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Postdoc Rna Biology Jobs (NOW HIRING)

Alphanumeric

Principal Scientist

Cambridge, MA · On-site

$78 - $83.50/hr

... Biology, Immunology , or related field with 3+ years of postdoctoral and/or industry experience (or MS with 8+ years). * Strong knowledge of molecular biology techniques (cloning, RNA production ...

wistar

Post-Doctoral Fellow - Sarma Lab

Institute, WI

$47.10K - $63.90K/yr

... RNA biology are encouraged to apply. Experience in performing and analyzing data from genomic ... postdoctoral research projects, and career goals. Names and contact information for at least 3 ...

The University of Chicago

Staff Scientist

Chicago, IL · On-site

Projects integrate tumor immunology, RNA biology, radiation biology, and translational studies ... and postdoctoral fellows. * Contributes to data presentation, figure preparation, manuscript ...

Duke University

Research Associate, Senior

Durham, NC · On-site

... Biology with a minimum of 5 years postdoctoral experience * Demonstrate advanced expertise in wet lab experimental systems, tissue cell culture, molecular biology, cell biology, and RNA biology.

Mount Sinai Hospital

Postdoctoral Fellow-MSH

Manhattan, NY · On-site

$53.90K - $73.20K/yr

The successful Postdoctoral candidate will possess a cell/molecular skill set with an emphasis on RNA biology appropriate to accomplish the lab's goals. In addition, they will possess the drive ...

Penn State University

Researcher

Hershey, PA · On-site

Candidates must hold a PhD with at least 5-year experience as a postdoc in the field of bone biology or RNA biology. A Strong publication record and significant experimental training in molecular ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO

$49.80K - $67.60K/yr

The postdoctoral fellow will investigate the molecular mechanism, using a suite of tools including ... Develop new technical expertise as needed, including gaining proficiency in RNA biology and related ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49.80K - $67.60K/yr

The postdoctoral fellow will investigate the molecular mechanism, using a suite of tools including ... Develop new technical expertise as needed, including gaining proficiency in RNA biology and related ...

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Postdoc Rna Biology information

What are the key skills and qualifications needed to thrive as a Postdoc in RNA Biology, and why are they important?

To thrive as a Postdoc in RNA Biology, you need a PhD in molecular biology, biochemistry, or a related field, with deep expertise in RNA mechanisms and experimental design. Familiarity with advanced laboratory techniques such as RNA-seq, qRT-PCR, CRISPR/Cas9, and bioinformatics tools is typically required. Strong analytical thinking, problem-solving, and collaborative communication skills help drive innovative research and effective teamwork. These skills are crucial for advancing scientific knowledge, publishing impactful results, and contributing to dynamic research environments.

What are some typical challenges faced by postdocs specializing in RNA biology, and how can they be addressed?

Postdocs in RNA biology often encounter challenges such as mastering rapidly evolving experimental techniques, managing complex datasets, and balancing independent research with collaborative projects. Staying up-to-date with the latest advances in RNA sequencing and analysis requires continuous learning and adaptability. Building strong communication and networking skills can help overcome these challenges, as collaboration with bioinformaticians, principal investigators, and other lab members is crucial for success. Regularly attending seminars and workshops also supports professional growth and keeps postdocs at the forefront of new discoveries.

What does a Postdoc in RNA Biology do?

A Postdoc in RNA Biology conducts advanced research on the structure, function, and regulation of RNA molecules within cells. Their work often involves designing and performing experiments, analyzing data, and publishing results related to topics such as RNA processing, gene expression, or RNA-based therapeutics. They may also collaborate with other scientists, mentor students, and contribute to grant writing. The goal is to expand scientific understanding of RNA biology and its implications for health and disease.
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Principal Scientist

Principal Scientist

Alphanumeric

Cambridge, MA • On-site

$78 - $83.50/hr

Contractor

Posted 14 hours ago

Job description

Alphanumeric is hiring a PRINCIPAL SCIENTIST to work in Cambridge, MA with our client of 20 years committed to improving lives through medical and pharmaceutical advancements.
Pay Range: $78.00 - $83.50/hour (W2)
W2 only. No C2C or third-party candidates will be considered.
Position Overview
We are seeking a highly motivated Principal Scientist to lead the development of scalable, cell-based assay platforms for evaluating and ranking multi-epitope mRNA construct designs in a high-throughput environment.
This role requires deep expertise in flow cytometry and microscopy-based cellular readouts, with the ability to translate complex assay data into clear, actionable design recommendations to advance mRNA vaccine development.
Key Responsibilities
  • Lead development of cell-based assays to evaluate and rank multi-epitope mRNA construct designs (e.g., expression/presentation proxies, antigen-specific T cell activation, breadth/competition effects).
  • Provide technical leadership in flow cytometry, including panel design, controls, acquisition, gating strategies, SOP development, troubleshooting, and data quality control.
  • Partner closely with Molecular Biology and RNA teams to design and iterate mRNA constructs based on assay outcomes.
  • Establish robust, reproducible workflows using cell lines and/or primary immune cells.
  • Enable high-throughput assay execution (96/384-well formats) with standardized controls and scalable analysis templates.
  • Mentor team members and build internal capabilities around new assay platforms.
  • Ensure data integrity, documentation, and compliance with internal standards; support assay transfer across teams and sites.
  • Stay current on advancements in RNA vaccines, immunology, and assay technologies.
  • Contribute to internal reports, publications, and scientific presentations.
  • Foster a collaborative, high-performance scientific environment.

Job Requirements
Basic Qualifications
  • PhD in Molecular Biology, Cell Biology, Immunology, or related field with 3+ years of postdoctoral and/or industry experience (or MS with 8+ years).
  • Strong knowledge of molecular biology techniques (cloning, RNA production, characterization).
  • Deep understanding of RNA biology and mRNA vaccine design principles.
  • Extensive hands-on experience with flow cytometry (design → execution → analysis) and building reproducible assays.
  • Experience working with immune and/or engineered cell lines.
  • Practical experience with microscopy-based assays (confocal or high-content imaging).
Preferred Qualifications
  • Experience with high-throughput cellular assay development (96/384-well formats, assay miniaturization, robustness metrics).
  • Hands-on experience with automation platforms (e.g., Tecan, Hamilton) or strong collaboration with automation teams.
  • Familiarity with multiplex protein assays (e.g., cytokine panels).
  • Expertise in T cell functional assays and translating results into construct design decisions.
  • Knowledge of antigen processing and presentation pathways.
  • Exposure to immunopeptidomics.
  • Experience with data workflows for high-throughput biology (LIMS, metadata standards, reproducible pipelines).
Must-Have Skills
  • Flow cytometry assay development and analysis
  • Cell-based assay design (immune-focused)
  • mRNA/RNA biology and construct optimization
  • Data interpretation and decision-making for design iteration
  • Cross-functional collaboration (biology + RNA + data teams)
What Type of Individuals Excel in This Environment
  • Scientifically curious and driven to solve complex biological problems
  • Thrive in fast-paced, iterative R&D environments
  • Strong ownership mindset with ability to lead from the bench
  • Comfortable translating data into strategy and action
  • Collaborative and able to influence across cross-functional teams
Nice-to-Have (Edge) Qualifications
  • Experience in vaccine development or infectious disease research
  • Background in biotech/pharma R&D environments
  • Familiarity with AI/ML-supported assay analysis or design workflows
  • Prior experience scaling assays from early research to platform level
Additional Information
  • Industry experience in biotech, pharmaceutical, or related life sciences strongly preferred; adjacent research environments (academic labs, translational research institutes) will be considered.

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