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Principal Statistical Programmer Jobs in Raleigh, NC

Caidya

Principal Biostatistician

Morrisville, NC · On-site

Job Title: Principal Biostatistician Job Location: US - Remote Job Overview: Provides all ... Special expertise in more complex statistical analytical methods not well known to all ...

Fortrea

Principal Biostatistician - FSP

Durham, NC · On-site +1

$115K - $130K/yr

As an experienced Principal Biostatistician in our sponsor-dedicated Flexible Solutions business ... and review Statistical Analysis Plans for data presentation, analyses, and provide programming ...

MMS

Principal Biostatistician - Remote

Raleigh, NC · On-site

Can review or develop ADAM specifications; can work with programmers and junior statisticians to resolve comments. * High technical level, Subject Matter Expert in biostatistics; willing to guide ...

UCB

Principal Statistician, Raleigh, NC

Raleigh, NC · On-site

Make your mark for patients We are looking for a Principal Statistician who is collaborative ... Proficient in statistical programming (e.g., SAS or R) and simulation tools * Strong stakeholder ...

UCB

Principal Statistician, Raleigh, NC

Raleigh, NC · On-site

Make your mark for patients We are looking for a Principal Statistician who is collaborative ... Proficient in statistical programming (e.g., SAS or R) and simulation tools * Strong stakeholder ...

IQVIA

Principal R Programmer

Durham, NC

$98.20K - $273.20K/yr

Bachelor's degree in Math, Stats, Computer Science or similar * 5+ years of industrial experience * Must have advanced R programming skills, including tidyverse, ggplot2, Markdown, Quarto, Shiny, etc.

IQVIA

Principal R Programmer

Durham, NC

$98.20K - $273.20K/yr

Bachelor's degree in Math, Stats, Computer Science or similar * 5+ years of industrial experience * Must have advanced R programming skills, including tidyverse, ggplot2, Markdown, Quarto, Shiny, etc.

IQVIA, Inc.

Principal R Programmer

Durham, NC · On-site

$98.20K - $273.20K/yr

Bachelor's degree in Math, Stats, Computer Science or similar * 5+ years of industrial experience * Must have advanced R programming skills, including tidyverse, ggplot2, Markdown, Quarto, Shiny, etc.

Microsoft

Principal Circuit Design Engineer

Raleigh, NC · On-site

$188K - $304.20K/yr

We are looking for a Principal Circuit Design Engineer with a passion for envisioning and creating ... Devise methodologies for statistical analysis and timing/power/EMIR characterization. * Run quality ...

Red Hat

Principal Software Engineer

Raleigh, NC · On-site

$131.20K - $175.90K/yr

... Principal Software Engineer to join their Performance and Scale Organization. The role involves ... statistical analysis and experimental design techniques. • Excellent communication and ...

Redhat

Principal Software Engineer

Raleigh, NC · On-site +1

$151.51K - $249.95K/yr

... Principal Software Engineer to join the Team. This strategic role will require you to demonstrate ... Knowledge of statistical analysis and experimental design techniques. * Excellent communication and ...

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Principal Statistical Programmer information

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How much do principal statistical programmer jobs pay per hour?

As of May 29, 2026, the average hourly pay for principal statistical programmer in Raleigh, NC is $82.20, according to ZipRecruiter salary data. Most workers in this role earn between $70.82 and $94.86 per hour, depending on experience, location, and employer.

What is a Principal Statistical Programmer job?

A Principal Statistical Programmer is a senior-level professional responsible for developing, validating, and maintaining statistical programs used in clinical trials and regulatory submissions. They ensure data accuracy, adherence to industry standards (such as CDISC), and compliance with regulatory requirements. They collaborate with statisticians, data managers, and clinical teams to analyze and report trial results. Additionally, they may mentor junior programmers and contribute to process improvements in statistical programming workflows.

What are the key skills and qualifications needed to thrive in the Principal Statistical Programmer position, and why are they important?

To thrive as a Principal Statistical Programmer, you need advanced expertise in statistical programming (typically with SAS or R), a strong understanding of clinical trial data, and a degree in a relevant field such as statistics, mathematics, or computer science. Familiarity with CDISC standards (SDTM, ADaM), regulatory submission requirements, and project management tools is highly valued, and certifications like SAS Certified Advanced Programmer can be advantageous. Leadership, problem-solving, attention to detail, and excellent communication skills are important for managing complex projects and collaborating across multidisciplinary teams. These skills collectively ensure accuracy, regulatory compliance, and successful delivery of statistical programming support within clinical research environments.

