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How much do preclinical research jobs pay per year?

As of Aug 8, 2026, the average yearly pay for preclinical research in the United States is $56,057.00, according to ZipRecruiter salary data. Most workers in this role earn between $46,500.00 and $47,000.00 per year, depending on experience, location, and employer.

What is preclinical research?

A Preclinical Research job involves studying the safety, efficacy, and biological effects of new drugs, medical devices, or treatments before they are tested in humans. Researchers conduct laboratory experiments and animal studies to gather critical data on toxicity, pharmacokinetics, and mechanism of action. This phase ensures that only the most promising candidates proceed to clinical trials, minimizing risks for human participants. Preclinical researchers work in pharmaceutical companies, biotech firms, or academic institutions, collaborating with regulatory agencies to meet industry standards. Their findings play a key role in shaping drug development and approval processes.

What are the key skills and qualifications needed to thrive in preclinical research?

To thrive in Preclinical Research, you need a solid grounding in biology, pharmacology, and laboratory techniques, often backed by a degree in life sciences or a related field. Experience with laboratory information management systems (LIMS), statistical software, and regulatory compliance (such as GLP certification) is highly valued. Attention to detail, problem-solving skills, and clear communication help professionals excel in collaborative and fast-paced research environments. These competencies are vital to ensure the accuracy, reliability, and integrity of data supporting the development of new therapies.

What are the typical daily responsibilities in preclinical research?

In a Preclinical Research role, your day-to-day responsibilities may include designing and conducting laboratory experiments, collecting and analyzing data, and documenting results in line with regulatory standards. You will likely collaborate closely with scientists, regulatory teams, and sometimes external partners to support the development and safety assessment of new drugs or therapies. Tasks also often involve maintaining laboratory equipment, preparing reports, and presenting findings to project teams. This hands-on environment offers a mix of routine procedures and problem-solving challenges, contributing to meaningful scientific progress.

More about Preclinical Research jobs
What cities are hiring for Preclinical Research jobs? Cities with the most Preclinical Research job openings:
What are the most commonly searched types of Preclinical Research jobs? The most popular types of Preclinical Research jobs are:
What states have the most Preclinical Research jobs? States with the most job openings for Preclinical Research jobs include:
What job categories do people searching Preclinical Research jobs look for? The top searched job categories for Preclinical Research jobs are:
Preclinical Research jobs near you
Infographic showing various Preclinical Research job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 11% Part Time, and 2% Contract. Highlights an 87% Physical, 3% Hybrid, and 10% Remote job distribution, with an average salary of $56,057 per year, or $27 per hour.

Principal Scientist, Preclinical Surgeon

Johnson and Johnson

Cincinnati, OH • On-site

Full-time

Re-posted 28 days ago

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Multi-Family Pre-Clinical Development - Medtech
Job Category:
People Leader
All Job Posting Locations:
Cincinnati, Ohio, United States of America
Job Description:
We are searching for the best talent for a Principal Scientist, Nonclinical Surgery located in Cincinnati, OH.
Purpose: Functioning as a primary surgeon, with a primary focus on cardiovascular procedures, to provide surgical expertise and technical leadership during research, development, and evaluation of surgical devices using animate, inanimate, and cadaveric models. Performing surgical research & testing which support development of products or procedures in standard and minimally invasive surgery (open, laparoscopic, and robotic).
Under general direction and in accordance with all applicable federal, state and local laws/regulations and Corporate Johnson & Johnson, procedures and guidelines, this position will:
  • Conducting and / or directing surgical investigations for product development and preclinical evidence generation.
  • Use scientific and surgical expertise to evaluate functionality, efficacy, and safety of medical devices during acquisition, licensure, discovery, development, and product change evaluations.
  • Provide biomedical expertise by making unbiased recommendations to ETHICON teams regarding new technologies and interaction of device concepts on living tissue.
  • Provide technical direction and execution within Preclinical Research for surgical investigation and development of medical devices.
  • Collaborating with Preclinical Research team to apply clinically relevant models for product evaluation, while meeting preclinical study design, execution, and timeline requirements.
  • Support the Preclinical Research team with the development of animal models.
  • Responsible for communicating business related issues or opportunities to next management level
  • For those who supervise or manage a staff, responsible for ensuring that subordinates follow all Company guidelines related to Health, Safety and Environmental practices and that all resources needed to do so are available and in good condition, if applicable
  • Responsible for ensuring personal and Company compliance with all Federal, State, local and Company regulations, policies, and procedures
  • Know & follow ETHICON policies & procedures related to work activities performed in area of responsibility.
  • Utilize interpersonal skills and collaboration to enhance team processes and drive surgical efficiency/quality within Preclinical Research, ETHICON, and J&J.
  • Function as key Preclinical Research team member by energetically supporting the goals of the department, ETHICON, and J&J by actively participating in and collaborating with the external scientific community.
  • Performs other duties assigned as needed

Education:
  • A minimum of a Doctorate degree is highly preferred (DVM/VMD from an (AVMA) American Veterinary Medical Association accredited program; MD is also acceptable with significant preclinical experience)
  • Surgical residency training and board certification (DACVS) is preferred.
  • Certification as a Surgical Research Specialist (SRS) through the Academy of Surgical Research may also be considered based on experience level.
  • Demonstrated knowledge of surgical principles and theory is required, with specific training in cardiovascular procedures also required.
  • Demonstrated knowledge and experience in performing fluoroscopic angiography in large animals is required
  • Experience in executing preclinical and/or clinical studies, including GLP, with external contract research organizations is preferred.
  • Ability to work collaboratively with the preclinical research team is required.
  • Familiarity with Medical Device Product Development is preferred.
  • Knowledge of preclinical regulatory requirements for FDA and notified bodies outside the US is preferred.

Required Skills & Experience:
  • Extensive knowledge of cardiovascular surgery as well as interventional procedures.
  • Deep knowledge of animal and human anatomy and physiology, as well as biological systems.
  • Demonstrated analytical problem-solving and decision-making skills.
  • Demonstrated surgical expertise during research, development, & evaluation by utilizing animate, inanimate and cadaveric models.
  • Ability to work as a technical leader, team member, and role model for preclinical staff.
  • Excellent communication skills - written/oral/listening.
  • Working with minimal supervision.
  • Ability to clearly document and communicate plans and results.
  • Possess the motivation and work ethic to successfully complete studies/surgical procedures on time and with high quality.
  • Able to manage multiple tasks and responsibilities.
  • Serve as a preclinical subject matter expert on technical/surgical evaluation concerning device performance.
  • Able to bring new scientific principles / innovative technical solutions to projects / studies.
  • Robust surgical technique & mastery of open and laparoscopic procedures spanning multiple animal models. Robotic surgical experience is desired, but not required.
  • Knowledge of regulations regarding medical device development and the utilization of live animals in preclinical research.

Other:
  • This position is based in Cincinnati, OH, and requires up to 25% travel.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

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