific and financial leadership for the execution and communication of real-world evidence across the product lifecycle.
  • Lead design and oversight of observational studies (retrospective/prospective cohorts, registries, external control arms).
  • Ensure methodological rigor is incorporated into study conceptualization, protocol and analysis.
  • Application of advanced epidemiologic and statistical methods (e.g., propensity score methods, survival analysis, causal inference).
  • Translate complex analyses into clear, decision-relevant insights for internal and external stakeholders.
  • Partner closely with Clinical Development, Biostatistics, Medical Affairs, HEOR, Regulatory Affairs, Value & Access, and Commercial teams to align evidence generation with business needs.
  • Provide RWE expertise and input for regulatory filings (e.g. MAA, BLA, sBLA) as well as response to questions from regulatory authorities and HTA agencies.
  • Engage with external collaborators, registries, academic partners, and data vendors.
  • Ensure scientific rigor, transparency, and reproducibility consistent with internal RWE standard.
  • Oversee vendors and ensure timely, high-quality study delivery.

Minimum Required Education and Years of Experience
  • Bachelor's Degree and Ten Years' Experience OR
  • Masters' Degree and Eight Years' Experience OR
  • PhD and Two Years' Experience

Preferred Education and Qualifications:
  • Doctoral degree (e.g. PhD, MD, ScD, PharmD) in Epidemiology or related discipline, such as Outcomes Research, Medicine, Biostatistics from an accredited institution, with a minimum of 6+ years of relevant, post-graduation experience with doctoral training OR Master's degree (e.g. MSc) in Epidemiology or related discipline, such as Outcomes Research, Medicine, Biostatistics from an accredited institution with 8+ years of relevant experience with Master's training.
  • Deep understanding of observational study design and causal inference, real-world data sources, bias, confounding, and sensitivity analyses.
  • Understanding of the RWE regulatory landscape preferred.
  • Experience in working with international data sets and/or Common Data Models (e.g., OMOP) preferred.
  • Strong technical reading, writing and communication skills
  • Prior corporate experience in hematology/oncology therapeutic area is highly preferred-Minimum of four (4) years of professional experience in the biopharmaceutical industry

People Leader Accountabilities
Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.
Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.
Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.
The salary range for this position is:
Bay Area: $195,670.00 - $253,220.00.
Other US Locations: $177,905.00 - $230,230.00.
Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
For jobs in the United States:
Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Kite Pharma Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday.

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