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Operations Manager Startup Jobs in Boston, MA (NOW HIRING)

BioLabs

Lab Operations Associate

Watertown, MA · On-site

$46K - $70K/yr

... startup companies in their most formative years, while developing your own laboratory operations skills in a cutting-edge biotechnology facility. RESPONSIBILITIES * Assist and support the management ...

Prelim

Business Operations Lead

Boston, MA · Remote

$240K - $260K/yr

Our technical account management team. Our two TAMs report to you. You'll hold regular 1:1s, track ... About Prelim Prelim is a San Francisco and New York City-based startup that operates with fully ...

WHOOP

Director, Clinical Operations

Boston, MA · On-site

$200 - $250/hr

... Data Management, Study Startup, and Clinical Operations functions. * Demonstrated experience ... overseeing CRO‑managed clinical studies and external vendor partnerships. * Experience leading ...

Amazon

Senior Station Manager

Revere, MA · On-site

Additional responsibilities include managing and leading a team of Operations, Area and Shift ... Operations or related field and MBA preferred - Experience in a startup environment - Ability to ...

Amazon

Senior Station Manager

Norwood, MA · On-site

Additional responsibilities include managing and leading a team of Operations, Area and Shift ... Operations or related field and MBA preferred - Experience in a startup environment - Ability to ...

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Operations Manager Startup information

See Boston, MA salary details

$33.7K

$68.9K

$128.7K

How much do operations manager startup jobs pay per year?

As of Sep 7, 2026, the average yearly pay for operations manager startup in Boston, MA is $68,939.00, according to ZipRecruiter salary data. Most workers in this role earn between $44,500.00 and $84,200.00 per year, depending on experience, location, and employer.

What is an operations manager startup?

An Operations Manager in a startup oversees daily operations, ensuring efficient processes across different departments. They manage logistics, improve workflows, and implement systems to support scaling. This role requires adaptability, problem-solving, and cross-functional collaboration to streamline operations in a fast-paced environment.

What are some common challenges faced by operations managers in a startup environment?

Operations Managers in startups often face rapid changes in priorities, limited resources, and the need to build processes from the ground up. You may find yourself wearing multiple hats, adapting quickly to evolving business requirements, and problem-solving on the fly. Collaboration with founders and cross-functional teams is frequent, requiring strong relationship-building and negotiation skills. Embracing uncertainty and maintaining flexibility are key to thriving in this dynamic and rewarding role.

What are the key skills and qualifications needed to thrive as an operations manager startup?

Success as an Operations Manager in a startup requires strong organizational, analytical, and project management skills, often supported by a degree in business or a related field. Familiarity with productivity tools like Asana, Trello, and Google Workspace, as well as experience with ERP or CRM systems, is highly valuable. Outstanding adaptability, leadership, and communication skills help candidates excel in this fast-moving and often ambiguous environment. These abilities are vital to drive operational efficiency, coordinate across departments, and support rapid company growth.

What are popular job titles related to Operations Manager Startup jobs in Boston, MA?

For Operations Manager Startup jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Operations Manager Startup jobs in Boston, MA look for?

The top searched job categories for Operations Manager Startup jobs in Boston, MA are:

What cities near Boston, MA are hiring for Operations Manager Startup jobs?

Cities near Boston, MA with the most Operations Manager Startup job openings:

Operations Manager Startup jobs near you
Infographic showing various Operations Manager Startup job openings in Boston, MA as of August 2026, with employment types broken down into 83% Full Time, 13% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $68,939 per year, or $33.1 per hour.

Senior Manager, Manufacturing Operations

Alnylam Pharmaceuticals

Norton, MA • On-site

$134K - $182K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 3 days ago

New

Job description

Overview
The Senior Manager, Manufacturing Operations is an integral part of the Norton Internal Manufacturing team. This role will initially be involved in the start-up of Norton's new commercial Drug Substance manufacturing train, including support for equipment commissioning & qualification, oligonucleotide technology transfer, implementation/optimization of enterprise systems, successful execution of Drug Substance PPQ batches all the way through commercial production and launch. The successful candidate will build and manage multiple shifts for commercial GMP manufacturing in the new train.
This position is an on-site end to end business process owner located in Norton, MA reporting to the Associate Director of Manufacturing - Lead End User.
Key Responsibilities
  • Plans, schedules, and manages deliverables for Train 2 operational readiness and PPQ execution
  • Project lead for designing, implementing, and optimizing SAP to support commercial manufacturing, including setting meeting agenda, driving cross-functional collaboration, and developing schedule to ensure the SAP configuration is completed on time to begin production activities
  • End-user subject matter expert for commissioning and qualification testing of new equipment, including protocol review and approval and support for on-the-floor execution
  • Assists with planning and directing an efficient layout of equipment and flow of materials
  • Assist with design and implementation of electronic logbooks, batch records, and workflows within a new Manufacturing Execution System
  • Hire and train multiple shifts to initially support operational readiness activities and then transition those shifts into supporting daily production activities
  • Establishes leading KPIs maximizing manufacturing schedule adherence
  • Provides coaching, feedback, and guidance for direct and indirect reports
  • Provides guidance to direct and indirect reports regarding departmental goals. Ensures accountability for goal execution
  • Champions a safety mindset and approach
  • Maintains staff by participating in recruiting, selecting, and orienting new hires, including development and delivery of training content
  • Identifies personal growth opportunities for reports, and provides guidance on development plans to achieve those opportunities
  • Partners with the Continuous Improvement subject matter experts to implement lean manufacturing principles and tools. Applies these concepts to maximize efficiency and value.
  • Fosters an open culture by providing support and feedback during regular Gemba walks
  • Drives GMP compliance and understands when to intervene and escalate more significant issues for resolution
  • Partners with Quality functions (internal QA/QC,) to ensure timely review of new and executed batch production records, SOPs, deviations, investigations, CAPAs, and may own and drive change controls as needed
  • Participates in regulatory agency audits / inspections and owns associated CAPA
  • Communicates routine production manufacturing status to department head and assists as necessary with process data retrieval, processing, analysis, and presentation at various meeting forums
  • Provides off-shift on-call support for issues that require escalation on a rotating schedule
  • Collaborate with Engineering, Facilities, EHS, Supply Chain, Quality Assurance, Quality Control, Validation, and others to support above responsibilities

Qualifications
  • B.S. in scientific or engineering field preferred
  • Minimum 10+ years of relevant experience hiring and building a manufacturing team and working in GMP Manufacturing/Contract Manufacturing commercial plant in the Pharmaceutical/ biotech industry with 4+ years of supervisory experience
  • In-depth understanding of commercial GMP manufacturing, continuous improvement, and cGMP regulations.
  • Broad knowledge of US and international regulations and standards (FDA, EMA, ICH). Exposure to government inspections (FDA, EMEA, etc.) for new facility approval or routine surveillance required.
  • Proven ability to work independently, leadership aptitude, and good people skills with the desire and ability to work in a fast-paced, start-up environment
  • Strong collaboration and team-building, communication, and organizational skills required
  • Experience working with third party contractors and vendors
  • Hands-on experience with plant commissioning and startup, including troubleshooting and providing solutions to complex technical and logistical issues is required
  • Excellent written and verbal communication skills
  • Requires proficiency in MS Office applications and SAP.
  • Proficiency with process automation, PI Historian, and LIMS preferred
  • Prior experience with MES/eBR strongly preferred

#LI-LJ1
#LI-Onsite
U.S. Pay Range
$134,600.00 - $182,000.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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