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Microglia Research Jobs (NOW HIRING)

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC

Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more ... and even microglia. Building on this work, we seek to harness the power of this new tool to ...

Mount Sinai Hospital

Postdoctoral Fellow-MSH

Manhattan, NY · On-site

$53K - $73K/yr

Mindur will perform research at the Cardiovascular Research Center. The project will primarily ... microglia/macrophages and through driving the differentiation of monocytes into monocyte-derived ...

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Microglia Research information

What are some typical challenges faced when conducting microglia research in a laboratory setting?

One common challenge in microglia research is maintaining the viability and purity of microglial cultures, as these cells are highly sensitive and can be easily activated by external stimuli. Researchers often need to troubleshoot protocols frequently and adjust to variability in cell responses. Additionally, distinguishing microglia from other glial cells in mixed cultures or tissue samples can require advanced techniques such as flow cytometry or immunostaining. Collaboration with neuroscientists, immunologists, and bioinformaticians is also essential to interpret complex data and advance projects efficiently.

What is microglia research?

Microglia research is the scientific study of microglia, which are specialized immune cells found in the central nervous system. Researchers in this field investigate how microglia function in both healthy and diseased brains, including their roles in neuroinflammation, brain development, and neurodegenerative diseases like Alzheimer's. The aim is to better understand how microglia contribute to brain health and to identify potential therapeutic targets for neurological conditions.

What are the key skills and qualifications needed to thrive in Microglia Research, and why are they important?

To thrive in Microglia Research, you need a strong background in neuroscience, cellular/molecular biology, and experimental design, typically with a PhD or relevant advanced degree. Familiarity with technical tools such as immunohistochemistry, flow cytometry, imaging techniques (e.g., confocal microscopy), and data analysis software (e.g., ImageJ, GraphPad Prism) is crucial. Strong analytical thinking, attention to detail, and collaborative communication skills are essential soft skills in this role. These competencies ensure rigorous experimental work, insightful data interpretation, and effective teamwork in advancing understanding of microglial function and pathology.
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POSTDOCTORAL ASSOCIATE

POSTDOCTORAL ASSOCIATE

Duke University

Durham, NC

Other

Posted 5 days ago

Duke University rating

6.7

Company rating: 6.7 out of 10

Based on 55 frontline employees who took The Breakroom Quiz

446th of 544 rated colleges and universities

Job description

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.Be You.

Department: Neurosurgery 

Job Description:

Fully funded postdoctoral positions are immediately available in the Department of Neurosurgery at the Duke University School of Medicine. We are seeking candidates interested in leading projects based on advancing the development and application of focused ultrasound for non-invasive neuromodulation, ablation, and brain drug/gene delivery. The successful candidate will be an integral part of the research team, conducting independent experiments investigating focused ultrasound based neuromodulation, presenting at weekly lab meetings and research conferences, and working with collaborators at Duke and beyond. 

Be Bold.

Requirements:

The applicant should have a Ph.D., M.D., or equivalent title in biomedical science or a related field. A highly motivated, independent candidate with a passion for translational neuroscience is preferred. Expertise in neurobiology, electrophysiology, mechanotransduction, ultrasound, or in vivo mouse work is highly desirable but not required. 

Lab Background:

We are a high-energy, highly passionate translational neuroscience lab focused on understanding the role of synaptic plasticity in neurologic disease and how this can be directly modulated for disease modification (Harward et al., Nature 2016; Hedrick et al., Nature 2016; Krishnamurthy et al., Ann Neurol 2019). We are particularly interested in developing focused ultrasound as a new method for non-invasively modulating brain activity. Briefly, Focused Ultrasound has recently emerged as a ground-breaking new non-invasive, image-guided therapy to treat Essential Tremor (ET) and Parkinson's Disease (PD). While it is used clinically to make small lesions in the brain circuitry responsible for both ET and PD, additional work has shown that when applied at lower intensity and frequency, it can be used to transiently and focally (with sub-millimeter precision) to open the blood brain barrier, induce local immune responses, and even activate excitatory neurons, inhibitory interneurons, astrocytes, and even microglia. Building on this work, we seek to harness the power of this new tool to optimize its therapeutic use for a wide variety of conditions including epilepsy, neuropsychiatric disease, movement disorders, chronic pain, and brain tumors. To accomplish these goals, we employ a wide range of experimental approaches including viral infections, mouse genetics, in vitro and in vivo preparations, electrophysiology, calcium imaging, optogenetics, and focused ultrasound. 

How to apply:

If interested, please submit a cover letter describing your prior research experience and interests, your future research and career goals, and an expected starting date. Additionally, please submit a current CV and that name of three references.

 Choose Duke. 

Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions:

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


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Duke is regarded as one of America's leading research universities. Located in Durham, North Carolina, Duke is positioned in the heart of the Research Triangle, which is ranked annually as one of the best places in the country to work and live. Duke has more than 15,000 students who study and conduct research in its 10 undergraduate, graduate, and professional schools. With about 40,000 employees, Duke is the third largest private employer in North Carolina, and it now has international programs in more than 150 countries.

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Colleges, universities, and professional schools and hospitals

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10,000+ Employees

Headquarters location

Durham, NC, US

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