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Principal Scientist Jobs in Raleigh, NC (NOW HIRING)

LexisNexis

Principal Data Scientist I

Raleigh, NC

$118K - $219K/yr

Principal Data Scientist I Are you looking to develop your Data Scientist career? Would you like to be part of a team that innovates using technology? Responsibilities * Acting as a leader for ...

慨正橡扯

Principal Data Scientist I

Raleigh, NC · On-site

$118.30 - $219.80/hr

Principal Data Scientist I Are you looking to develop your Data Scientist career? Would you like to be part of a team that innovates using technology? Responsibilities * Acting as a leader for ...

Redhat

Principal Data Scientist

Raleigh, NC · On-site +1

$147K - $243K/yr

S. Build data science solutions for business challenges including customer propensity, product forecasting, and recommender systems. Use machine learning, data mining, and statistical methods to ...

IQVIA

Principal, Patient-Centered Research

Durham, NC · On-site

IQVIA provides scientific services spanning clinical trials, real world evidence, and consulting in ... Role & Responsibilities As a Principal within the PCS team, you will primarily focus within the ...

Guidehouse

Bioinformatics Scientist

Durham, NC · On-site

Scientist Travel Required: None Clearance Required: Ability to Obtain Public Trust What You Will Do ... principal component, meta-analysis, and related statistical analyses. * Interpret genomic and ...

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Showing results 21-40

All JobsPrincipal Scientist JobsPrincipal Scientist Jobs in Raleigh, NC

Principal Scientist information

See Raleigh, NC salary details

$66.6K

$140K

$185.2K

How much do principal scientist jobs pay per year?

As of Aug 13, 2026, the average yearly pay for principal scientist in Raleigh, NC is $139,988.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,200.00 and $164,300.00 per year, depending on experience, location, and employer.

What is a principal scientist?

A principal scientist takes the lead in research and development on a project. Staff researchers turn to the principal scientist for guidance and direction. As a principal scientist, your job duties include developing the research strategies to be used on the project, directing the research of staff scientists assigned to the project, and monitoring the progress of the study. The principal scientist may also be required to report progress to management and the funding organization.

How much does a principal scientist earn?

A principal scientist typically earns between $100,000 and $160,000 annually, depending on experience, industry, and location. They often hold advanced degrees and have extensive expertise in their field, which can influence salary levels.

Do you need a PhD to be a principal scientist?

A PhD is often required for a principal scientist role, especially in research-intensive fields, as it demonstrates advanced expertise and research skills. However, some organizations may consider candidates with extensive industry experience and a master's degree combined with a strong track record of accomplishments. Additional skills such as leadership, project management, and technical proficiency are also important for this position.

What is the difference between Principal Scientist vs Senior Scientist?

AspectPrincipal ScientistSenior Scientist
Required CredentialsAdvanced degrees (PhD or equivalent), extensive research experienceMaster's or PhD, significant research background
Work EnvironmentLeads research projects, strategic planning, cross-functional collaborationConducts experiments, data analysis, supports project goals
Employer & Industry UsageResearch institutions, biotech, pharma, tech companiesResearch labs, R&D departments in similar industries

The main difference between a Principal Scientist and a Senior Scientist lies in their level of responsibility and scope. Principal Scientists typically lead research initiatives, set strategic directions, and have more experience, while Senior Scientists focus on executing research tasks and supporting project objectives. Both roles require advanced degrees and research expertise, but Principal Scientists hold a higher leadership and strategic role within organizations.

What are the key skills and qualifications needed to thrive as a principal scientist, and why are they important?

To thrive as a Principal Scientist, you need advanced expertise in your scientific discipline, a doctoral degree (PhD or equivalent), and a solid track record of research accomplishments. Familiarity with specialized laboratory equipment, data analysis software, and compliance with regulatory standards is typically required. Strong leadership, project management, and communication skills are essential for mentoring teams and collaborating across departments. These competencies enable Principal Scientists to drive innovation, ensure scientific rigor, and deliver impactful research outcomes.

How does a principal scientist typically collaborate with cross-functional teams in a research organization?

Principal Scientists often serve as key liaisons between research, development, and business units. They lead project teams, facilitate knowledge sharing, and ensure scientific strategies align with organizational goals. Collaboration may involve guiding junior scientists, working with regulatory affairs, and coordinating with manufacturing or quality assurance departments to translate research findings into practical applications. Effective communication and leadership skills are essential, as Principal Scientists must synthesize diverse perspectives to drive projects forward.
More about Principal Scientist jobs

What are the most commonly searched types of Principal Scientist jobs in Raleigh, NC?

The most popular types of Principal Scientist jobs in Raleigh, NC are:

What are popular job titles related to Principal Scientist jobs in Raleigh, NC?

For Principal Scientist jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Principal Scientist jobs in Raleigh, NC look for?

The top searched job categories for Principal Scientist jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Principal Scientist jobs?

Cities near Raleigh, NC with the most Principal Scientist job openings:

Principal Scientist jobs near you
Infographic showing various Principal Scientist job openings in Raleigh, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $139,988 per year, or $67.3 per hour.

Principal Data Scientist I

LexisNexis

Raleigh, NC

$118K - $219K/yr

Full-time

Re-posted 25 days ago

LexisNexis rating

7.6

Company rating: 7.6 out of 10

Based on 17 frontline employees who took The Breakroom Quiz

190th of 491 rated business services

Job description

hackajob is collaborating with LexisNexis to connect them with exceptional professionals for this role.

Principal Data Scientist I 

Are you looking to develop your Data Scientist career? 

Would you like to be part of a team that innovates using technology? 

Responsibilities 

  • Acting as a leader for analytic project and result sharing 

  • Leading code reviews, acting as a final approver of models before reaching customers 

  • Evaluating and creating new frameworks and defining methodologies and governance 

  • Managing and leading small-to-medium sized teams, directly or indirectly 

  • Setting a high-bar for model development 

Requirements 

  • Have excellent communication skills and the ability to convey information clearly to senior stakeholders 

  • Be a natural problem-solver and able to take a lead in collaborating to resolve issues 

  • Have experience in mentoring or training others, and acting as a subject matter expert to guide colleagues 

  • Have some management experience, including leading a team indirectly or directly 

  • Have significant experience in a Data Scientist role 

  • Have experience in leading complex projects and customer relationships {Empty}

U.S. National Base Pay Range: $118,300 - $219,800. Geographic differentials may apply in some locations to better reflect local market rates.

This job is eligible for an annual incentive bonus.

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