What are the typical daily responsibilities of a Principal Statistical Programmer in a clinical research setting?

As a Principal Statistical Programmer, your daily responsibilities often include developing, validating, and maintaining complex statistical programs to support clinical trial data analysis and regulatory submissions. You may lead programming teams, mentor junior staff, and act as a technical expert on study projects, collaborating closely with statisticians, data managers, and clinical teams. The role frequently involves reviewing statistical analysis plans (SAPs), generating data listings and summary tables, and ensuring adherence to industry standards such as CDISC. Effective communication and time management are key, as you’ll often work on multiple projects simultaneously, balancing deliverables and troubleshooting technical challenges. This position offers diverse, impactful work where your expertise significantly contributes to the integrity and success of clinical research programs.
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Principal Statistical Programmer jobs near you
Infographic showing various Principal Statistical Programmer job openings in Raleigh, NC as of May 2026, with employment types broken down into 100% Full Time. Highlights an 44% In-person, and 56% Remote job distribution, with an average salary of $170,973 per year, or $82.2 per hour.
Principal Biostatistician

Principal Biostatistician

Caidya

Morrisville, NC • On-site

Full-time

Posted 6 days ago

Job description

Job Description:
Job Title: Principal Biostatistician
Job Location: US - Remote
Job Overview:
Provides all biostatistical services to meet the requirements of all Caidya clients, including full-service, Global Clinical Analytics (GCA), and other type studies.
Job Duties and Responsibilities:
A Principal Biostatistician is expected to be a very successful Senior Biostatistician who establishes excellence in one or more areas providing some unique leadership to Caidya. Examples of areas of excellence include but are not limited to:
  • Proven written and oral communications with regulatory agencies.
  • Special expertise in more complex statistical analytical methods not well known to all biostatisticians.
  • Established expertise in a medical therapeutic area.
  • Established a long-term high-level relationship with a Caidya sponsor.
  • Overall high-quality work and a strong reputation for statistical knowledge.
  • Exhibited leadership and organizational skills to plan, supervise, implement, and monitor the statistical processes for multiple clinical trials.
  • Demonstrated ability to adapt and adjust to changing priorities and deal with uncertainty and risks.
  • May be given some supervisory responsibilities for junior staff or department areas.

Supervisory Responsibilities:
  • No supervisory responsibilities.

Job Requirements:
Education
  • PhD or Master's in statistics or related area, or equivalent degree globally

Experience
  • PhD + 7-10 years (or MS + 10 years) experience in pharmaceutical, CRO, or related environment.

Skills/Competencies
  • Interpersonal and communication skills: Excellent written and oral communication skills including technical writing of all statistical results.
  • Ability to develop professional presentations for presenting statistical issues and solutions to clients internally.
  • Ability to effectively learn and handle new or unfamiliar statistical methods.
  • Ability to find needed written resources and interact with other Biostat staff with the needed familiarity.
  • Willingness to share expertise with junior staff members.
    Capabilities
  • Excellent broad ranging understanding of statistical methods and issues. Demonstrates leadership in several areas of statistics.
  • Has a developed expertise in 1-2 therapeutic areas.
  • Ensures statistical quality: Reviews and monitors quality of statistical tasks and project deliverables provided by statistical project team.
  • Deep working knowledge of clinical drug development process: In-depth understanding of phases of clinical trials and relevant statistical considerations that apply to Phase I-IV studies and non-inferiority concepts.
  • Has strong knowledge of GCP and ICH guidelines and other regulatory guidelines related to statistics.
  • Develops capability for interacting with regulatory agencies on behalf of sponsor matters. Such capability would include ability to write statistical reports and/or present oral arguments to such agencies.
  • Ability to serve as a Project Manager for GCA studies. Coordinate keeping tasks and project activities in line with agreed timelines and budget.
  • Excellent training and presentation skills: Has the ability to clearly communicate statistical concepts and successfully train and develop staff through coaching and presentations.
  • Strong understanding of departmental and company procedures which relate to tasks that are performed routinely: Strong understanding of all departmental SOPs and good understanding of all required company SOPs.
  • Familiarity with Caidya Functional Areas that Biostatistics interacts with on a regular basis (Proposals, Finance, Clinical Operations, Data Management, Medical Writing), and updates appropriate personnel regarding project scope changes which may impact their areas.
  • Support the Business Development process through RFP process, bid defenses, attendance at scientific meetings, etc.

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About Caidya

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

1,001 - 5,000 Employees

Headquarters location

Morrisville, NC, US

Year founded

2021

Social media

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