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Operational Technology Engineer Jobs (NOW HIRING)

DT Midstream

Senior OT Engineer - Houston, TX

Houston, TX

$99K - $137K/yr

Senior Operational Technology Engineer At DT Midstream, we've got the energy to achieve great things! DT Midstream owns and operates a diverse, integrated portfolio of midstream pipeline, storage and ...

AK Steel

Operations Technology Engineer

Cleveland, OH

$80K - $105K/yr

The Operations Technology Engineer partners closely with operations, maintenance, and leadership to improve equipment performance, develop best practices, and implement continuous and breakthrough ...

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How much do operational technology engineer jobs pay per year?

As of Jun 21, 2026, the average yearly pay for operational technology engineer in the United States is $85,029.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,500.00 and $94,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Operational Technology Engineer position, and why are they important?

To excel as an Operational Technology Engineer, you need a solid understanding of industrial control systems (ICS), network security, and process automation, often backed by a relevant engineering degree. Experience with SCADA systems, PLC programming, and certifications such as ISA/IEC 62443 Cybersecurity are highly valued in this field. Strong problem-solving, communication, and teamwork skills are essential for effectively collaborating with operations and IT teams. These skills ensure safe, reliable, and efficient management of critical infrastructure in industrial environments.

What are the common day-to-day responsibilities of an Operational Technology Engineer?

Operational Technology Engineers typically monitor, troubleshoot, and optimize industrial automation systems such as SCADA, DCS, and PLCs, ensuring continuous and secure operations. They collaborate with operations, IT, and maintenance teams to implement system upgrades, manage cybersecurity risks, and resolve technical issues. Day-to-day tasks may also include conducting system diagnostics, maintaining compliance with safety regulations, and supporting incident response for any operational disruptions. This role often requires both hands-on fieldwork and analytical problem-solving in a dynamic industrial setting.

What does an Operational Technology Engineer do?

An Operational Technology (OT) Engineer is responsible for managing, maintaining, and securing industrial control systems (ICS) and other OT infrastructure used in manufacturing, energy, and critical industries. They work at the intersection of IT and industrial operations, ensuring the seamless integration of hardware, software, and network systems that control physical processes. Their duties often include system configuration, cybersecurity implementation, troubleshooting, and optimizing automation technologies to improve efficiency and safety.

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What cities are hiring for Operational Technology Engineer jobs? Cities with the most Operational Technology Engineer job openings:
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Operational Technology Engineer jobs near you
Infographic showing various Operational Technology Engineer job openings in the United States as of June 2026, with employment types broken down into 99% Full Time, and 1% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $85,029 per year, or $40.9 per hour.
Senior Operational Technology Engineer

Senior Operational Technology Engineer

Cellares

South San Francisco, CA • On-site

$125K - $172K/yr

Full-time

Posted 6 days ago

Job description

Job Summary:
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) focused on mass manufacturing cell therapies. The Senior Operational Technology Engineer will lead and support IT/OT operations in a global cell therapy manufacturing lab environment, ensuring system reliability, scalability, and regulatory compliance across multiple sites.
Responsibilities:
• Manage and deliver OT systems and technology for the company’s industrial and cell manufacturing environments
• Own and maintain a robust OT roadmap, including project objectives, prioritization, and implementation plans
• Ensure OT production environments adhere to security best practices and comply with relevant regulations
• Provide hands-on technical support and troubleshooting for production-related OT/IT issues, ensuring minimal disruption to 24x7 operations
• Implement and monitor OT production systems to guarantee 24x7 uptime and reliability, including network, server, biotech manufacturing lab, and proprietary equipment
• Develop and deliver training programs for new OT staff relating to production environment
• Contribute to creating, maintaining SOPs, Policies, and Process
• Lead and support GMP-related activities, including change control, system validation, qualification (IQ/OQ/PQ), and audit readiness
• Own OT access management processes, including user provisioning, role-based access control, and periodic access reviews to ensure compliance with GxP, data integrity, and cybersecurity requirements
• Ensure compliance with industry regulations, standards, and best practices related to OT and data security
• Provide backup support to Corporate IT as needed to ensure continuity of enterprise IT services
Qualifications:
Required:
• Bachelor's Degree in related field or proper training
• 7+ years of relevant experience
• Proven experience in IT management with a manufacturing or industrial setting, with a strong focus on 24x7 operational support
• Experience with monitoring, server management, and cybersecurity best practices
• Experience with Fortigate firewalls, Hirschmann industrial switches, lab and warehouse equipment
• Experience with various applications such as Nutanix Prism, SharePoint, and JIRA
• Experience working in a biotech regulated environment
• Knowledge of and experience with current Good Manufacturing Practices (cGMP) required
• Ability to independently prioritize work and deliver results effectively in a fast-paced environment.
• Ability to be a strong problem-solving skills and the ability to work under pressure
• Requires availability for on-call support and extended hours during critical system issues to maintain 24x7 operations
• Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
Company:
Cellares is an Integrated Development and Manufacturing Organization dedicated to the automated, large-scale production of cell therapies. Founded in 2019, the company is headquartered in South San Francisco, USA, with a team of 201-500 employees. The company is currently Growth Stage.
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About Cellares

Sourced by ZipRecruiter

Industry

Pharmaceutical and medicine manufacturing

Company size

11 - 50 Employees

Headquarters location

South San Francisco, CA, US

Year founded

2019

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