ZipRecruiter

Log In

1

Protein Purification Process Development Jobs in California

3 Key Consulting

$36 - $41/hr

Engineer - Biologics Purification Process Development & Purification (JP14792) Location: Thousand Oaks, CA. 91320 Hybrid Employment Type: Contract Business Unit: Drug Substance Technology Engineering ...

Gilead

Scientist, Process Development

Foster City, CA

$146K - $189K/yr

Scientist, Purification Process Development - Pre-Pivotal Biologics - Foster City, CA The Scientist, Purification Process Development (Pre-Pivotal) will lead and execute purification process ...

next page

Showing results 1-20

All JobsProtein Purification Process Development JobsProtein Purification Process Development Jobs in California

Protein Purification Process Development information

See California salary details

$18

$33

$48

How much do protein purification process development jobs pay per hour?

As of Jun 14, 2026, the average hourly pay for protein purification process development in California is $33.24, according to ZipRecruiter salary data. Most workers in this role earn between $27.26 and $40.82 per hour, depending on experience, location, and employer.

What is the difference between Protein Purification Process Development vs Protein Purification Technician?

AspectProtein Purification Process DevelopmentProtein Purification Technician
CredentialsBachelor's or higher in Biochemistry, Molecular Biology, or related fieldsAssociate's or Bachelor's in Life Sciences or related areas
Work EnvironmentResearch labs, development facilities, collaborative teamsManufacturing or production labs, hands-on processing
ResponsibilitiesDesigning protocols, optimizing purification methods, process scale-upExecuting purification procedures, operating equipment, maintaining documentation

Protein Purification Process Development professionals focus on designing and optimizing purification methods, often working in research and development settings. In contrast, Protein Purification Technicians perform routine purification tasks, operating equipment in manufacturing environments. Both roles require knowledge of protein chemistry but differ in scope, responsibilities, and work environment.

What is protein purification process development?

Protein purification process development is the design, optimization, and scaling up of methods to isolate and purify proteins from complex biological mixtures. This field involves selecting appropriate techniques like chromatography, filtration, and centrifugation to obtain a protein of interest with high purity and yield. Professionals in this area work on developing efficient, reproducible, and cost-effective processes that can be transferred from laboratory scale to industrial manufacturing. They also ensure the process meets regulatory standards for use in pharmaceuticals, research, or industrial applications.

What are the key skills and qualifications needed to thrive in Protein Purification Process Development, and why are they important?

To excel in Protein Purification Process Development, a strong background in biochemistry, molecular biology, or chemical engineering—often with a relevant degree or advanced degree—is essential. Familiarity with chromatographic techniques (such as HPLC, FPLC), analytical instruments, and regulatory documentation systems like GMP are typically required. Strong problem-solving, attention to detail, and effective collaboration skills help professionals optimize processes and troubleshoot issues. Mastery of these skills ensures the efficient development of scalable purification methods, high product yield, and compliance with quality standards.

What are some common challenges faced during protein purification process development, and how are they typically addressed?

Protein purification process development often involves overcoming challenges such as low protein yield, maintaining protein stability, and removing impurities efficiently. To address these, scientists frequently optimize buffer conditions, select appropriate chromatography methods, and test various purification strategies in small-scale experiments before scaling up. Cross-functional collaboration with analytical and downstream processing teams is essential to troubleshoot issues and ensure process robustness. Continuous learning and adaptability are key, as each protein can present unique purification challenges.
What are popular job titles related to Protein Purification Process Development jobs in California? For Protein Purification Process Development jobs in California, the most frequently searched job titles are:
What job categories do people searching Protein Purification Process Development jobs in California look for? The top searched job categories for Protein Purification Process Development jobs in California are:
Protein Purification Process Development jobs near you
Infographic showing various Protein Purification Process Development job openings in California as of June 2026, with employment types broken down into 1% As Needed, 80% Full Time, 16% Part Time, and 3% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $69,143 per year, or $33.2 per hour.
Purification Process Expert-Scientist

Purification Process Expert-Scientist

Artech Information System LLC

Emeryville, CA • On-site

Contractor

Posted 17 days ago

Job description

Company Description

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.

Job Description

As a Subject Matter Expert/tech lead in recombinant protein Purification processes.

Identify process or method improvements for microbially produced immune Diagnostics antigen products, support commercial manufacturing & lead technology transfers into Manufacturing.

Subject Matter Expert in protein Purification process design and improvement & technical transfer to manufacturing.

