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Protein Purification Process Development Jobs (NOW HIRING)

LabPersonnel

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Protein Production Scientist

Lemont, IL · On-site

$27/hr

Work site location = Lemont, IL Major Responsibilities: 1. Protein Purification and Processing · Identify optimal elastic protein expression clones through high-throughput screening in E. coli ...

Adecco

Scientist III

Swiftwater, PA

$80/hr

This position is ideal for scientists with strong protein purification expertise and hands-on experience with chromatography, filtration, scale-up activities, and process development in regulated ...

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Protein Purification Process Development information

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$18

$33

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How much do protein purification process development jobs pay per hour?

As of Jun 27, 2026, the average hourly pay for protein purification process development in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.

What is the difference between Protein Purification Process Development vs Protein Purification Technician?

AspectProtein Purification Process DevelopmentProtein Purification Technician
CredentialsBachelor's or higher in Biochemistry, Molecular Biology, or related fieldsAssociate's or Bachelor's in Life Sciences or related areas
Work EnvironmentResearch labs, development facilities, collaborative teamsManufacturing or production labs, hands-on processing
ResponsibilitiesDesigning protocols, optimizing purification methods, process scale-upExecuting purification procedures, operating equipment, maintaining documentation

Protein Purification Process Development professionals focus on designing and optimizing purification methods, often working in research and development settings. In contrast, Protein Purification Technicians perform routine purification tasks, operating equipment in manufacturing environments. Both roles require knowledge of protein chemistry but differ in scope, responsibilities, and work environment.

What is protein purification process development?

Protein purification process development is the design, optimization, and scaling up of methods to isolate and purify proteins from complex biological mixtures. This field involves selecting appropriate techniques like chromatography, filtration, and centrifugation to obtain a protein of interest with high purity and yield. Professionals in this area work on developing efficient, reproducible, and cost-effective processes that can be transferred from laboratory scale to industrial manufacturing. They also ensure the process meets regulatory standards for use in pharmaceuticals, research, or industrial applications.

What are the key skills and qualifications needed to thrive in Protein Purification Process Development, and why are they important?

To excel in Protein Purification Process Development, a strong background in biochemistry, molecular biology, or chemical engineering—often with a relevant degree or advanced degree—is essential. Familiarity with chromatographic techniques (such as HPLC, FPLC), analytical instruments, and regulatory documentation systems like GMP are typically required. Strong problem-solving, attention to detail, and effective collaboration skills help professionals optimize processes and troubleshoot issues. Mastery of these skills ensures the efficient development of scalable purification methods, high product yield, and compliance with quality standards.

What are some common challenges faced during protein purification process development, and how are they typically addressed?

Protein purification process development often involves overcoming challenges such as low protein yield, maintaining protein stability, and removing impurities efficiently. To address these, scientists frequently optimize buffer conditions, select appropriate chromatography methods, and test various purification strategies in small-scale experiments before scaling up. Cross-functional collaboration with analytical and downstream processing teams is essential to troubleshoot issues and ensure process robustness. Continuous learning and adaptability are key, as each protein can present unique purification challenges.
More about Protein Purification Process Development jobs
What states have the most Protein Purification Process Development jobs? States with the most job openings for Protein Purification Process Development jobs include:
What job categories do people searching Protein Purification Process Development jobs look for? The top searched job categories for Protein Purification Process Development jobs are:
Protein Purification Process Development jobs near you
Infographic showing various Protein Purification Process Development job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 92% Physical, and 8% Remote job distribution, with an average salary of $70,060 per year, or $33.7 per hour.
Protein Production Scientist

Protein Production Scientist

LabPersonnel

Lemont, IL • On-site

$27/hr

Full-time

Medical, PTO

Posted 15 days ago

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Job description

Research Assistant – Protein Production Scientist at Argonne National Laboratory, Lemont, IL


Our client, Argonne National Laboratory is hosting a new early-stage biotech startup developing recombinant elastic and thermoresponsive protein materials to enable fully bio-based, high-performance stretch in textiles. Our work integrated protein engineering, bioprocessing, and materials characterization to support circular and scalable textile innovation.

The team is searching for a contract scientist to support recombinant protein purification, sample

preparation, and materials characterization in collaboration with internal teams, contract research

partners, and national lab user facilities.

Project Length = 3 Months.

Work site location = Lemont, IL

Major Responsibilities:

1. Protein Purification and Processing

·        Identify optimal elastic protein expression clones through high-throughput screening in E. coli systems.

2. Collaborator & Contract Research Support

·        Prepare, document, and ship protein and material samples to external collaborators

·        Receive cell pellets from partners for downstream processing

3. Materials Characterization Support

·        Support characterization of structural, mechanical, and chemical properties of materials across form factors (protein, fiber, non-woven, woven)

·        Assist with sample preparation and data collection for techniques such as SEM, spectroscopy, and related analyses.

4. Project & Lab Support

·        Maintain protocols and documentation

·        Communicate results with internal teams and external partners

·        Support iterative optimization based on characterization feedback

Required Skills:

·        BS or MS in Biochemical Engineering, Molecular Biology, Biochemistry.

·        Minimum of 1 year of proficiency in relevant instrumentation or experience in areas of specialized expertise as identified by the program requirements.

·        Hands-on expertise in recombinant protein purification and analytical characterization

                            (e.g., SDS-PAGE)

·        Familiarity with biomaterials processing and/or textile-relevant material formats preferred

·        Experience supporting collaborative or multi-institution research projects strongly preferred

·        Strong organization, documentation, and communication skills.

If you would like to be considered for this role, you need to submit your resume before 6/14/26.

If you or anyone you know is interested, qualified and immediately available please send an updated resume to us for immediate review and consideration.

Company Description

LabPersonnel is not a general staffing firm, we specialize on recruitment in the Engineering, Pharma, Food, Energy, Power, Oil & Gas, Chemical, Paints and Petroleum.
As market specialists in these areas we understand your market and product solutions in considerable depth. This knowledge plays a key role in the process that enables us to source the best candidates using the most time efficient methods.