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Protein Purification Process Development Jobs (NOW HIRING)

Lonza

Scientist II, Downstream

Houston, TX · On-site

Experience with development and optimization of viral or protein purification process including chromatography, filtration and formulation unit operations. * Experience with the technology ...

Lonza

Scientist II, Downstream

Houston, TX

Experience with development and optimization of viral or protein purification process including chromatography, filtration and formulation unit operations. * Experience with the technology ...

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Protein Purification Process Development information

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How much do protein purification process development jobs pay per hour?

As of Jun 27, 2026, the average hourly pay for protein purification process development in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.

What is the difference between Protein Purification Process Development vs Protein Purification Technician?

AspectProtein Purification Process DevelopmentProtein Purification Technician
CredentialsBachelor's or higher in Biochemistry, Molecular Biology, or related fieldsAssociate's or Bachelor's in Life Sciences or related areas
Work EnvironmentResearch labs, development facilities, collaborative teamsManufacturing or production labs, hands-on processing
ResponsibilitiesDesigning protocols, optimizing purification methods, process scale-upExecuting purification procedures, operating equipment, maintaining documentation

Protein Purification Process Development professionals focus on designing and optimizing purification methods, often working in research and development settings. In contrast, Protein Purification Technicians perform routine purification tasks, operating equipment in manufacturing environments. Both roles require knowledge of protein chemistry but differ in scope, responsibilities, and work environment.

What is protein purification process development?

Protein purification process development is the design, optimization, and scaling up of methods to isolate and purify proteins from complex biological mixtures. This field involves selecting appropriate techniques like chromatography, filtration, and centrifugation to obtain a protein of interest with high purity and yield. Professionals in this area work on developing efficient, reproducible, and cost-effective processes that can be transferred from laboratory scale to industrial manufacturing. They also ensure the process meets regulatory standards for use in pharmaceuticals, research, or industrial applications.

What are the key skills and qualifications needed to thrive in Protein Purification Process Development, and why are they important?

To excel in Protein Purification Process Development, a strong background in biochemistry, molecular biology, or chemical engineering—often with a relevant degree or advanced degree—is essential. Familiarity with chromatographic techniques (such as HPLC, FPLC), analytical instruments, and regulatory documentation systems like GMP are typically required. Strong problem-solving, attention to detail, and effective collaboration skills help professionals optimize processes and troubleshoot issues. Mastery of these skills ensures the efficient development of scalable purification methods, high product yield, and compliance with quality standards.

What are some common challenges faced during protein purification process development, and how are they typically addressed?

Protein purification process development often involves overcoming challenges such as low protein yield, maintaining protein stability, and removing impurities efficiently. To address these, scientists frequently optimize buffer conditions, select appropriate chromatography methods, and test various purification strategies in small-scale experiments before scaling up. Cross-functional collaboration with analytical and downstream processing teams is essential to troubleshoot issues and ensure process robustness. Continuous learning and adaptability are key, as each protein can present unique purification challenges.
More about Protein Purification Process Development jobs
What states have the most Protein Purification Process Development jobs? States with the most job openings for Protein Purification Process Development jobs include:
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Protein Purification Process Development jobs near you
Infographic showing various Protein Purification Process Development job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 92% Physical, and 8% Remote job distribution, with an average salary of $70,060 per year, or $33.7 per hour.

Associate - Protein Chemistry - Purification

Amgen

Thousand Oaks, CA

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 8 days ago

Job description

Career CategoryScientificJob Description
Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Associate - Protein Chemistry-Purification

What you will do

Let's do this. Let's change the world. Amgenisseekingahighly motivated Associateto join the Protein Therapeutics(PT)-Protein Chemistry team.PT is a multidisciplinary team with broad capabilities in protein engineering, expression, purification, and characterization.Weareresponsible forthe engineering, production, assessment, and finalselectionof large molecule drug candidates that advance to Process Development.

In this role, you will supportthepurificationoflargemolecule, therapeutic drug candidates, many of which are complex biologics.

Responsibilities:

  • Purifying novel and complex molecules that will be the next generation of large molecule therapeutics.

  • Contributing to theexecutionof ourprotein purification and analyticscapabilities.

  • Organizing, analyzing, and reportingfindingsto support lead candidateselection.

  • Partnering with Project, Analytics and Automation teams to advance our pipeline.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional weseekis a highly collaborative, motivated scientist with these qualifications.

Basic Qualifications:

Bachelor's degree inlife sciences.

OR

Associate'sdegree and4years of relevant scientific experience

OR

High school diploma / GED and 6 years of protein purification, and/or protein analytics experience.

Preferred Qualifications:

  • Demonstratedstrong communicationskills,ability to multi-task and work collaboratively in a cross-functional team environment.

  • Demonstratedtrack recordof independent critical thinking and creative problem-solving.

  • Experiencewithprotein purification, chromatography resins,instrumentation,andsoftware.

  • Familiarity with protein analytics fundamentals and techniques.

  • Familiarity with handlingand analyzinglarge datasets.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans

  • Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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Salary Range

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