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What are the key skills and qualifications needed to thrive in a postdoctoral position in peptide synthesis?

To thrive in a Postdoctoral Position in Peptide Synthesis, you need a PhD in chemistry, biochemistry, or a related field with a solid background in peptide synthesis and purification techniques. Experience with analytical tools such as HPLC, mass spectrometry, and peptide synthesizers, as well as familiarity with relevant software, is typically required. Strong problem-solving abilities, attention to detail, and effective collaboration and communication skills help you excel in multidisciplinary research environments. These skills ensure the successful design, synthesis, and analysis of peptides, contributing to impactful research outcomes.

What are some common challenges faced in a postdoctoral position in peptide synthesis, and how can they be addressed?

Postdoctoral researchers in peptide synthesis often encounter challenges such as optimizing synthetic routes for complex peptides, managing the purification of difficult sequences, and troubleshooting low yields or unexpected side reactions. These hurdles can be addressed by staying current with the latest literature, using advanced purification techniques like HPLC, and collaborating closely with other chemists or biochemists in the lab. Open communication with mentors and team members also helps in brainstorming solutions and sharing best practices, fostering a collaborative environment that is essential for overcoming technical obstacles.

What is a postdoctoral position in peptide synthesis?

A Postdoctoral Position in Peptide Synthesis is a research-focused role for individuals who have recently completed their Ph.D. in chemistry, biochemistry, or a related field. The primary responsibility is to design, synthesize, and characterize peptides for various scientific studies, often in drug discovery or biomedical research. Postdocs in this area may also be involved in developing new synthetic methodologies, analyzing experimental data, and publishing their findings. These roles typically provide training and experience necessary for an academic or industry career in chemical and biological sciences.

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Postdoctoral Fellow - Synthetic Chemist

Indiana University Academic Positions

Bloomington, IN • Hybrid

$45K - $61K/yr

Full-time

Re-posted 13 hours ago

Job description

Position Details
Title Postdoctoral Fellow - Synthetic Chemist Appointment Status Non-Tenure Track Department IU Bloomington Chemistry Location Bloomington Position Summary
The Department of Chemistry in the College of Arts + Sciences at Indiana University consists of a well-rounded research community with cutting-edge expertise in a wide variety of modern disciplines including analytical chemistry, organic chemistry, inorganic chemistry, physical chemistry, materials chemistry, and biochemistry.
The Zaleski Lab in the Department of Chemistry at Indiana University is accepting applications for a postdoctoral research position. The position involves the design and synthesis of hybrid molecular and nanomaterial catalysts (see here for recent work: Accts. Chem. Res. 2019, 52, 1957; Chem. Sci. 2025, 16, 255. The desired start date is July 1, 2026, although this is flexible in-order-to accommodate the needs of outstanding candidates.

The successful applicant will use a deep understanding of synthetic inorganic and organic ligand chemistry, as well as molecule preparation and purification. Nanomaterial design to develop systems for catalysis is a plus but not required. Motivated applicants with a Ph.D. in any area of synthetic chemistry will be considered. A candidate with a strong background in solution-phase synthetic preparations and characterizations, as well as familiarity manipulating air- and moisture-sensitive chemicals, is ideally suited for the project. We seek to employ someone with demonstrable experience in chemical purification and characterization of starting materials and reaction products by standard techniques (NMR, IR, Mass spectrometry, X-ray diffraction, TEM, and DFT calculations also desirable).

The Zaleski Lab is a dynamic multidisciplinary laboratory environment. The successful applicant will play an integral role within our growing team and will emerge with a skill set that is equally relevant to academia and industry. Trainees receive regular guidance and feedback to ensure progress is made toward their career goals, whatever those may be. Trainees are also afforded the scheduling flexibility needed to maintain an appropriate work life balance and a safe laboratory environment.
Responsibilities:

1. Manage own academic research and administrative activities. This involves small scale project management and coordinating multiple aspects of work to meet deadlines.
2. Adapt existing, and develop new, scientific techniques and experimental protocols to achieve research objectives.
3. Use specialist scientific equipment in a laboratory environment.
4. Assist in setting up a new research laboratory at IU (e.g. setting up Schlenk lines, ordering equipment etc.)
5. Contribute ideas for new research projects.
6. Undertake comprehensive and systematic literature reviews and write up the results for publication in peer-reviewed journals.
7. Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters.
8. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.
9. Represent the research group at external meetings/seminars, either with other members of the group or alone.
10. Carry out collaborative projects with colleagues in partner institutions, and research groups.
Basic Qualifications
Required Qualifications:

Ph.D. in Chemistry
Preferred Qualifications:

Experience with organometallic synthesis and relevant analytical techniques (NMR, SXRD, mass- spectrometry etc.) is essential. The preferred candidate will have a deep understanding of organic and/or inorganic synthesis.
Department Contact for Questions
Questions regarding the position or application process can be directed to: Prof. Jeff Zaleski, Department of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN 47405, zaleski@indiana.edu.
Additional Qualifications Salary and Rank 50,000 Special Instructions
The initial appointment for this position will be for 12 months. Additional 12-month extension will be available based on performance. A competitive salary along with a benefits package will be offered.
Interested candidates should submit a cover letter, CV, maximum 5-page research proposal, and contact information for three references to http://indiana.peopleadmin.com/postings/33329. Applications will be reviewed upon receipt.
"Indiana University is an equal employment and affirmative action employer and a provider of ADA services and prohibits discrimination in hiring. See Indiana University Notice of Non-Discrimination here which includes contact information.

For Best Consideration Date 06/10/2026 Expected Start Date 07/01/2026 Posting Number IU-101571-2026

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