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Process Optimization Manager Jobs in Pennsylvania

Senior Cement Plant Manager

Indiana, PA · On-site

$193.71 - $258.27/hr

... process optimization, and asset reliability enhancements.**What Are We Looking For*** Extensive ... Strong business acumen, including budgeting, capital project management, and operational decision ...

Senior Cement Plant Manager

Indiana, PA · On-site

$193.71 - $258.27/hr

... process optimization, and asset reliability enhancements. What Are We Looking For Extensive ... Strong business acumen, including budgeting, capital project management, and operational decision ...

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Showing results 41-60

Process Optimization Manager information

See Pennsylvania salary details

$34.1K

$102K

$166.9K

How much do process optimization manager jobs pay per year?

As of Aug 12, 2026, the average yearly pay for process optimization manager in Pennsylvania is $101,977.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,700.00 and $129,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a process optimization manager?

To thrive as a Process Optimization Manager, you need expertise in process improvement methodologies (such as Lean or Six Sigma), analytical problem-solving skills, and a relevant degree in engineering, business, or operations management. Familiarity with data analysis tools (like Excel, Minitab, or Tableau) and relevant certifications (such as Six Sigma Green or Black Belt) are typically expected. Strong communication, leadership, and change management abilities help drive cross-functional collaboration and gain buy-in for process changes. These skills and qualities are crucial for identifying inefficiencies, implementing sustainable improvements, and achieving organizational goals.

What does a process optimization manager do?

A process optimization manager analyzes and improves business processes to increase efficiency, reduce costs, and enhance quality. They use tools like data analysis, workflow mapping, and lean or Six Sigma methodologies to identify areas for improvement and implement solutions, often collaborating with cross-functional teams. Strong analytical skills and knowledge of process improvement techniques are essential for this role.

What is a process optimization manager?

Process Optimization Managers are professionals who analyze, improve, and streamline business processes to increase efficiency, reduce costs, and enhance overall organizational performance. They use data-driven approaches to identify bottlenecks and implement best practices or new technologies. Their role often involves collaborating with various departments, managing change initiatives, and ensuring continuous improvement across operations. Strong analytical, project management, and communication skills are essential for success in this position.

What are some common challenges process optimization managers face when implementing new process improvements?

Process Optimization Managers often encounter resistance to change from team members who are accustomed to established workflows. Balancing stakeholder expectations while ensuring that improvements align with organizational goals can be challenging. Additionally, gathering and analyzing accurate data to identify bottlenecks requires strong collaboration with cross-functional teams. Successfully navigating these challenges involves clear communication, fostering a culture of continuous improvement, and providing adequate training and support during transitions.
What are the most commonly searched types of Process Optimization jobs in Pennsylvania? The most popular types of Process Optimization jobs in Pennsylvania are:
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What job categories do people searching Process Optimization Manager jobs in Pennsylvania look for? The top searched job categories for Process Optimization Manager jobs in Pennsylvania are:
What cities in Pennsylvania are hiring for Process Optimization Manager jobs? Cities in Pennsylvania with the most Process Optimization Manager job openings:
Infographic showing various Process Optimization Manager job openings in Pennsylvania as of August 2026, with employment types broken down into 1% As Needed, 74% Full Time, 20% Part Time, 3% Contract, and 2% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $101,977 per year, or $49 per hour.

Process Development CMC Leader - Bioconjugation

Abzena Inc.

Bristol, PA • On-site

Full-time

Re-posted 3 days ago


Job description

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.
Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.
We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.
We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.
The Process Development CMC Leader leads, manages and develops a cross-functional team of scientists, engineers and research associates focused on the development of chromatography and purification processes for complex bioconjugates. The CMC leader drives all aspects of process development establishing scalable, robust processes which meet facility fit and product quality requirements for early and late phase client programs. Demonstrates ingenuity, creativity and resourcefulness managing a team of associates in all experimentation. Ensures responsiveness to clients and overall client satisfaction. Proposes, plans and implements long range technology programs that drive business value. Functions as an advisor to management in long range company planning.
Responsibilities
  • Lead and mentor a team of scientists and engineers in the design, development and transfer of chromatography and purification processes for complex bioconjugates. Lead optimization of processes to improve efficiency, facility fit, yield and product quality to meet client requirements.
  • Drive the planning, execution and completion of the development activities ensuring adherence to the technical and timeline requirements. Monitor project progress and identify, evaluate and mitigate risks as necessary to meet program objectives.
  • Manage the work activities of the group, resource planning and allocation, client communication, technical document generation and review, mentoring technical staff and troubleshooting process and product-related issues.
  • Provide expert technical guidance, mentorship and training to team members fostering a collaborative and innovative work environment. Accountable for knowledge of the team and application of good practices.
  • Lead process characterization which includes generation of risk assessments, establishment of scale down models, evaluation and classification of process parameters and development of control strategies for commercialization.
  • Review and approve documents including experimental plans, development reports, toxicology production reports, process optimization reports, scale down model protocols and reports, and process characterization protocols and reports.
  • Drive improved collaboration throughout the organization including with cell line development, cell culture development, process chemistry development, analytical method development, manufacturing sciences and technology and manufacturing for achievement of program objectives.
  • Propose and champion innovative solutions that directly contribute to accelerating client programs or increasing business value.
  • Advanced communicator of ideas, project goals and results across functions within the organization and to clients.
  • Participate in and offer significant contributions to organizational strategic planning initiatives.
  • Assist management in their responsibilities.
  • Operate to the highest ethical and moral standards.
  • Comply with Abzena's policies and procedures.
  • Communicate effectively with clients, supervisors, colleagues and staff.
  • Participate effectively as a team player in all aspects of Abzena's business.
  • Adhere to quality standards set by regulations and Abzena policies, procedures, and mission.
  • Perform other duties as assigned.

Qualifications
  • MS degree in applicable scientific field, PhD degree preferred.
  • Minimum either (8) years of directly related experience with a MS degree; with a PhD degree, minimum (5) years industrial experience in process development and cGMP manufacturing including a minimum of (2) years in a leadership role.
  • Ability to work with a high level of scientific independence and direct others.
  • Proven track record and extensive experience in developing and optimizing chromatography and/or purification processes for production of bioconjugates.
  • Demonstrated ability to be solutions driven.
  • Demonstrated experience in managing multiple projects simultaneously.
  • Ability to cultivate a collaborative work environment with a multidisciplinary team.
  • Project and time management skills.
  • Excellent written and verbal communication skills with the ability to present complex data to diverse audiences.
  • Ability to perform successfully under pressure while prioritizing and managing multiple projects or activities.
  • Ability to offer relevant and realistic strategic plans and recommendations.
  • Ability to thrive in a fast-paced, innovative environment while remaining flexible proactive and resourceful.

FLSA: Exempt
Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.