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Preformulation Jobs (NOW HIRING)

The University Of Iowa

Formulation Scientist I

Iowa City, IA · On-site

  • Medical

  • Dental

  • Life

  • Retirement

  • PTO

The Formulation Scientist I will report to the Director of Preformulation and Formulation Development and provide support by conducting experiments, investigations, or evaluations. The incumbent will ...

Jj

Scientist, Discovery Pharmaceutics

San Diego, CA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Minimum 1 year of hands-on industry laboratory experience in formulation, preformulation, analytical testing, physicochemical characterization, or a related pharmaceutical sciences area. * Hands-on ...

KBI Biopharma, Inc.

Group Leader / Scientist II

Boulder, CO · On-site

$101 - $138.60/hr

  • Medical

  • Dental

  • Vision

  • Retirement

... preformulation studies, formulation studies, identity testing, and various ad‑hoc stand‑alone tests. The Group Leader/ScientistIIAFS will supervise the daily aspects within the project as well as ...

KBI Biopharma, Inc.

Group Leader / Scientist II

Boulder, CO · On-site

$101K - $138K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

... preformulation studies, formulation studies, identity testing, and various ad-hoc stand alone tests. The Group Leader/Scientist II AFS will supervise the daily aspects within the project as well as ...

KBI Biopharma, Inc.

Group Leader / Scientist II

Boulder, CO · On-site

$101K - $138K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

... preformulation studies, formulation studies, identity testing, and various ad-hoc stand alone tests. The Group Leader/Scientist II AFS will supervise the daily aspects within the project as well as ...

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Preformulation information

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How much do preformulation jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for preformulation in the United States is $37.30, according to ZipRecruiter salary data. Most workers in this role earn between $30.29 and $42.07 per hour, depending on experience, location, and employer.

What is a preformulation?

A Preformulation job involves studying the physical, chemical, and biological properties of drug compounds to guide formulation development. Scientists in this role assess solubility, stability, and compatibility with excipients to ensure the drug's efficacy and manufacturability. Their work helps optimize formulation strategies, reducing risks in later development stages. Preformulation specialists collaborate with analytical, formulation, and regulatory teams to support drug development from early research to clinical trials.

What are the typical responsibilities of a preformulation scientist in a pharmaceutical company?

Preformulation scientists are responsible for investigating and characterizing the physical and chemical properties of drug candidates to inform formulation strategies. They conduct experiments to assess solubility, stability, compatibility, and other key parameters, often collaborating closely with formulation development, analytical, and process engineering teams. Daily tasks may include designing experiments, analyzing data, preparing technical reports, and presenting findings in multidisciplinary meetings. This role is critical for de-risking the formulation process, ensuring optimal drug performance, and facilitating smooth project progression from preclinical through to clinical development.

What are the key skills and qualifications needed to thrive in the preformulation position, and why are they important?

To succeed in a Preformulation role, you need a solid foundation in pharmaceutical sciences, physical chemistry, and analytical techniques, typically supported by a relevant degree (such as pharmacy, chemistry, or pharmaceutical sciences). Experience with laboratory instrumentation like HPLC, DSC, and particle size analyzers, as well as familiarity with regulatory guidelines (e.g., ICH, FDA), is essential. Strong problem-solving, communication, and organizational skills set outstanding candidates apart, as they frequently collaborate across R&D, formulation, and analytical teams. These competencies are vital because preformulation scientists lay the groundwork for successful drug development by characterizing compounds and anticipating formulation challenges early in the process.

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Preformulation jobs near you
Infographic showing various Preformulation job openings in the United States as of August 2026, with employment types broken down into 87% Full Time, 10% Part Time, and 3% Contract. Highlights an 93% Physical, and 7% Hybrid job distribution, with an average salary of $77,584 per year, or $37.3 per hour.

Scientist-II Developability & Preformulation

Sarepta Therapeutics

Columbus, OH • On-site

Full-time

Re-posted 25 days ago

Job description

Why Sarepta? Why Now?

