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Senior Molecular Modeling Jobs (NOW HIRING)

Senior Configuration Engineer (Hybrid)

Rahway, NJ · On-site

$124K - $164K/yr

We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences ... Ph.D. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics ...

Senior Configuration Engineer (Hybrid)

Rahway, NJ · On-site

$124K - $164K/yr

We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences ... Ph.D. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics ...

We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences ... Ph.D. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics ...

$118K - $156K/yr

We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences ... Ph.D. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics ...

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Senior Molecular Modeling information

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$25K

$80.3K

$163.5K

How much do senior molecular modeling jobs pay per year?

As of Jul 27, 2026, the average yearly pay for senior molecular modeling in the United States is $80,287.00, according to ZipRecruiter salary data. Most workers in this role earn between $41,500.00 and $103,000.00 per year, depending on experience, location, and employer.

What are some typical challenges faced by Senior Molecular Modeling professionals in cross-functional research teams?

Senior Molecular Modeling professionals often work closely with medicinal chemists, biologists, and data scientists, which can present challenges in translating complex computational findings into actionable insights for diverse teams. Balancing multiple project priorities and adapting modeling techniques to evolving research goals are common hurdles. Strong communication skills and a collaborative mindset are essential to bridge gaps between computational and experimental perspectives, ensuring that modeling results effectively guide experimental design and decision-making.

What does a Senior Molecular Modeler do?

A Senior Molecular Modeler is a specialist who uses computer simulations and theoretical chemistry techniques to study and predict the structure, properties, and behavior of molecules. They often work in pharmaceutical, biotechnology, or materials science settings, helping to design new drugs or materials by modeling interactions at the molecular level. Their responsibilities include running simulations, analyzing data, developing new modeling methods, and collaborating with experimental scientists to interpret results. Senior roles also typically involve project leadership and mentoring of junior colleagues.

What is the difference between Senior Molecular Modeling vs Molecular Dynamics Specialist?

AspectSenior Molecular ModelingMolecular Dynamics Specialist
Required CredentialsBachelor's/Master's in Chemistry, Biochemistry, or related fields; experience with modeling softwareBachelor's/Master's in Chemistry, Physics, or related fields; strong background in simulation techniques
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsResearch labs, pharmaceutical companies, biotech firms
Industry UsageDesigning molecular structures, drug discovery, material scienceRunning molecular dynamics simulations, analyzing simulation data
Common Search/ComparisonOften compared due to overlapping skills in modeling software and research goalsSpecializes in dynamic simulations, but overlaps with modeling tasks

While both roles involve computational chemistry and software tools, Senior Molecular Modeling focuses on creating and analyzing molecular structures, whereas Molecular Dynamics Specialists primarily run and interpret dynamic simulations to understand molecular behavior over time.

What are the key skills and qualifications needed to thrive as a Senior Molecular Modeler, and why are they important?

To thrive as a Senior Molecular Modeler, you need advanced knowledge in computational chemistry, molecular modeling, and structural biology, typically supported by a PhD in a related field. Proficiency with software tools like Schrödinger, MOE, AMBER, and programming languages such as Python or R is essential. Strong problem-solving, communication, and collaborative skills help you effectively interpret results and work within multidisciplinary teams. These skills and qualities are crucial for driving innovative drug discovery and accurately predicting molecular interactions.
What cities are hiring for Senior Molecular Modeling jobs? Cities with the most Senior Molecular Modeling job openings:
What are the most commonly searched types of Molecular Modeling jobs? The most popular types of Molecular Modeling jobs are:
What states have the most Senior Molecular Modeling jobs? States with the most job openings for Senior Molecular Modeling jobs include:
Senior Configuration Engineer (Hybrid)

Senior Configuration Engineer (Hybrid)

Merck & Co.

