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Director Real World Evidence Jobs (NOW HIRING)

Jazz Pharmaceutical

Director, Real World Evidence

$204K - $306K/yr

The Director of Real-World Evidence (RWE) will provide (scientific/strategic/tactical/etc) leadership for RWE studies and analyses using administrative claims data and EMR, reporting to the Head of ...

Precision Medicine Group

Director Real World Evidence

$140K - $180K/yr

Our Real World Evidence team is hiring a Director to lead teams of research professionals conducting client studies in the pharmacy and biotech space; operating as a thought leader, problem solver ...

Precision AQ

Director Real World Evidence

$140K - $180K/yr

Our Real World Evidence team is hiring a Director to lead teams of research professionals conducting client studies in the pharmacy and biotech space; operating as a thought leader, problem solver ...

Precision for Medicine

Director Real World Evidence

$140K - $180K/yr

Our Real World Evidence team is hiring a Director to lead teams of research professionals conducting client studies in the pharmacy and biotech space; operating as a thought leader, problem solver ...

Novo Nordisk

Real World Evidence Director

Plainsboro, NJ · On-site

$225K - $300K/yr

The Position The Director, Real World Evidence (RWE) leads the development and execution of RWE for the assigned therapeutic area or function area through serving as the principal investigator on ...

Natera

OR · On-site

We are seeking a Principal Clinical Scientist / Associate Director of Real-World Evidence & Epidemiology to drive observational evidence strategy for our Early Cancer Detection (ECD) portfolio.

Lancesoft INC

Real-World Evidence

Spring House, PA · On-site

$55 - $58/hr

Senior Manager - Real-World Evidence (RWE), Immunology Location: 1400 Mckean Road, Spring House PA 19477 Duration: 07/13/2026 to 07/12/2027(12 Months) Notes from Manager: - Role can be REMOTE ...

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How much do director real world evidence jobs pay per year?

As of Jun 30, 2026, the average yearly pay for director real world evidence in the United States is $123,955.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $137,000.00 per year, depending on experience, location, and employer.

What is the difference between Director Real World Evidence vs Clinical Data Manager?

AspectDirector Real World EvidenceClinical Data Manager
Required CredentialsAdvanced degree (PhD, MD, or Master’s), experience in RWE, biostatisticsBachelor’s or Master’s in life sciences, clinical research, or related field
Work EnvironmentStrategic, cross-functional teams, focus on observational studiesData collection, database management, clinical trial support
Employer & Industry UsagePharmaceutical, biotech companies, healthcare analyticsClinical research organizations, hospitals, pharma companies
Common Search & Comparison IntentUnderstanding senior roles in RWEOperational data management roles in clinical trials

The main difference is that the Director of Real World Evidence focuses on strategic analysis of observational data to inform healthcare decisions, while a Clinical Data Manager handles the operational aspects of managing clinical trial data. Both roles require strong scientific backgrounds but differ in scope and responsibilities.

What is a Director of Real World Evidence?

A Director of Real World Evidence (RWE) is a senior professional in the healthcare or pharmaceutical industry responsible for overseeing the collection and analysis of real-world data to generate insights about the use, safety, and effectiveness of medical products. They lead teams that design and implement studies using data from sources like electronic health records, insurance claims, and patient registries. Their work helps inform regulatory decisions, support product development, and improve patient outcomes. The role requires expertise in epidemiology, data science, and regulatory requirements, as well as strong leadership and communication skills.

What are the key skills and qualifications needed to thrive as a Director of Real World Evidence, and why are they important?

To thrive as a Director of Real World Evidence, you need advanced expertise in epidemiology, biostatistics, and data analytics, typically supported by a graduate degree in a related field and significant experience in pharmaceutical or healthcare research. Mastery of statistical software (such as SAS, R, or Python), familiarity with real-world data sources (like claims or EMR databases), and knowledge of regulatory guidelines are crucial. Exceptional leadership, communication, and stakeholder management skills distinguish top performers in this role. These competencies ensure robust evidence generation, effective cross-functional collaboration, and impactful decision-making that drives value for healthcare organizations.

How does a Director of Real World Evidence typically collaborate with cross-functional teams to drive evidence generation projects?

A Director of Real World Evidence (RWE) works closely with clinical, regulatory, medical affairs, biostatistics, and data science teams to design and execute studies that generate actionable insights from real-world data. This role often involves leading project teams, aligning stakeholder objectives, and ensuring that RWE strategies support both product development and post-market decision-making. Effective communication and project management skills are essential, as the Director must synthesize input from diverse experts, manage timelines, and ensure that evidence generation aligns with regulatory and business goals.
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Director Real World Evidence jobs near you
Infographic showing various Director Real World Evidence job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 84% Full Time, 13% Part Time, 1% Temporary, and 1% Contract. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $123,955 per year, or $59.6 per hour.

Director, Real World Evidence

Jazz Pharmaceutical

Remote

$204K - $306K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 14 days ago

Job description

If you are a current Jazz employee please apply via the Internal Career site
Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.
Job Description
Brief Description:
The Director of Real-World Evidence (RWE) will provide (scientific/strategic/tactical/etc) leadership for RWE studies and analyses using administrative claims data and EMR, reporting to the Head of RWE. The Director of RWE will function on an analytics team responsible for establishing rigorous assessments of administrative claims data and EMR to evaluate real-world outcomes for all Jazz products. The incumbent will provide exceptional leadership for projects under his/her direct responsibility and oversee the tactical planning and execution of RWE projects conducted by the internal and external RWE analytic team. The candidate will also ensure the timeliness and delivery of scientifically valid research.
Essential Functions/Responsibilities
  • Develop RWE strategies for one or multiple molecules, in collaboration with internal partners, to ensure that the value of Jazz products is fully supported by evidence for global and regional audiences.
  • Drive RWE innovations and effective communication to internal stakeholders, regulatory, health technology assessment bodies and scientific communities; continuously strive to publish results in peer-review journals and conferences.
  • Lead the design and execution of RWE research projects using administrative claims data/ EMR including development of protocols and contribute to statistical analysis plans (SAPs).
  • Responsible for RWE leadership across internal cross-functional teams. Leverage advanced communication and translation skills and strategic planning across health economics and outcomes research, medical affairs and clinical development functions.
  • Support the Head of Head of Medical Affairs Statistics, Epidemiology and RWE in developing and implementing operational processes for internal department as it relates to daily RWE activities.
  • Assess real-world data assets and establish data curation plans, including provisioning data licenses and data platforms, in collaboration with Medical Affairs statistics, epidemiology and RWE leadership team.
  • Stay current with research on RWE methodology and its applications as pertinent to project needs.

Required Knowledge, Skills, and Abilities
  • PhD degree in epidemiology (or related discipline) with research experience
  • Analytic experience of healthcare claims databases and EMR
  • Familiarity with US and global health care delivery system (eg. payers and reimbursement models)
  • Experience in designing, collecting and analyzing RWE using administrative claims datasets, EMRs, and patient charts
  • Strong analytical skills and ability to work with multi-disciplinary teams required to support program, project and contract management and financial reporting
  • Experience with big data analytical platforms
  • A track record of peer-reviewed scientific publications demonstrating expertise in RWE
  • Demonstrated strategic and conceptual skills to develop innovative approaches for developing product differentiation

Required/Preferred Education and Licenses
  • PhD in epidemiology or related discipline

#LI-SM1
#LI-remote
Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.
FOR US BASED CANDIDATES ONLY
Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is:
$204,000.00 - $306,000.00
Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.
At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.
The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html

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