The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.

We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.

What Sarepta Offers

At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:

  • Physical and Emotional Wellness

  • Financial Wellness

  • Support for Caregivers

For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us

The Importance of the Role

The Early Research and Process Development (ERPD) group is seeking a Scientist II with experience in biologics preformulation and developability assessment, with a focus on proteins, antibodies, and antibody-oligonucleotide conjugates (AOCs). This individual will support the assessment of developability for lead molecules through comprehensive evaluations, including biophysical characterization, forced degradation, and short-term, long-term, and in-use stability studies.
The successful candidate will leverage high-throughput formulation tools and workflows to characterize product stability across a broad range of conditions, including process buffers, excipients, concentrations, hold times, and temperatures. In collaboration with Analytical Development, the candidate will help define quality attributes and implement stability-indicating assays appropriate for early-stage programs. The Scientist II will also consider route-of-administration factors, such as subcutaneous delivery, during early formulation assessments (e.g., stability and viscosity at high concentrations, potential enabling approaches).
This role requires strong cross-functional engagement, working closely with Upstream and Downstream Process Development, High-Throughput Automation, and CMC Drug Substance/Drug Product teams to foster a collaborative environment that enables the advancement of robust and scalable manufacturing processes. The Scientist II will contribute formulation recommendations to research, pilot-scale, and commercial-scale manufacturing groups and generate scientifically rigorous data packages to inform preclinical and early clinical development and enable downstream CMC strategy for Sarepta's genetic therapy engine.
Sarepta provides a creative culture that invites you to be the best that you can be and is committed to making a difference in patient's lives. Join us at the Genetic Therapy Center of Excellence here in Easton, Ohio.

The Opportunity to Make a Difference

    • Plan and execute formulation experiments to assess andoptimizethe stability of key intermediates and final products throughout the manufacturing process.

    • Establish developability profiles for candidate molecules, incorporating considerations for route-of-administration.

    • Identifyformulation-relevant critical quality attributes for key intermediates and drug productcandidates andguide the development of stability-indicating assays tomonitorthem.

    • Contribute scientific recommendationsregardingformulation technologies and instrumentation.

    • Support cross-functional teams by providing recommendations on product handling and storage considerations.

    • Prepare and review methods, protocols, and technical reports for regulatory submissions or technology transfer.

    • Train and support Research Associates in experimental execution, troubleshooting, and data interpretation.

More about You

  • Degree in Biochemistry, Biochemical Engineering, Bioengineering, or Chemical Engineering

  • Ph.D. with3-5yearsor M.S. with6-8yearsof biologics formulation experience,

  • Experience withbiologicsformulation(e.g.,mAbs) isrequired. Experience withAOCs or antibody-drug conjugates (ADCs)formulationis a plus.

  • Hands-on experience with protein formulation technologies(e.g., Unchained Labs Big Tuna/Big Kahuna/Junior, Sartorius AMBR Crossflow,Pendotech5TFF, Repligen KR2i, etc.).

  • Experience with stability and analytical assaystomonitorproduct quality, including SEC,RP, CE-SDS,cIEF,DLS, DSF, MALS,and mass spectrometry.

  • Experience with high-concentration formulation challenges (e.g., viscosity mitigation strategies, excipient screening, protein-protein interaction understanding)

  • Experience applying Design of Experiments (DoE) principles to formulation development is a plus.

  • Demonstrated ability to work effectively in cross-functional teams and communicate scientific findings to internal stakeholders.

  • Proficiencyin statistical or data analysis tools (e.g., JMP, GraphPad,SigmaPlot) is a plus.

  • Prior experience in therapeutic protein discovery or biochemistry research.

  • Excellent written and verbal communication skills.

What Now?

We're always looking for solution-oriented, critical thinkers.

So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.

#LI-OnsiteThis position requires work on site at one of Sarepta's facilities in the United States.The targeted salary range for this position is $106,400 - $133,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

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