The primary qualifications for getting a job as a medical assistant with no experience are a high school diploma and a certificate from a medical assistant certification course or an EMT program. Employers strongly prefer applicants who have Basic Life Support certification from the American Heart Association. Previous experience working in an office can help you stand out from other applicants but isn't required to get a job as a medical assistant. You may be asked to work overtime, nights, weekends, or holidays as needed, so the ability to be flexible with your schedule is essential to your success. Fulfilling the duties and responsibilities of an entry-level medical assistant requires communication skills, the ability to work professionally during medical emergencies, and the ability to follow directions.