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Principal Toxicologist Jobs (NOW HIRING)

Scorpion Therapeutics

Principal Toxicologist

Raritan, NJ · On-site

$200 - $250/hr

Principal Toxicologist, Toxicology & Biocompatibility, R&D - MedTech (Flex/Hybrid; 3 days/week on-site; no remote). Based within commutable distance of Raritan, NJ (strongly desired) or Cincinnati ...

Exponent Inc.

Principal Toxicologist (Ph.D.)

Oakland, CA · On-site

$200K - $300K/yr

As a Principal Toxicologist, you will lead projects, identify new clients, expand relationships with existing clients, develop technical staff, and develop new business in related Health Sciences ...

Exponent Inc.

Principal Toxicologist (Ph.D.)

Oakland, CA · On-site

$250/hr

As a Principal Toxicologist, you will lead projects, identify new clients, expand relationships with existing clients, develop technical staff, and develop new business in related Health Sciences ...

Integral Consulting Inc

Principal Level Toxicologist

$140K - $210K/yr

Regulatory toxicology and compliance * Human health risk assessment * Consumer product safety and ... Principals are recognized within and beyond the firm as technical and strategic subject matter ...

Abt Associates Inc.

$125 - $150/hr

Working closely with the Principal Investigator and multidisciplinary scientific teams, you will ... Serve as a senior toxicology subject matter expert supporting systematic reviews, evidence ...

Sotera Health

The Principal Consultant - Toxicology is a senior team member within the Technical Consulting Team. The Principal Consultant is responsible for the scientific direction of the program on the Team for ...

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How much do principal toxicologist jobs pay per year?

As of Sep 8, 2026, the average yearly pay for principal toxicologist in the United States is $109,393.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $125,000.00 per year, depending on experience, location, and employer.

What is a principal toxicologist?

A Principal Toxicologist is a senior-level expert who evaluates the safety and potential risks of chemicals, pharmaceuticals, or consumer products on human health and the environment. They design and oversee toxicological studies, interpret data, and ensure regulatory compliance with agencies like the FDA, EPA, or OSHA. Their role often includes guiding risk assessments, advising on product development, and mentoring junior toxicologists.

What are the typical responsibilities of a principal toxicologist?

As a Principal Toxicologist, your day-to-day responsibilities often include designing and overseeing toxicological studies, interpreting complex data, and preparing reports for regulatory submissions. You will frequently interact with multidisciplinary teams such as regulatory affairs, product development, and quality assurance to provide expert guidance on safety and compliance. In many organizations, you may also mentor junior scientists, review study protocols, and stay updated on evolving guidelines and scientific literature. This multi-faceted role offers a balance of hands-on scientific work, leadership, and cross-departmental collaboration.

What are the key skills and qualifications needed to thrive as a principal toxicologist?

A Principal Toxicologist requires advanced expertise in toxicology, pharmacology, and risk assessment, usually supported by a Ph.D. or equivalent experience in a relevant scientific field. Familiarity with regulatory guidelines (such as EPA, FDA, or REACH), laboratory information management systems (LIMS), and data analysis software is essential, as is certification through organizations like DABT when applicable. Strong leadership, strategic thinking, and effective communication skills help drive project teams and provide clear guidance to cross-functional stakeholders. These competencies ensure the Principal Toxicologist can lead complex studies, maintain regulatory compliance, and inform critical decision-making processes.

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Principal Toxicologist jobs near you
Infographic showing various Principal Toxicologist job openings in the United States as of September 2026, with employment types broken down into 90% Full Time, 8% Part Time, 1% Temporary, and 1% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $109,393 per year, or $52.6 per hour.

Principal Toxicologist

Scorpion Therapeutics

Raritan, NJ • On-site

$200 - $250/hr

Other

PTO

Posted 9 days ago

Job description

Principal Toxicologist, Toxicology & Biocompatibility, R&D – MedTech (Flex/Hybrid; 3 days/week on-site; no remote). Based within commutable distance of Raritan, NJ (strongly desired) or Cincinnati, OH.

You Will Be Responsible For:
  • Evaluate medical device products/materials for biological safety per global regulations/standards, GLP (US FDA), and internal procedures.
  • Design/initiate/coordinate/interpret biocompatibility and toxicology laboratory investigations.
  • Apply technical expertise to resolve ISO 10993 biocompatibility issues and regulatory requirements.
  • Coordinate biocompatibility test strategies, review documentation, and ensure deliverables completion.
  • Review/interpret/summarize testing data; support risk assessment documentation.
  • Provide technical guidance to internal/external partners across the product lifecycle.
  • Support regulatory/notified body requests; directly interact with notified bodies (e.g., TUV, BSI).
  • Identify/evaluate risks and drive resolution; participate in continuous improvement.
  • Follow health, safety, and environmental (HSE) practices; ensure compliance (and supervise subordinates’ HSE compliance if applicable).
Qualifications/Requirements:
  • MS or PhD in Toxicology (or related); required.
  • 6+ years relevant medical device industry.
  • 8–10 years in toxicology/biocompatibility assessments (medical device/pharma/consumer); medical device experience strongly preferred.
  • Regulated environment experience supporting submissions/audits; worldwide registration support preferred.
  • Experience with absorbable biomaterials for implantable devices (degradation/toxicokinetics); required.
  • Knowledge of ISO 10993 biocompatibility/toxicology assessment and relevant standards; required.
  • Familiarity with ISO 13485, ISO 10993, ISO 14971, and design control.
  • Strongly preferred: lab animal care & use; manufacturing process understanding.
Required/Preferred Skills:
  • Team collaboration, conflict resolution, technical leadership/mentorship.
  • Strong written/verbal communication; proactive problem-solving.
  • Travel up to 10%.
Benefits (time off):
  • Vacation (120h/yr)
  • Sick time (40h/yr; CO/Washington adjustments)
  • Holiday pay (13 days/yr)
  • Personal/Family time (up to 40h/yr)
  • Parental leave (480h)
  • Bereavement (240h immediate/40h extended)
  • Caregiver leave (80h)
  • Volunteer leave (32h)
  • Military spouse time-off (80h)
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