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Protein Purification Process Development Jobs (NOW HIRING)

Biochemist

Tarrytown, NY · On-site

$40 - $55/hr

Familiarity with protein development and purification processing of therapeutic reagents. * Demonstrated ability to think proactively about future solutions while addressing current technical ...

Biochemist

Tarrytown, NY · On-site

$40 - $55/hr

Familiarity with protein development and purification processing of therapeutic reagents. * Demonstrated ability to think proactively about future solutions while addressing current technical ...

Biochemist

Tarrytown, NY · On-site

$40 - $55/hr

Familiarity with protein development and purification processing of therapeutic reagents. * Demonstrated ability to think proactively about future solutions while addressing current technical ...

Scientist - Purification Process Development Location: Waltham, MA Schedule: Full-Time | Onsite Pay ... Protein purification chromatography * AKTA chromatography systems * Depth filtration * Tangential ...

This position is ideal for scientists with strong protein purification expertise and hands-on experience with chromatography, filtration, scale-up activities, and process development in regulated ...

Scientist, Purification Process Development - Pre-Pivotal Biologics - Foster City, CA The Scientist, Purification Process Development (Pre-Pivotal) will lead and execute purification process ...

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Protein Purification Process Development information

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$49

How much do protein purification process development jobs pay per hour?

As of Jun 5, 2026, the average hourly pay for protein purification process development in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in Protein Purification Process Development, and why are they important?

To excel in Protein Purification Process Development, a strong background in biochemistry, molecular biology, or chemical engineering—often with a relevant degree or advanced degree—is essential. Familiarity with chromatographic techniques (such as HPLC, FPLC), analytical instruments, and regulatory documentation systems like GMP are typically required. Strong problem-solving, attention to detail, and effective collaboration skills help professionals optimize processes and troubleshoot issues. Mastery of these skills ensures the efficient development of scalable purification methods, high product yield, and compliance with quality standards.

What are some common challenges faced during protein purification process development, and how are they typically addressed?

Protein purification process development often involves overcoming challenges such as low protein yield, maintaining protein stability, and removing impurities efficiently. To address these, scientists frequently optimize buffer conditions, select appropriate chromatography methods, and test various purification strategies in small-scale experiments before scaling up. Cross-functional collaboration with analytical and downstream processing teams is essential to troubleshoot issues and ensure process robustness. Continuous learning and adaptability are key, as each protein can present unique purification challenges.

What is protein purification process development?

Protein purification process development is the design, optimization, and scaling up of methods to isolate and purify proteins from complex biological mixtures. This field involves selecting appropriate techniques like chromatography, filtration, and centrifugation to obtain a protein of interest with high purity and yield. Professionals in this area work on developing efficient, reproducible, and cost-effective processes that can be transferred from laboratory scale to industrial manufacturing. They also ensure the process meets regulatory standards for use in pharmaceuticals, research, or industrial applications.

What is the difference between Protein Purification Process Development vs Protein Purification Technician?

AspectProtein Purification Process DevelopmentProtein Purification Technician
CredentialsBachelor's or higher in Biochemistry, Molecular Biology, or related fieldsAssociate's or Bachelor's in Life Sciences or related areas
Work EnvironmentResearch labs, development facilities, collaborative teamsManufacturing or production labs, hands-on processing
ResponsibilitiesDesigning protocols, optimizing purification methods, process scale-upExecuting purification procedures, operating equipment, maintaining documentation

Protein Purification Process Development professionals focus on designing and optimizing purification methods, often working in research and development settings. In contrast, Protein Purification Technicians perform routine purification tasks, operating equipment in manufacturing environments. Both roles require knowledge of protein chemistry but differ in scope, responsibilities, and work environment.

More about Protein Purification Process Development jobs
What states have the most Protein Purification Process Development jobs? States with the most job openings for Protein Purification Process Development jobs include:
What job categories do people searching Protein Purification Process Development jobs look for? The top searched job categories for Protein Purification Process Development jobs are:
Biochemist

Biochemist

Actalent

Tarrytown, NY • On-site

$40 - $55/hr

Contractor

Medical, Dental, Vision, Life, Retirement, PTO

This job post has expired 1 day ago. Applications are no longer accepted.


Job description

Job Description

This role focuses on the purification and characterization of therapeutic protein reagents and antibodies to support ongoing therapeutic programs. The biochemist operates standard and automated purification systems, performs detailed analytical characterization, and documents and communicates findings clearly to project teams in a fast-paced, collaborative laboratory environment.

Responsibilities

  • Purify therapeutic reagents and antibodies using standard protein purification systems and automated equipment.
  • Perform protein purification and characterization by liquid chromatography techniques, including affinity chromatography, ion exchange (IEX), hydrophobic interaction chromatography (HIC), and size exclusion chromatography (SEC).
  • Conduct protein characterization using Western blotting, SDS-PAGE electrophoresis, capillary electrophoresis SDS (CE-SDS), SEC chromatography, and spectrophotometry.
  • Enter, analyze, and document data for purified and characterized reagents in Benchling and other data management tools.
  • Prepare clear and concise presentations to summarize experimental results and conclusions.
  • Communicate results, issues, and progress effectively to peers and leadership.
  • Work productively in a fast-paced, collaborative team environment within a Protein Development group.
  • Apply strong attention to detail and maintain high quality standards in experimental design, execution, and documentation.
  • Manage multiple tasks and experiments simultaneously while maintaining strong organizational practices.
  • Contribute to solving current technical challenges while proactively thinking about future improvements and solutions in purification and characterization workflows.

Essential Skills

  • Bachelor’s or Master’s degree in Biochemistry, Chemistry, Chemical Engineering, or a related field.
  • At least 2 years of industry or research laboratory experience.
  • Hands-on experience with protein purification using standard and automated systems.
  • Proficiency in protein characterization techniques, including SDS-PAGE, Western blotting, SEC, and related analytical methods.
  • Experience with liquid chromatography methods such as affinity, IEX, HIC, and SEC.
  • Ability to accurately enter, analyze, and document experimental data in electronic systems such as Benchling.
  • Strong organizational skills and the ability to manage multiple experiments and priorities.
  • Excellent verbal and written communication skills for clear reporting and presentation of results.
  • Proven ability to work productively in a fast-paced, collaborative team environment.
  • High attention to detail and a strong commitment to data quality and reproducibility.

Additional Skills & Qualifications

  • Experience using CE-SDS and spectrophotometry for protein analysis.
  • Familiarity with protein development and purification processing of therapeutic reagents.
  • Demonstrated ability to think proactively about future solutions while addressing current technical challenges.
  • Comfort working with automated laboratory equipment and modern data management tools.
  • Interest in contributing to the development of innovative therapeutic proteins within a growing organization.

Work Environment

This is a full-time, Monday–Friday onsite position in a laboratory setting within a Protein Development group. The role involves working with standard and automated protein purification systems and a range of analytical instruments such as liquid chromatography systems, electrophoresis equipment, and spectrophotometers. The environment is fast-paced and highly collaborative, with a strong focus on scientific excellence and innovation. The broader organization offers a well-regarded company culture, a track record of multiple FDA-approved medicines, and significant internal research and development capabilities.

Job Type & Location

This is a Contract position based out of Tarrytown, NY.

Pay and Benefits

The pay range for this position is $40.00 - $55.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:
• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Tarrytown,NY.

Application Deadline

This position is anticipated to close on Jun 15, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.


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About Actalent

Sourced by ZipRecruiter

Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We're supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions.

Company size

5,001 - 10,000 Employees

Headquarters location

Hanover, MD, US

Year founded

1983

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