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Molecular Modeling Jobs (NOW HIRING)

Guidehouse

Molecular Biologist

Bethesda, MD · On-site

$74K - $124K/yr

Support structure prediction, molecular modeling, and data visualization efforts. * Operate and maintain laboratory instrumentation, including FPLC, BLI, and SPR systems. * Maintain laboratory ...

Guidehouse

Molecular Biologist

Bethesda, MD

$74K - $124K/yr

Support structure prediction, molecular modeling, and data visualization efforts. * Operate and maintain laboratory instrumentation, including FPLC, BLI, and SPR systems. * Maintain laboratory ...

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How much do molecular modeling jobs pay per year?

As of Aug 14, 2026, the average yearly pay for molecular modeling in the United States is $80,687.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,000.00 and $98,500.00 per year, depending on experience, location, and employer.

What is a molecular modeling?

A Molecular Modeling job involves using computer simulations and theoretical techniques to study molecular structures, interactions, and properties. Professionals in this field apply computational chemistry, molecular dynamics, and quantum mechanics to predict molecular behavior in drug discovery, materials science, and biochemistry. They work with specialized software and collaborate with experimental scientists to design and optimize compounds for various applications.

What are the typical career advancement opportunities for someone in molecular modeling?

Molecular modeling professionals can pursue a variety of career advancement opportunities, including progressing to lead scientist or principal investigator roles, moving into project management, or specializing in areas like drug design or materials science. With experience, you may also transition into roles in academia, regulatory affairs, or scientific consulting. Continued professional development through advanced degrees, certifications, or technical workshops can further expand your options and responsibilities. Additionally, collaborating on interdisciplinary projects and publishing research can enhance your reputation and open doors to leadership positions in the field.

What are the key skills and qualifications needed to thrive in molecular modeling, and why are they important?

To thrive in Molecular Modeling, you typically need a strong background in chemistry, biochemistry, or a related field, with a solid understanding of molecular structures and computational methods. Experience with molecular modeling software such as Schrödinger, MOE, or Gaussian, as well as familiarity with scripting languages like Python, is highly valuable. Analytical thinking, problem-solving abilities, and effective communication are key soft skills for interpreting complex data and collaborating with interdisciplinary teams. These qualifications are crucial for accurately modeling molecular systems, advancing research projects, and facilitating successful teamwork in scientific environments.

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Molecular Modeling jobs near you
Infographic showing various Molecular Modeling job openings in the United States as of August 2026, with employment types broken down into 87% Full Time, 10% Part Time, and 3% Contract. Highlights an 84% Physical, 5% Hybrid, and 11% Remote job distribution, with an average salary of $80,687 per year, or $38.8 per hour.

Molecular Biologist

Guidehouse

Bethesda, MD • On-site

$74K - $124K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 19 days ago

Guidehouse rating

7.7

Company rating: 7.7 out of 10

Based on 27 frontline employees who took The Breakroom Quiz

42nd of 72 rated business consultants

Job description

Job Family:
Scientist
Travel Required:
None
Clearance Required:
Ability to Obtain Public Trust
What You Will Do:
We are looking for a Molecular Biologist (Virology Core Biological Scientist) to support the Vaccine Research Center (VRC) at NIAID by performing advanced protein engineering, purification, and characterization work in support of virology and immunology research. This is a full-time position located in Bethesda, MD.
  • Design and optimize recombinant protein expression systems for multiple host platforms.
  • Perform protein purification and characterization using biochemical and biophysical assays.
  • Conduct protein-antibody interaction studies and analyze kinetic data.
  • Support structure prediction, molecular modeling, and data visualization efforts.
  • Operate and maintain laboratory instrumentation, including FPLC, BLI, and SPR systems.
  • Maintain laboratory inventory, documentation, and standard operating procedures (SOPs).
  • Analyze experimental data and support reporting through presentations and manuscripts.
  • Collaborate with NIH investigators and multidisciplinary research teams.

What You Will Need:
  • Master's degree
  • A minimum of THREE (3) years of experience in molecular biology, protein engineering, or related laboratory research.
  • Demonstrated expertise in protein production and purification techniques, including aseptic technique, chromatography, and molecular characterization.
  • Demonstrated proficiency in kinetic analysis, including hands-on experience with BLI or SPR.
  • Ability to operate and maintain protein purification and analytical instrumentation.
  • Familiarity with molecular visualization tools such as PyMOL, ChimeraX, or AlphaFold.
  • Strong collaboration, communication, and organizational skills to support multidisciplinary teams.
  • Proficiency with Microsoft Office Suite and scientific software tools.
  • Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have:
  • Ph.D. in Biochemistry, Molecular Biology, Chemical Engineering, or a closely related biomedical field preferred.
  • Background working with recombinant protein-antibody interaction studies and assay development.
  • Exposure to advanced protein engineering strategies and chimeric protein design.
  • Familiarity with high-throughput kinetic platforms and epitope binning techniques.
  • Ability to support data visualization and structural modeling for scientific communication.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse
Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.
All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.
If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse's Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant's dealings with unauthorized third parties.
Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

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