Liaise w/Laboratory Managers & negotiate appropriate resource needs & timelines for studies

Provide supervision & mentoring to Laboratory Associates during performance of studies

Be a resource to other departments as Subject Matter Expert for product & process knowledge.

Design & develop downstream process, scale-up, & DOE studies.

Support technology transfer of scaled up processes into commercial Manufacturing.

Ensure process characterization studies / technical batches generate sufficient process knowledge by thoroughly testing critical variables.

Implement new process or analytical technologies into manufacturing.

Assist in statistical analysis of data & identify studies to improve process capability (CpK) and/or yield & reduce cost of goods

Author scientific study protocols & reports for identified studies in their area of expertise

Lead studies to characterize Purification process parameters in the risk assessments to define their criticality & to define Proven Acceptable Ranges (PAR) for Critical Process Parameters (CPPs)

Identify process improvements opportunities for commercial Manufacturing, studies includes but not limited to purification process parameters improvement, resin/membrane screening & scale down/up.

Provide technical guidance for Change Controls for the implementation of downstream Purification process changes

Perform evaluations of downstream process change requests as needed.

Lead or assist in investigations relating to Manufacturing or QC deviations & Out of Specifications (OOSs) & develop studies to determine their root causes

Design studies & experiments to support process/method improvement or changes & to support closure of discrepancy events or deviations

Use scientific & statistical knowledge to analyze data to provide process understanding, & to identify root causes of product & process failures.

Provide front line support to manufacturing, working with the shift teams focusing on manufacturing each batch safely, on time, in compliance with the batch instructions & quality requirements

Validation support to develop & drive stage 1 requirements to support product life cycle management.

Working with manufacturing support group, execution & review of protocol/report, assure consistency of master batch records, support in Deviation, Out Of Expectation, Out Of Specification, CAPAs, complaint handling.


Skills:  

Strong knowledge of protein purification & protein chemistry techniques including: column chromatography (IEX, HIC, IMAC, SEC, RP, mix mode, affinity) & membrane chromatography, depth filtration, centrifugation, UF/DF

Analytical skills (SDS-PAGE, western blots, IEF, UV/Vis spectrophotometry, HPLC, ELISA, etc.

Extensive working knowledge of Purification process development for recombinant protein expression & purification including operational proficiency with AKTA Explorer / AKTA Pilot / AKTA Crossflow, Sci-Log TFF, large scale column packing, testing are required.

Prior Project Leadership of at least 1 project of moderate scope implementing a change into Manufacturing or QC

Experience in technology transfer of processes or methods from non-GMP to GMP environments

Knowledgeable in cGMP environments & in particular of process validation strategies & requirements

Thorough knowledge of the use of statistics & design of experiments to test hypotheses

Excellent written, verbal & presentation communication skills

Local language: English

Capable of effective use of Microsoft Word, Excel & PowerPoint

Strong working knowledge of DOE approaches & programs such as JMP or Minitab for experimental design

Good knowledge of Project Management tools including prior leadership of at least 1 project with a moderately complex scope

Knowledge of business principles including the interactions needed between departments to successfully complete projects


Qualifications

B.Sc./M.Sc./Ph.D. in Chemical Engineering/ Biochemical Engineering or Life Sciences, Chemistry/Biochemistry or related discipline

2 years experiences with a Ph.D. or 5 years experiences with a B.Sc./M.Sc. in a Purification Process Development in the biotechnology or diagnostics industry.


Additional Information

For more information, Please contact

Akriti Gupta

(973) 967-3409

Morristown, NJ 07960 


Artech logo

About Artech

Sourced by ZipRecruiter

Artech is a leading IT staffing and consulting company based in Morristown, NJ, US. Since its foundation in 1992, Artech has mastered in complementing human expertise with technology and business acumen to produce world-class staffing solutions. The company caters to diverse industry sectors, including financial services, healthcare, telecommunication, energy and utilities, supply chain, and retail. It provides IT consulting, project management, professional and staff augmentation, and managed staffing services. Artech's mission is to provide exceptional IT staffing services to its clients by comprehending their business needs and then crafting a customized staffing strategy. Its notable achievement includes being recognized as one of the largest IT staffing companies in the U.S, according to Staffing Industry Analysts (SIA).

Industry

Recruiting and staffing services

Company size

10,000+ Employees

Headquarters location

Morristown, NJ, US

Year founded

1992

View All Artech Jobs

Apply