Rahway, NJ

$124K - $164K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 5 hours ago


Merck rating

8.0

Company rating: 8.0 out of 10

Based on 51 frontline employees who took The Breakroom Quiz

42nd of 86 rated pharmaceutical


Job description

Job DescriptionWe are a global biopharmaceutical leader with a portfolio of prescription medicines, oncology, vaccines and animal health products. We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to inspire our employees as we learn, develop and grow in our careers. -We are proud of our over 125 years of service to humanity and continue to be one of the world's biggest investors in Research & Development.We are seeking a Senior Scientist to join our Digital Insights team within the Development Sciences and Clinical Supply (DSCS) Digital Technologies organization. Digital is the multiplier that will allow DSCS to deliver better experiments faster, efficient filing and launch, more robust supply chains and higher-confidence decisions across the portfolio.The DSCS Digital Technologies organization is responsible for the invention and application of new digital tools/workflows to support scientists across drug substance development, drug product development and analytical development. We aspire to embed digital technologies into the fabric of DSCS culture to drive transformational impact. The tools that we develop are as the teams developing them, and in this Senior Configuration Engineer role, the successful candidate will leverage their expertise in working with ELN configuration and structured data design to enable standardized, high-quality data capture across CMC workflows. The person in this role will work across our company small molecule, biologics, and vaccines portfolio with an initial focus on helping deliver the staged implementation of a unified CMC data model through scalable ELN configuration.The candidate will be tasked with leading the design, configuration, and governance of Admin Defined Templates (ADTs), Worksheets, and experiment templates within the Signals platform to ensure consistent, structured capture of experimental data at the source. This includes, but is not limited to, translating complex scientific workflows into reusable templates with embedded logic, aligning Signals configurations to enterprise data models, and enabling seamless integration with downstream analytics, machine learning, and regulatory systems. This role sits within the Digital Insights team which is working to digitally enable a decision engine for DSCS, by innovating solutions through strong partnership in the domains of Data Science, Data Analysis, Informatics, Multi-Omics, Predictive Science, and Data Engineering.Responsibilities: Lead the design, configuration, and lifecycle governance of Signals configurational elements to standardize data capture across CMC workflowsAlign configuration development to the unified CMC data model and phased implementation roadmapTranslate scientific workflows into scalable templates with embedded logic, validation rules, and ontologiesPartner with scientists, SMEs, and digital product teams to drive adoption and ensure templates meet scientific and operational needsEnsure data quality, harmonization, and reusability, enabling integration with analytics, ML, and regulatory systemsEstablish and enforce standards for template designContribute to continuous improvement of ELN configuration practices and broader DSCS digital transformation initiativesEducation Minimum Requirement: Ph.D. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related fieldM.S. in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related field with at least 2 years of industrial/pharmaceutical or relevant experienceB.S. in in Computer Science, Data Science, Molecular Modeling, Engineering, Chemistry, Physics, Biology, Pharmaceutical Sciences, or a closely-related field with at least 4 years of industrial/pharmaceutical or relevant experienceRequired Experience and Skills: Experience configuring ELN platforms, with strong expertise in structured templatesDemonstrated ability to translate scientific workflows into structured data designs, including controlled vocabularies, formulas, and validation rulesStrong CMC domain knowledge across analytical, process, formulation, and drug substance/product developmentExperience supporting enterprise data model or platform implementations, including source-to-canonical data mappingWorking knowledge of GxP requirements, data integrity principles (ALCOA+), and validated SDLC practicesExcellent communication skills, demonstrated creativity, and effective interpersonal skillsAbility to deliver complex solutions under compressed timelines in a dynamic environmentAbility to work in a team environment with cross-functional interactionsMotivated to learn new skills, willingness to take on new challenges, and scientific curiosityPreferred Experience and Skills: Hands-on experience configuring Revvity Signals ADTs at scale within an enterprise environmentExperience leading or contributing to enterprise data model or data harmonization initiatives in pharma R&D/CMCProficiency with Databricks, SQL, Python, or Spotfire for downstream data enablementFamiliarity with ontologies and data standards (e.g., Allotrope, internal CMC vocabularies)Demonstrated leadership in driving standards adoption and establishing communities of practiceExperience with data pipeline tools such as DatabricksExperience with relational databases and SQLExperience with common process and analytical capabilities commonly utilized in pharmaceutical developmentEvidence of cross-functional collaborationsRequired Skills: Analytical Acumen, Biopharmaceutical Industry, Computer Science, Cross-Functional Collaboration, Data Analytics, Data Format, Data Model Design, Data Modeling, Data Quality, Data Science, Design Changes, Digital Transformation Initiatives, Enterprise Data Modeling, Informatics, Innovation, Intellectual Curiosity, Interpersonal Interactions, New Product Introduction (NPI), Pharmaceutical Sciences, Software ConfigurationsPreferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your Rights EEOC GINA Supplement• We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.Learn more about your rights, including under California, Colorado and other US State Acts The salary range for this role is $117,000.00 - $184,200.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: -We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: -We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully-Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.-Employee Status: RegularRelocation:No relocationVISA Sponsorship:No Travel Requirements: 10%Flexible Work Arrangements:HybridShift:1st - DayValid Driving License:NoHazardous Material(s):n/aJob Posting End Date:08/7/2026 *A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:R404695 Salary: . Date posted: 06/27/2026

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